Cornea : The Journal of Cornea and External Diseases’ Post

ICYMI: Cornea Update: Overview of Mycotic Keratitis: Abstract: Keratomycosis is a serious corneal infection associated with high ocular morbidity that can lead to severe vision loss. It is estimated to affect more than 1 million patients annually, most commonly occurring in tropical climates, and represents a growing threat to patients worldwide. Despite aggressive medical management, fungal infections have a higher rate of perforation requiring surgical intervention compared with other infectious etiologies. Early diagnosis and appropriate treatment are keys to preserving vision and saving patients' eyes. http://dlvr.it/T731GY #Cornea #Ophthalmology #Ophthotwitter

As predictable brain link implants rejected by brain tissue, expelling/disconnecting them, in addition to risk of infection/forced implantation. NEUROTRON vascular catheters and/or capturing post input/ex-vivo output signal: https://lnkd.in/dNKN6x-Y

📘 IPIP ARTICLE SPOTLIGHT 📘 Hair removal with a clipper and microbial colonisation prior to knee arthroplasty: a randomised controlled trial. Despite the widely reported success of knee arthroplasty, studies show that 1.6–3 % of patients undergo revision within the first postoperative year predominantly due to infection. Preoperative skin preparation may potentially decrease the bacterial load and consequently, the risk of periprosthetic joint infections. The effects of hair removal on prosthetic joint infection are inconsistent. The primary aim for this study was to investigate if hair removal with a clipper influenced skin colonisation and bacterial composition. Read FULL ARTICLE for free 👉 https://ow.ly/OhfN50SwIVJ

The pathophysiology of Meleney's gangrene involves a complex mechanism of tissue necrosis driven by the interaction of bacteria and the host's immune response. The infection typically begins in the skin and subcutaneous tissues, where bacteria enter through a break in the skin, such as a surgical incision, wound, or ulcer. Once inside, the bacteria release toxins and enzymes that break down the surrounding tissues. The body’s immune response, which attempts to fight the infection, inadvertently contributes to tissue destruction by causing inflammation and swelling, further impairing blood flow to the affected area. As the infection progresses, inadequate blood supply leads to tissue ischemia, exacerbating the necrosis. The affected area typically becomes red, swollen, and increasingly painful, with the skin eventually turning dark or black as the tissue dies. Unlike other types of gangrene, where tissue necrosis can occur rapidly, Meleney's gangrene develops more gradually, allowing for a window of opportunity for diagnosis and intervention if recognized early. Learn more about it here: https://bit.ly/4eICdP1 #meleneysgangrene #gangreneawareness #woundcare #tissuenecrosis #infectioncontrol #woundhealing #chronicwounds #skinhealth #medicaleducation #necrotizingfasciitis #surgicalcare #healthcareprofessionals #severeinfections #tissueischemia #woundtreatment #inflammation #earlydiagnosis #patientcare #infectiousdiseases #woundprevention #skininfections #woundmanagement #immuneresponse #healthcaretips #surgicalwound

Editorial: The global #monkeypox outbreak raises urgent concerns about overlooked complications, including ophthalmological issues. Studies highlight a 2x higher risk of uveitis in monkeypox patients. Clinicians must stay vigilant for intraocular inflammation. https://lnkd.in/eYNbYFtp #Ophthalmology

The Hidden Danger: Hospital-Acquired Infections (HAIs) At NOBiotics, we understand that healthcare should be safe, yet Hospital-Acquired Infections (HAIs) pose a significant threat to patient safety. The CDC reports that about 1 in 31 hospital patients has an HAI on any given day, leading to 99,000 deaths annually in the U.S. alone. Why Are HAIs Dangerous? HAIs can cause prolonged hospital stays, increase healthcare costs, and sadly, higher mortality rates. Common types include surgical site infections, urinary tract infections, and ventilator-associated pneumonia. How Can We Prevent HAIs? Hygiene Practices: Handwashing and proper sanitization are essential. Antimicrobial Stewardship: Responsible antibiotic use helps combat resistance. Innovative Solutions: At NOBiotics, we’re dedicated to developing effective antibacterial solutions. Take Action! You can help prevent HAIs by staying informed, advocating for safety, and supporting research efforts. Together, we can create a safer healthcare environment. Join us at NOBiotics in the fight against HAIs! Follow NOBiotics! #healthcare #infections #scientists #biomedical #PhD #biotechnology (Image Citation: Global Alliance for Infections in Surgery)

FRESH OFF THE PRESS: Crescentic Autograft—Graft Salvage Technique for Undersized Donor Lenticules in Superficial Anterior Lamellar Keratoplasty: Purpose: To describe the use of crescentic autograft as a graft salvage technique for inadvertently undersized donor lenticules in superficial anterior lamellar keratoplasty (SALK). Methods: A prospective interventional study included 5 eyes of 4 patients who underwent SALK and had an inadvertently undersized donor lenticule. The described technique involves the preparation of a crescent-shaped graft from the host lenticule itself that is matched to fit into the remaining bare recipient stromal bed. Results: At 6-week follow-up, the crescentic autograft was uniformly epithelized along with the donor tissue. There were no incidences of graft dehiscence, rejection, or infection. Conclusions: Crescentic autograft from the host lenticule offers a simple, easy-to perform, and unique technique to manage cases of undersized donor lenticules in SALK with no additional risks. http://dlvr.it/TH4bk7 #Cornea #Ophthalmology #Research

Here we go, we’re back with new FAQs, this week's on #suspectedsepsis in patients 🌟 ❔ Question: Can MeMed BV® be used to diagnose sepsis? ✔  Answer: Although MeMed BV is not indicated for the diagnosis of Sepsis, current guidelines emphasize the importance of promptly assessing the likelihood and cause of infection in suspected sepsis patients. MeMed BV demonstrates high accuracy in distinguishing between bacterial and viral infections in this specific patient population and may help in rapid assessment of infection etiology with a result within 15 minutes of blood draw. References: 1. Angel et al. Annals of Emergency Medicine 2023, 2. Chambliss et al. Clinical Chemistry 2023, 3. Bracken et al. Current pediatric reports 2023 *Suspected sepsis patient defined as ≥2 age-adjusted SIRS criteria (a surrogate marker for possible sepsis) https://lnkd.in/dw_T7DrY

In a search of the available literature the authors identified 37 patients with PJIs receiving adjunctive Phage Therapy. A random-effects proportional meta-analysis suggested infection remission in 78% of patients (95% CI: 39%, 95%) (I2 = 55%, p = 0.08) and 83% with a minimum 12-month follow-up (95% CI: 53%, 95%) (I2 = 26%, p = 0.26). Conclusions: Our study provides a preliminary estimate of PT’s efficacy in PJIs and informs future comparative studies. Stephanie Lesage https://lnkd.in/eMDRwHZP

New content from the Surgical Infections Journal: 'ERAS and Gastrointestinal Site Infections: Insights from a Comprehensive Systematic Review and Meta-Analysis' Read it here 👉 https://lnkd.in/gmGrdZSm