BIAL Foundation’s Post

Beautiful introduction! Looking forward to learn from rest of the videos in this series.

Missed our webinar? Don’t worry! You can still catch all the breakthroughs in revolutionizing your #neurodegenerative drug discovery and development with our precise, multiplexed #biomarker assays. Watch our on-demand webinar and see how Inoviv is revolutionizing the field with advanced #proteomics solutions. Don’t miss out on this chance to fast-track your research goals. Watch here - https://lnkd.in/eQDGX3MV #Neurodegeneration #Neuroscience #DrugDiscovery

It's the first #ReadoftheWeek of 2024! In this article, we spoke with Erica Schwartz Koenig, Vice President of Global Clinical Development at Cerevel Therapeutics, to learn more about emraclidine and the challenges of #neuroscience research. https://bit.ly/48vkPtU

Today, we’re excited to introduce ELPIS—our groundbreaking study bringing new hope to patients with CDKL5 Deficiency Disorder (CDD), a rare genetic condition. #ELPIS is the first study of its kind dedicated to this disorder. Our mission is to validate innovative biomarkers for CDD, focusing on: 📌 Plasma Microtubule Proteins 📌 Neurological Plasma Biomarkers With over $600,000 in initial funding and an additional $584,000 recently awarded by the Loulou Foundation, ELPIS is expanding its research across seven countries. Contact us to learn more and explore partnership opportunities in this pioneering research. Read the news 👉 https://shorturl.at/LvkLa #CDKL5 #Biomarkers #Neuroscience #GlobalResearch #UlyssesNeuroscience #EEG #PatientCentricity #Research

in vitro Calcium Imaging can help you understand your compounds' mechanisms of action at the neuronal network level. ➡ Streamlined Lead Selection: Optimize your lead compounds with a functional assay that rapidly demonstrates their impact on neuronal networks. ➡ Long-Term Monitoring: Measure neuronal activity over extended periods using e.g. organotypic slice cultures. ➡ Cell-Type Specific Insights: Utilize genetically encoded dyes for precise, cell-type specific monitoring. ➡ Versatile Integration: Combine with other techniques like patch-clamp for single-cell calcium transient analysis or viral shRNA expression for targeted gene silencing in organotypic brain slices. Ready to advance your research? We're here to support you! 📧 contact@ephyx-neuroscience.com to explore how our expertise can enhance your research journey. 🚀 We look forward to connecting and discussing your project! #Electrophysiology #DrugDiscovery #CNSResearch #DrugDevelopment #PreclinicalResearch #ResearchAndDevelopment #Neurophysiology #CentralNervousSystem #Neuroscience #CRO #Pharma #ContractResearch

Cellular Senescence Shapes Aging and Brain Function Check out our blog post https://wix.to/lXONWVh #Neuroscience #BrainHealth #Aging #Research #Neurodegeneration #Science

Sometimes over-simplifying complex things can lead to missed opportunities. Did you know there are possibly 7 subtypes of dopaminergic neurons based on neurotransmitters they co-release? And that in Parkinson's disease, we lose the DA neurons in the substantia nigra, but also let the cholinergic-gabaergic neurons in the striatum run wild? Could the striatum be a new focus for drug delivery and new treatment targets? I certainly think so! We have enough NGS and proteomic data to design more effective drugs for Parkinson's and also think about new neural transplantation/engineering approaches. #Neuroscience #Bioinformatics

I'm thrilled to share that my latest research paper title, “BBPT attenuated 6-OHDA-induced toxicity by modulating oxidative stress, apoptotic, and inflammatory proteins in primary neurons and rat models of Parkinson’s disease” has been published in NeuroToxicology journal to investigates the role of BBPT (New A2A R antagonist) in 6-OHDA induced model of PD and the neuroprotective effects of A2A receptor antagonists invitro and invivo model of Parkinson's disease. A special thank you to my advisor, Prof. Pratibha Mehta Luthra, my senior, colleagues and everyone who supported me throughout this journey. This research would not have been possible without the guidance and expertise were invaluable throughout this research journey and I am grateful to be part of such an innovative and supportive environment. For those interested, you can access the full paper here: https://lnkd.in/gsUqHkMi I'm looking forward to engaging with fellow researchers and professionals in the field of neuroscience, neuropharmacology and Parkinson's disease. Feel free to reach out if you’d like to discuss potential collaborations or share insights on this topic!!!!!!!!! #Parkinsonsdisease #Neuroscience #Neuropharmacology #A2A #ROS #Oxidativestress #Apoptosis

#WorldParkinsonsDay Today, we recognize World Parkinson's Day, a time to raise awareness about Parkinson's disease and support those affected by it. 🧠 Let's stand together in solidarity, spreading understanding, and advancing research towards a cure.💪 Our humanized B6-hSNCA mouse model serves as a valuable tool for PD research, offering insights into disease mechanisms and potential therapies. 🐭 Leveraging our TurboKnockout technology, we can customize models with specific mutations, supporting diverse experimental needs in pharmacology and PD-related fields. Learn more about this model: https://lnkd.in/gZt7ZNbC #ParkinsonsAwareness #neuroscience #knockout #bioengineering #phd #phdlife #scienceandtechnology #research #researchanddevelopment #biotech #biotechnology #sciencecommunication #preclinical #preclinicalresearch 

🧪 At OWL Metabolomics, we're a leading #Metabolomics company; we're your end-to-end partner in a wide spectrum of therapeutic and investigation areas. Our expertise in #Metabolomics services transcends to diverse fields – #Neuroscience, #Oncology, #MetabolicDiseases, and more –, unraveling the metabolic landscapes in health and disease. 🔗 Explore our expertise in metabolomics through our scientific publications to see the impact of our services in a broad spectrum of research and therapeutic areas. Discover how you can boost your research at: https://lnkd.in/dXzDjZvR. Partner with us to uncover the #MetabolicLandscapes that matter in your work. 🌐 #Metabolomics #OWLMetabolomics