CelVivo’s Post

Gain precise insights into the immune system’s response to diseases with autoantibody profiling. Discover the advantages of immunoprofiling in a compelling podcast or get highlights from a quick 3-min read: Podcast: https://lnkd.in/evRnR2ZD Article: https://lnkd.in/eZDscMKA

Our off-the-shelf and custom animal models continuously advance cutting-edge biomedical research. Custom models generated by our proprietary CRISPR-based Extreme Genome Editing (EGE) platform have been featured in numerous high-impact journals. Check out this publication using our B-NDG hIL15 mice: https://lnkd.in/dWmw66sX #preclinicalresesarch #mousemodel #immunooncology #immunotherapy #therapeutics #antitumortherapy #cancertherapy #cancerresearch #humanizedmodel

What cool science can you do with Millicell® inserts? In this is the 3D merged figure, our researchers show the co-localization of cilia and Ace2 using PromoCell® primary human lung cells on a 0.4 µm Millicell® insert. #cellbiology

What cool science can you do with Millicell® inserts? In this is the 3D merged figure, our researchers show the co-localization of cilia and Ace2 using PromoCell® primary human lung cells on a 0.4 µm Millicell® insert. #cellbiology

Exciting strides in xenotransplantation have unlocked promising avenues for organ transplantation, overcoming critical challenges. This breakthrough not only revolutionizes healthcare but also presents a significant commercial opportunity. Leveraging pig organs for transplantation can address the organ shortage crisis, creating a lucrative market for biotech and healthcare industries. George Church eGenesis, Inc. OrganOx TransMedics, Inc. CRISPR Therapeutics #Xenotransplantation #BiotechInnovation #OrganTransplants #HealthcareAdvancements #CommercialOpportunity

Great review of the safety of non replicative herpes vectors.

Every translational biologist that I have met has always wanted to put their "brick in the wall" of science that builds something amazing whether that be our understanding of ourselves or diseases that we face. To do this we need the best tools and finding biomarkers from our own immune system can provide essential information that can be leveraged to understand disease progression, effects of treatment and the mechanisms used in disease. Sengenics identifies these biomarkers. Could it help you? #proteomics #biomarkers #immunology #cancer #neuroscience

We are proud that Trends in Molecular Medicine, a leading peer-reviewed publication, have published an article based on HSV vectors. It is co-authored by Samuel D. Rabkin, of Harvard Medical School and Massachusetts General Hospital and a leading expert in the field, and our Founder and CSO Alberto Epstein.   The article, titled Safety of Non-Replicative and Oncolytic Replication-Selective HSV Vectors, explores how herpes simplex virus type 1 (HSV-1), a DNA virus and human pathogen, has been used to construct promising therapeutic vectors.     Such vectors have been approved by multiple regulatory agencies and demonstrate a relatively benign safety profile. Most recent non-replicative vectors elicit only limited immune responses. The review highlights vectors translated to the clinic, and host-virus immune-interactions allowing for safety and efficacy of HSVs.   Click below for the full article. #genetherapy #biotech #drugdevelopment

🔍 Case Study: Reimagined Gene Therapy Delivery Device Discover how Kaleidoscope Innovation transformed a gene therapy delivery device, revolutionizing the way ophthalmologists administer treatments. This multi-phase project began with clinical trials, focusing on enhancing the efficiency of the trial rollout. We developed a comprehensive training curriculum, materials, and anatomical simulators to streamline the process. 🔧 Device Redesign: Our team then embarked on redesigning the drug delivery device for commercial readiness. The goal was to improve usability, clinical consistency, and delivery precision. Through innovative design and development, we engineered a device that dramatically decreased procedure time and enhanced injection consistency. 🎯 Results: The reengineered drug delivery device has transformed the treatment landscape for ophthalmologists. With improved usability and precision, it has revolutionized the way gene therapy is administered, ensuring better patient outcomes. 📈 Ready to Learn More? Download the full case study to dive deeper into our process and results: #MedicalDevices #GeneTherapy #Innovation #CaseStudy #Healthcare #Ophthalmology #ClinicalTrials #DownloadNow https://lnkd.in/gSAp9mRr