Computomics’ Post

🤗 Welcome back to “Make Sense of Science”, where we break down complex research into easier-to-understand insights. Today, we take a look at #CoCoPred, an innovative tool developed by our colleague Friederike Lüdtke 🥳 CoCoPred uses machine learning to predict optimal codon usage for organisms, boosting protein production by analyzing the context of surrounding amino acids. This innovation could benefit medicine, agriculture, and industrial applications by enabling more efficient protein synthesis in organisms like bacteria and yeast 🧬🧫 Here's how 👉 https://lnkd.in/d8ZtRnDp #MakeSenseOfScience #ProteinSynthesis #MachineLearning #CodonOptimization #Biotechnology

🔍 𝐔𝐧𝐥𝐨𝐜𝐤𝐢𝐧𝐠 𝐍𝐚𝐭𝐮𝐫𝐞'𝐬 𝐄𝐧𝐳𝐲𝐦𝐞 𝐓𝐫𝐞𝐚𝐬𝐮𝐫𝐞 𝐂𝐡𝐞𝐬𝐭: 𝐄𝐱𝐩𝐥𝐨𝐫𝐢𝐧𝐠 𝐜-𝐋𝐄𝐜𝐭𝐚'𝐬 𝐄𝐧𝐳𝐲𝐦𝐞 𝐄𝐧𝐠𝐢𝐧𝐞𝐞𝐫𝐢𝐧𝐠 𝐓𝐞𝐜𝐡𝐧𝐨𝐥𝐨𝐠𝐲 🌱 Discovering the right enzymes is at the heart of c-LEcta's innovative enzyme engineering technology. With an abundance of microorganisms in nature, even the smallest environmental samples can yield valuable candidates for developing enzyme products. Dr Rico Czaja, Head of Enzyme Discovery and Bioprospecting, emphasizes the diverse sources of these microorganisms, from soil to extreme locations like the Arctic and hot springs. c-LEcta's treasure trove boasts around 10,000 strains from various biotopes, showcasing a rich portfolio of enzymes. Environmental samples, including those from unexpected sources like baby diapers and contaminated industrial soil, are analyzed to extract the genetic information of microorganisms. This genetic treasure, known as the metagenome, is then translated into enzymes through special production bacteria, creating libraries that are stored at -150°C for future screening. Read full article here: https://lnkd.in/eY-My_Ym This post is part of a series on our 20𝐭𝐡 𝐛𝐢𝐫𝐭𝐡𝐝𝐚𝐲 this year, in which we look behind the scenes.  #EnzymeEngineering #Biotechnology #Innovation

SDBN Feed: Microbial Cell Factories May Help Get to the Root of Understudied Plant Molecules https://lnkd.in/gzpVTXc6 A new tool could make it easier to study scarce and mysterious plant molecules. Researchers co-led by the University of California San Diego have developed so-called microbial cell factories—using E. coli and yeast—to produce a [...]

If you have been wanting to learn how to dissect your own meristem, this is your chance! Join Our Plant Meristem Dissection Webinar on June 14th! 🌱 🔬 What We'll Explore: ✅ Choosing the Right Plants: Tips on selecting the best plants for meristem dissection. ✅ Using a Microscope: Practical advice on setting up and mastering a dissecting microscope. ✅ Dissection Techniques: Step-by-step guidance on effective meristem dissection. Meristem tissue culture is not just about growing plants—it's a strategic approach to removing viral pathogens that can compromise plant health. This technique allows you to start with virus-free material, ensuring healthier plant cultures. Whether you're just starting out or looking to refine your techniques, this webinar is designed to provide valuable insights and practical skills. How to Join: 👉 For the Webinar: https://lnkd.in/gFJ-84j2 👉 Interested in More? Click here to attend an upcoming Master Class for a comprehensive dive into tissue culture: https://lnkd.in/eS8W6GYD Mark your calendars and get ready to dive into the world of plant tissue culture with us! #PlantScience #TissueCulture #PlantBiology #Microscopy #PlantTissueCulture #tissuecultureplants #tissueculturelab #tissuecultureclones #tissuecultured #planttissueculturelab #horticulture #micropropagation #washingtondc ##propagation #biotechnology #cultivation #plantpropagation #cultivator #invitropropagation #cloning #plantsofinstagram #invitroplants #meristem

As we explored in the previous post, microorganisms 🦠 develop defenses to survive in the environment. As they form colonies, they create complex matrices that ensure, among other things, their survival and habitat. These polymeric networks, built by microorganisms through their metabolism, are pivotal for sustainability. At Nat4Bio 🍋, we harness microbiology to study various microbial polymers, which we then use to develop our coatings. This allows us to create a technology that does not produce negative effluents, does not use harsh chemicals that harm the environment, and does not require large amounts of natural resources💧. Leveraging our deep expertise in microbiology and materials science, Nat4Bio coatings are produced naturally and with a focus on circular economy, without genetic modificated organisms, and with no cells in the final products. #Coatings #MicrobialPolymers #Microbiology

The success rate of micropropagation is affected by various factors, and one of them is the employment of good lab practices. So, here are Esco's 5 tips to prevent plant tissue culture contamination. May you harvest the fruits of your efforts! Learn more here: https://lnkd.in/gddK9mQj #PlantScience #TissueCulture #Biotechnology #LabSafety #Research #LaminarFlowCabinet #LabEquipment #PlantBiotechnology #Micropropagation #QualityControl

