Curiosis’ Post

September is Healthy Aging Month—a time to celebrate innovations that support the journey toward a healthier future for aging adults. This month, we’re excited to spotlight Biopico Systems INC, which is revolutionizing vitro biomedical research. Biopico's OrganRX™ accurately mimics human physiology, enabling more precise drug discovery, disease pathology studies, and regenerative medicine research. This first-in-class innovation provides valuable data on how drugs interact with multiple organs, which is crucial for developing effective treatments for complex diseases like Alzheimer’s. Explore how Biopico Systems is advancing the future of biomedical research and promoting healthy aging with their transformative technology: bit.ly/3M4tJ #NIAFunded #HealthyAgingMonth

Watch the key message from Professor Laura Niedernhofer's talk, which delves into the promising potential of Fisetin in reducing cellular senescence. In vitro studies highlighted Fisetin's efficacy in selectively eliminating senescent cells, and in vivo studies demonstrated its benefits in extending lifespan and reducing age-related damage in mice. Despite challenges in clinical trials and the need for personalized approaches, these compounds show promise in combating aging and inflammation. Watch the snippets below for more insights. University of Minnesota Andrea B. Maier NUS Yong Loo Lin School of Medicine #UHL24 #AgingResearch #CellularSenescence #Fisetin #HealthyLongevity #Longevity #HealthSpan #Neuroprotection

For the latest issue of the Swiss National Science Foundation SNSF Horizon magazine, I had an interesting conversation with Alexander Ehret and Costanza Giampietro from Empa about a new endothelial cell layer model they developed. Available in EN, FR and DE. #sciencejournalism #vascularbiology #modelling

bioAffinity scientist Rossella Titone, PhD, and David Elzi, PhD and VP of Product Development, take a break at #CHEST2024 where they are catching up with the latest ground-breaking science and clinical guidance. And, of course, sharing info about CyPath Lung and other products in the BIAF pipeline. #networking #CyPathLung #lungcancer #earlydiagnosis #science #pulmonology

Engineering exosomes for in vivo mouse studies: Stephen Gould at Johns Hopkins Medicine and collaborators developed the Exomap1 transgenic mouse, which, upon Cre recombinase activation, expresses human CD81 fused with mNeonGreen (HsCD81mNG), and before Cre activation, expresses a red fluorescent protein targeted to mitochondria. Their findings suggest that the Exomap1 mouse serves as a valuable resource for in vivo investigations into exosome biology https://lnkd.in/etBgArFm also authored by Francis Fordjour, Ph.D., Sarah Abuelreich, Xiaoman Hong, Emeli Chatterjee, Valeria Lallai, Martin N., Andras Saftics, Ph.D., Fengyan Deng, Natacha Carnel-Amar, Hiroaki Wakimoto, Kazuhide Shimizu, Malia Bautista, Tuan Anh Phu, Ngan (CeCe) Vu, Paige Geiger, Robert L. Raffai, Christie Fowler, Saumya Das, Lane Christenson and Tijana Jovanovic-Talisman #extracellularvesicles #bioengineering #exosomes #superresolution #microscopy #flowcytometry #Vesiculab

𝗩𝗮𝘀𝗰𝘂𝗹𝗮𝗿 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵: 𝗜𝗻𝘁𝗿𝗼𝗱𝘂𝗰𝗶𝗻𝗴 𝗠𝗶𝗰𝗿𝗼𝗳𝗹𝘂𝗶𝗱𝗶𝗰 𝗩𝗲𝘀𝘀𝗲𝗹-𝗼𝗻-𝗖𝗵𝗶𝗽 𝗣𝗹𝗮𝘁𝗳𝗼𝗿𝗺 Prof. Matthias Meier and his team from Helmholtz Pioneer Campus @ Helmholtz Munich developed a cutting-edge microfluidic vessel-on-chip platform. Leveraging human #stemcells is an innovation that promises #PersonalizedMedicine and offers alternatives to animal models. The results were published in Cell Reports (Cell Press). 👉 Learn more in our news:  🔗https://lnkd.in/d7eEyGwV #OrganOnChip #VascularResearch #research

I am thrilled to share our manuscript which is an integral part of my PhD journey, looking into the composition and spatial relationships of cell types in the developing human lung using multiplexed imaging. Grateful for the support of outstanding collaborators and supervisors, Emma Lundberg and Burcu Ayoglu! #SpatialBiology #PhenoCyclerFusion #SpatialOmics doi: https://lnkd.in/d_C8u3w4

What are the biggest challenges facing biomedical engineering today? A team of leaders in the field, including Professor and Head Brenda Ogle recently identified five top challenges in the journal IEEE Open Journal of Engineering in Medicine and Biology:  ✅ Creating avatars of human physiology  ✅ Augmenting human functions  ✅ Engineering the brain and foundations for in vitro modeling  ✅ Harnessing the immune system for health and wellness  ✅ Engineering genomes and cells. Read more: ⬇️ https://bit.ly/3V3FYHW What do you see as the biggest challenges? #biomedicalengineering #bioengineering #precisionmedicine #precisionengineering #tissueengineering #stemcells #medicaldevices #neuralengineering #neuroengineering #neuromodulation #artificialintelligence #immunoengineering #immunotherapy #genomics #genomeengineering #mathematicalmodeling #bioinstrumentation #UMN #medicine

🚀 Exciting news in Liver-Brain Axis research! Thrilled to share our Application Note on the development of an in vitro model of the Liver-Brain Axis using NANOSTACKS™. 👉 Dive into our Application Notes: https://lnkd.in/ey6yvjRY Key Highlights from the Application Note: - Comprehensive protocol for establishing the in vitro model - Functional characterisation of the liver cells HepaRG® included in the model - Significant advancements in recapitulating physiological responses Why NANOSTACKS™? - Cutting-edge technology for precise and reproducible results - Mimic the in vivo microenvironment for authentic cellular responses - Accelerate your research with confidence 📣 Join the conversation! Share your thoughts and questions in the comments. Let's propel liver-brain axis research together! #LiverBrainAxis #NANOSTACKS #ComplexInVitroModel #organonachip #DrugTesting #Revivocell

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