Eleven Therapeutics’ Post

Learn more about a Phase 3 Clinical Trial Launched from Johns Hopkins of NAC for RP Patients in this short podcast!

This week on #BioTechNation, Sam Clark, MD PhD, CEO of Terran Biosciences joins me to talk about their two completely different efforts: 1) Terran's expanded efforts in prodrugs and prodrug discovery, and 2) the transformative potential of psychedelics without the hallucinations. Science tells us they are helpful in treating depression, anxiety, and the traumas of PTSD. Listen now or where ever you listen to podcasts: https://lnkd.in/eCKAZY_i

Check out Patrick Short in a fascinating conversation about how genetics influence the drug development process, the shifting perspectives on personal data usage, and the significance of advancing trust and transparency within the industry. 🧬 Thank you for having us on Beyond the Hype, MMC Ventures! 🙏

What is the holdup in prescribing the most suitable drugs to patients with rare diseases? Here’s William H on the Life Sciences 360 podcast with Harsh Thakkar, discussing the importance of behavioural science in pharma. #lifesciences #podcast #lifesciences360

In a recent pharmaphorum #podcast, web editor Nicole Raleigh interviews our CEO @Neil Weir, discussing his journey from Big Pharma to his role at Sitryx today. Neil sets out what attracted him to Sitryx and why immunometabolism-targeting therapies, like those Sitryx is developing, could hold the key to addressing a range of chronic #autoimmune and #inflammatoryDiseases.   Listen to the podcast here: https://bit.ly/3N33PD7 #lifeSciences #biotech #cellMetabolism #drugDiscovery #drugDevelopment #immunometabolism #biopharma #biotechnology

Our latest podcast on mescaline is out now. #psychedelicscience

This week on #BiotechNation: Are your genes failing you? Noah Davidsohn of Rejuvenate Bio joins me to discuss how regulating protein expression can combat aging and treat diseases like heart failure and diabetes. Listen now or where you download podcasts: https://lnkd.in/gipcGbaV #Genetics #Aging #HealthTech

Why is behavioural science so important? Listen here to find out more

Nature versus nurture!     In the third episode of our podcast "The Longevity Code", we explore the role and interplay of nature and nurture when it comes to longevity and chronic disease with Thomas Szucs, Professor of Pharmaceutical Medicine.   According to Thomas Szucs, this is the question of questions, and he uses a metaphor to illustrate his point:   ► Loading a gun with ammunition is the sum of your genes   ► Pulling the trigger is your lifestyle   Thomas Szucs has years of experience in both academia and industry, making him a leading authority on health economics, policy and management.   His research focuses on the impact of genetic predisposition and how lifestyle choices can influence our health outcomes.   👉 Listen to this episode as we unravel the mysteries of our genes and lifestyle with deep insights from a leading expert in the field! You can find the Links to the current episode as a comment in the attachment.   #longevity #thelongevitycode #podcast

 Questions of the month:  ---  1. What if we could use genetic evolution and modifying the ubiquitin-proteasome pathway for more targeted therapy in proteinopathies, for example utilizing directed evolution and protein engineering with ubiquitin or regions of the proteasome complex, to include antisense mRNA for key motifs apart of amyloid precursor protein (APP), PSEN1 or SNCA? Could we better target the histopathological hallmarks associated with Alzheimer’s disease, such as the plaques of amyloid-beta, that are indicated in Alzheimer’s disease progression? 2.  What if we could use different modified tRNA, or agents in the protein translation pathway, to facilitate therapy for NDD proteinopathies. In reference to question 1, check out this article on the UPS system in the body: The Ubiquitin–Proteasome System in Immune Cells .