Activated PI3Kδ syndrome (#APDS) is a rare immune disorder with significant unmet needs, including misdiagnosis and delayed diagnosis. In Spain, a multidisciplinary committee evaluated APDS treatment using multicriteria decision analysis (#MCDA). Current treatments are mainly off-label and provide limited disease control, with haematopoietic stem cell transplantation being the only potential curative option but with restricted use. The study highlights APDS's high economic burden and suggests MCDA as a valuable tool for enhancing clinical and decision-making processes.| https://ow.ly/rOes50SgXrI
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Did you know graft-versus-host disease (GVHD) can occur after a blood stem cell transplant? This condition happens when donor cells attack a recipient's organs and/or tissues. While it can be serious, it can also be managed. As a proud member of the GVHD Alliance, we're working together with leading transplant organizations to improve access to resources and support for patients with GVHD like Olivia. Discover more about the alliance's collective efforts and help us spread the word this coming GVHD Day 👉 https://lnkd.in/eDXmJmaQ #GVHDDay #GVHDAlliance #NMDP
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A Path to Recovery: Allogeneic Stem Cell Transplantation Allogeneic stem cell transplantation can be a lifeline for those battling some blood cancers, blood disorders, and immune disorders. *Learn more about this life-saving treatment. Consult your doctor for detailed information and personalized advice. #StemCellTransplant #CancerTreatment #Healthcare #MedicalAdvancements #PatientCare #mgmcancerinstitute
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https://lnkd.in/ekXPQpvj Article title: Acute Panmyelosis with Myelofibrosis: The Serpentine Road to Diagnosis Author(s): Celia Suriu; Andrei Braester; Masad Barhoum Journal: Annals of Bone Marrow Research Journal ISSN: 2692-4684 Abstract: cute Panmyelosis with Myelofibrosis (APMF) is an extremely rare disease. Lack of familiarity with this rare subtype of acute leukemia hinders the diagnosis [1]. It is characterized by an acute, rapidly progressive, fatal clinical course, peripheral blood cytopenias with minimum 20% blast and no detectable splenomegaly. APMF corresponds to less than 1% of the cases of Acute Myeloid Leukemia (AML) [2]. Histologically, APMF is characterized by a heavily fibrotic marrow, an increased number of immature hematopoietic elements (panmyelosis), and dysplastic population of megakaryocytes. The condition should be differentiated from other hematological neoplasms that present with fibrosis such as acute megakaryoblastic leukemia and myelodysplsia (MDS) with myelofibrosis. Dacrocytes are not present. #BoneMarrow #BloodSamples #Hematology #AutoimmuneDiseases #StemCells #Immunology #Transplantation #MinimalInvasiveSurgeryTechniques #TranscriptionFactors #Medication #TropicalTreatments #Metabolism #Mortality #DrugTargeting #DrugSensitivity #Resistance #HabitsAndLifestyle #PrognosticFactors #Pathophysiology #NovelDrugs #CellularTherapy #TranslationalResearch #MesenchymalStemCell #HematopoieticStemCellTransplantation #BoneMarrowTransplantation #BoneMarrowEdema #BoneMarrowCancer #BoneMarrowBarrier
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Early diagnosis by GP/family doctor is crucial to improving patient clinical outcomes. In the interview, Dr. Giovanni Marconi, Hematologist and Researcher at the University of Bologna, explains the critical phases for achieving an early diagnosis of leukemia, where the GP/family doctor plays a fundamental role in detecting the disease and correctly referring the patient to a specialist. #Alan #WLD24 #worldleukemiaday2024 #DrMarconi #Hematology #interview #Doctors #FamilyDoctor #GPs #GP #patients #diagnosis #disease #leukaemia #leukemia
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Product Specialist | Business Development | Sales and Marketing | Biotechnology | Lifescience | Healthcare | Antibodies
🌟Watch our on-demand webinar on the therapeutic potential of Regulatory T cells (Tregs)!🌟 Access it here: https://lnkd.in/gMS5-Wyy Tregs are essential for maintaining immune balance and preventing autoimmune diseases like lupus and graft-versus-host disease. Discover how expanding Tregs can restore this balance and offer a promising therapeutic approach. Learn about the technology that ensures high-fold expansion of suppressive Tregs with a stable FOXP3 phenotype and robust suppressive function. Key takeaways: 🔹 Achieve >800-fold expansion of Tregs after two stimulations 🔹 Activate and expand Tregs in a closed, automated system 🔹 Explore the potential of CAR-engineered Tregs in treating autoimmune diseases, organ transplants, and stem cell transplantation #Immunotherapy #Webinar #Tregs #AutoimmuneDisease #Transplantation #MedicalResearch
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Multiple myeloma (MM) is a plasma cell malignancy in which monoclonal plasma cells proliferate in bone marrow, resulting in an overabundance of monoclonal paraprotein (M protein), destruction of bone, and displacement of other hematopoietic cell lines. First described in 1848, MM is part of a spectrum of diseases ranging from monoclonal gammopathy of unknown significance (MGUS) to plasma cell leukemia. #Laboratory #Pathology #Connections #Blood #Health #Healthcare
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https://lnkd.in/gxXEhq62 Infonet Transplant Basics: Preparing a Safe Home You'll need a place to recover after a bone marrow or stem cell transplant that minimizes your risk of developing an infection until your immune system fully recovers. #BMTinfonet #GVHD #CarTcell #CaringConnections #SurvivorshipSymposium #stemcelltransplantsurvivor
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Type 1 Diabetes Lifestyle Coach | 👪Mentoring 500+ DParents 💙 Founder: Unstoppable Type 1 👨💼Entrepreneur
A remarkable case from China has reignited hope for those living with Type 1 diabetes. A woman underwent a stem cell transplant and began producing insulin again. But while the treatment seems promising, the patient must rely on immunosuppressants, which carry significant risks such as infection and even cancer. It’s a major step forward in research, but experts advise caution. Long-term studies over the next 5 years are essential to understand the full impact of this treatment. #DiabetesResearch #MedicalBreakthrough #Type1Diabetes #StemCellTherapy
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Technical Sales Specialist Middle East at Thermo Fisher Scientific | Customer centric advocate to make the world healthier, cleaner and safer
🌟Watch our on-demand webinar on the therapeutic potential of Regulatory T cells (Tregs)!🌟 Access it here: https://lnkd.in/gMS5-Wyy Tregs are essential for maintaining immune balance and preventing autoimmune diseases like lupus and graft-versus-host disease. Discover how expanding Tregs can restore this balance and offer a promising therapeutic approach. Learn about the technology that ensures high-fold expansion of suppressive Tregs with a stable FOXP3 phenotype and robust suppressive function. Key takeaways: 🔹 Achieve >800-fold expansion of Tregs after two stimulations 🔹 Activate and expand Tregs in a closed, automated system 🔹 Explore the potential of CAR-engineered Tregs in treating autoimmune diseases, organ transplants, and stem cell transplantation #Immunotherapy #Webinar #Tregs #AutoimmuneDisease #Transplantation #MedicalResearch
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Circulating Angiogenic and Senescent T Lymphocytes in Ageing and Frailty. Byrne, T. et al.. https://lnkd.in/ecAdwkHM @SETUIreland #Senescent #Lymphocytes #Ageing #Frailty
Circulating Angiogenic and Senescent T Lymphocytes in Ageing and Frailty - The Journal of Frailty & Aging
link.springer.com
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