Drug Target Review’s Post

If you are heading to San Diego to the #AACR24, make sure to visit Somalogic booth 3718 to learn more about how Somalogic's technology can help accelerate your research in biomarkers discovery. Marc Gunter and Karl Smith-Byrne will share data from the European Prospective Investigation into Cancer and Nutrition (EPIC) during the AACR. #proteomics #drugdiscovery #drugdevelopment #biomarkerdiscovery

Join us for an insightful webinar led by acclaimed expert Jordi Petriz, well known for his extensive contributions to the fields of flow cytometry and cancer research. This webinar will delve into the capabilities of the Attune CytPix flow cytometer—a breakthrough technology that seamlessly merges standard cytometric fluorescence data with morphometric parameters derived from high-resolution brightfield images of individual cells. Discover how this innovative tool can unravel cell morphology, cell-cell interactions, rare event identification, and disease confirmation, offering a comprehensive analysis that transcends traditional flow cytometry. Explore its applications in cancer research, including circulating tumor cells, cell-mediated cytotoxicity, apoptosis detection, and other biological insights like never before. #thermofisheremp

Advancing Cancer Research with Biotest's Ready-to-Use CRISPR/Cas9 Kits   We are excited to share our latest newsletter with you, featuring cutting-edge advancements in cancer research.  With Biotest's new ready-to-use CRISPR/Cas9 kits, we make it easier for you to streamline molecular biology processes in the lab, helping researchers like you accelerate groundbreaking discoveries. Explore how these tools can aid in the quest for new treatments and therapies, driving progress in healthcare and diagnostics. https://did.li/hmbOf

In CT scans in oncological patients, make your life more easy by assesing low KeV mono-energetic images.

Developing a graphene-based biosensor for ultra-sensitive exosome detection: in this article, Xiaoshuang Chen, YU ZHANG at Shandong University and collaborators developed an innovative electrochemical sensing chip, combining reduced graphene oxide with laser-induced graphene, to detect exosomes linked to breast cancer biomarkers https://lnkd.in/eayui9h3 Their biosensor successfully analysed exosomes in breast cancer cell lines and patient serum, demonstrating its practical value for early disease screening and diagnosis. An article co-authored by Xiaohui Yan, Jiaoyan Qiu, Xue Zhang, Yunhong Zhang, Hongpeng Zhou, Yujuan Zhao and Lin Han #extracellularvesicles #exosomes #biosensor #graphene #tetraspanin #Vesiculab

🔬 Did you know that mitochondria, the powerhouse of our cells, are inherited from our mothers? These tiny organelles are not just crucial for our health but also play a significant role in cancer. Cancer cells rely on mitochondria for energy, especially in harsh environments where nutrients are scarce. Mitochondria help these cells by producing ATP, a more efficient energy source than glycolysis. This process is key for tumor growth and survival. Understanding the intricate dance between cancer cells and mitochondria is vital. It sheds light on how tumors resist drugs and continue to thrive. Learn more about the world of cellular energy and cancer resilience - download the infographic: https://ow.ly/7N9c50Soprv Follow Incucyte® - Live-Cell Analysis Systems to find out more about observing and quantifying complex biological changes in real-time. #SimplifyingProgress #CancerResearch #Mitochondria #CellBiology #Cancer #livecellimaging

Unlock answers to key cancer biology questions by performing single-cell DNA-seq on FFPE samples stored for decades! Access the protocol: https://ow.ly/pyoX50Qp1nL A recent Cell paper published by Drs. Kaile Wang and Nick Navin, “Archival single-cell genomics reveals persistent subclones during DCIS progression,” describes a method that applies the power of the ICELL8® cx Single-Cell System to genomic analysis of archival tumor samples. This exciting work led to a user-generated protocol that you can apply to answer key questions in your own research! #CNV #SingleCell #DNAseq #FFPE #cancer #tumor

Publication Highlight 🔎📖: Very interesting research from our very own Diana Möckel! In this work, she demonstrated that inhibiting the CCL2-CCR2 pathway in a breast cancer mouse model induces vascular normalization and reduced the presence of harmful immune cells, therefore improving drug delivery and effectiveness. The #imalytics was used to analyze three dimensional volume renderings from CT and Fluorescence data for qualitative and quantitative results across multiple time points. Here are some elegant images from the paper; to read the full article, click here: https://lnkd.in/eaMp9cN8

𝗧𝗿𝗮𝗰𝗸𝗶𝗻𝗴 𝗗𝗼𝘄𝗻 𝘁𝗵𝗲 𝗚𝗲𝗻𝗲𝘁𝗶𝗰𝘀 𝗼𝗳 𝗧𝘂𝗺𝗼𝗿𝘀   🎙️#Interview with PI Prof. Markus Diefenbacher: Get to Know our Expert for Lung Cancer at the Institute of Lung Health and Immunity.   With his team, Prof. Markus Diefenbacher aims to decipher the genetic complexity of tumors and to develop innovative therapies against lung cancer.   👉 Check out his interview: https://lnkd.in/dPCUeQZP #interview #research #lung #health #cancer #tumor #ImmuneSystem #LungCancer

Dr. Toghrul Almammadov recently presented his research on activity-based molecular probes (aP) for the visualization and treatment of cancer cells at Istanbul Medipol University's #SABITALKS. He highlighted the advantages of fluorescence imaging and photodynamic therapy (#PDT) in targeting cancer cells with improved selectivity. Dr. Almammadov's work focuses on developing innovative molecular probes and #PDT agents, offering promising advancements in cancer diagnostics and therapy. We extend our gratitude to everyone who attended and invite you to follow us for more updates on upcoming events. #SABITALKS #MedipolUniversity #IstanbulMedipolUniversity #CancerResearch #MolecularProbes #FluorescenceImaging #PDT Toghrul Almammadov Özgecan Ş.