This is what happens when you introduce a jellyfish protein into a yeast cell. It glows in Cultiply’s brand colors: violet and yellow! This blend of science and branding comes to life thanks to our molecular biology specialist, Cristina Corral-Ramos. In this video, we’re giving you a look behind the science into the recombinant protein technology that makes this possible. Here’s why it matters: Recombinant proteins turn microorganisms, like yeast, into powerful protein producers with applications spanning from life-saving medicines to sustainable solutions in food, energy, and environmental sectors. #Biotech #Biotechnology #Sciart #Scicomm #Recombinantprotein #Bioprocess

Understanding the balance between cytokinins and auxins can dramatically affect the outcomes of your tissue culture projects: 𝐂𝐲𝐭𝐨𝐤𝐢𝐧𝐢𝐧𝐬 ✅ BAP (Benzylaminopurine): A synthetic cytokinin that boosts shoot proliferation. ✅ Kinetin: Derived from DNA degradation, it's used to encourage cell division. High cytokinin-to-auxin ratios generally favor 𝙨𝙝𝙤𝙤𝙩 𝙛𝙤𝙧𝙢𝙖𝙩𝙞𝙤𝙣. 𝐀𝐮𝐱𝐢𝐧𝐬 ✅ IAA (Indole-3-acetic acid): A natural auxin that aids in root initiation. ✅ IBA (Indole-3-butyric acid): Synthetic, helps root initiation in challenging species. ✅ NAA (Naphthaleneacetic acid): A synthetic option commonly used to stimulate root formation. High auxin-to-cytokinin ratios generally promote 𝙧𝙤𝙤𝙩 𝙙𝙚𝙫𝙚𝙡𝙤𝙥𝙢𝙚𝙣𝙩. 💡 Explore More: Dive deep into the strategic use of these regulators to optimize your tissue culture results. Whether you're aiming for robust root systems or vigorous shoot proliferation, the right balance can make all the difference. 👉 Want to learn how to apply these concepts effectively in your lab? Register for an upcoming tissue culture master class: https://lnkd.in/eS8W6GYD #GrowthRegulators #tissueculture #tissuecultureplants #planttissueculture #tissueculturelab #tissuecultureclones #tissuecultured #planttissueculturelab #horticulture #micropropagation #plantmicropropagation #nursery #agriculture #plantlife #urbanjungle #invitro #propagation #biotechnology #clone #agtech #cultivation #plantpropagation #indoorplantsdecor #loveplants #plantcommunity #invitropropagation #cloning #inhousegenetics #micropropagacion #invitroplants

We are excited to share more about how Sticta Biologicals is leading this transformative project "Unraveling the Metabolic Landscape of Porcine cells: A Genome-scale Modeling Approach" in collaboration with Meatable, Merken Biotech, and the CMM - Center for Mathematical Modeling. In this project we’re developing a genome-scale metabolic model of porcine cells that will:   🔬 Predict the most efficient ways to nourish porcine cells for maximum growth and yield. 🔬 Boost cell line expansion while minimizing variability in production. 🔬 Innovate media solutions, leveraging critical metabolites for enhanced cellular growth. We integrate cutting-edge tools such as mathematical modeling, synthetic biology, bioinformatic and bioprocess engineering to develop a groundbreaking genome-scale metabolic model of porcine cells.   At Sticta, we are at the forefront of biotech solutions, delivering essential growth factors and recombinant proteins, to the global cultivated meat industry. Our mission is to accelerate the commercialization of sustainable, affordable cultivated meat by helping companies achieve price parity with conventional meat.   We're excited about the progress made so far and remain committed to pushing the boundaries of what’s possible in sustainable food technology. A big thank you to our partners and the The Good Food Institute for supporting this vital research.   Stay tuned for more updates as we embark on this exciting journey toward a more sustainable food future! 🌱   Together, we're pushing the boundaries of sustainable food technology! 🌍 #StictaBiologicals #CultivatedMeat #SustainableFood #Biotechnology #GoodFoodInnovation #AlternativeProteins #FutureOfFood #CellularAgriculture #PrecisionFermentation #SynBio Eduardo Agosin Andres Ariztia Elliot Swartz

#analyticalchemistry news Exploring new frontiers in #chemistry, recent research published in *Talanta* introduces an innovative MALDI matrix that promises to enhance the analysis of metabolites. This study by a team of dedicated scientists, featuring the compound 1,4-Dioxo-1,2,3,4-tetrahydrophthalazine-6-carboxylic acid, offers a revolutionary approach to studying the biochemical impacts of imidacloprid exposure. You can access the full article [here](https://lnkd.in/dYc3yUWQ,. Matrix-Assisted Laser Desorption/Ionisation, MALDI, is a powerful technique widely used in mass spectrometry to analyse biomolecules. This study demonstrates how the new MALDI matrix significantly improves the detection of metabolites, showcasing enhanced sensitivity and resolution compared to traditional methods. Such advancements are crucial in the field of analytical #chemistry, where precise and accurate detection of chemical compounds is often challenging due to complex biological matrices. Imidacloprid, a neonicotinoid insecticide, is commonly used in agriculture. However, its impact on the environment and human health has sparked concerns across the globe. By employing this novel MALDI matrix, researchers can now achieve a deeper understanding of the metabolic alterations caused by imidacloprid, thereby enabling more robust risk assessments and better-informed decisions regarding agricultural practices. What does this mean for you? With enhanced analytical tools, scientists and policymakers can offer improved strategies for #sustainable agriculture and environmental stewardship. These findings could lead to more effective monitoring of pesticide residues, ultimately contributing to safer food production and a healthier planet. Let's embrace a future where scientific advancements guide us towards more responsible and informed choices. #Chemistry #AnalyticalChemistry #Sustainability #ResearchInnovation #EnvironmentalHealth, If you want to know more about #analyticalchemistry news, follow me: https://lnkd.in/d29pbjb9