Read this case study to understand how Aragen’s expert team of scientists helped its client obtain more than 80 mg of a mammalian secretory protein, whose expression in its soluble precursor form is considered challenging in recombinant protein expression systems. Aragen’s team redesigned the workflow to create a cost-effective, scalable process to achieve successful expression of the untagged protein in E. coli expression system and facilitate its subsequent in vivo maturation. The team optimized expression parameters to enhance yield of the recombinant protein’s mature form. We further refined and optimized the initial trial protocol provided by the client to meet standard quality and quantity requirements for the final product. Subsequently, our team redesigned the purification protocol to attain standard specifications in a scalable format with reduced turnaround time. This case study highlights Aragen's expertise, instrumental in reshaping the client's strategy and achieving a critical milestone. To read the whole case study click here https://lnkd.in/gHcgKmMa or write to us at info@arage.com #invivo #invitro #drugdiscovery #drugdevelopment #casestudy #lifesciences #endtoendsolutions #protein
Well done!!!
MPHARM
6moIntresting 💯