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The development of an AI model to enhance tumor removal accuracy during breast cancer surgery is a significant advancement in the field of oncology. The AI model can assist surgeons in accurately identifying and removing tumors, potentially reducing the risk of leaving cancerous tissue behind. By providing real-time guidance during surgery, the AI model may contribute to improved decision-making and surgical outcomes. Tailoring the surgery to individual patient needs based on AI analysis may lead to more personalized and effective treatments. The use of AI can potentially streamline the surgical process, saving time and resources. It's important to note that the success and adoption of such AI models would depend on rigorous testing, validation, and integration into standard medical practices.

We are excited to announce that Optiscan Imaging Ltd has received ethical clearance from the Royal Melbourne Hospital Human Research Ethics Committee to commence an in vivo clinical study focused on breast cancer. This study will showcase the capabilities of our recently unveiled InVue™ precision surgery imaging platform. The InVue™ device will be used during surgeries to collect real-time imaging data of the surgical cavity after tumor removal, aiming to determine the clearance of the tumor on the spot. Optiscan CEO and Managing Director, Dr. Camile Farah, stated: “This non-interventional study design allows us to gather valuable imaging data without interfering with standard care. We anticipate progressing to an interventional protocol, where collected images will guide surgeons in real-time decision-making for optimal patient outcomes.” Stay tuned for more updates as we continue to advance precision surgery and improve patient care. https://lnkd.in/gQz2e2HW #Optiscan #BreastCancer #InVue #PrecisionSurgery #MedicalInnovation #Healthcare

Molecular margins in brain tumor resection. During brain tumor surgery, one daunting task is to surgically preserve as much brain as possible while aiming to achieve clean margins. The wound bed is like a crater and identifying where the crater is still hot is very challenging. Most progression events after surgery are failures within 2cm of the margin and achieving local control is one key element in achieving optimized survival after resection. So-called supramaximal resection strategies can improve local control; however, we do not know which patients benefit from such radical resections. We developed a predictive model (using Lasso regression) to figure out which IDH wild-type GBM tumors could be completely removed during surgery. This model used data from surgery, imaging scans, and genetic tests to better predict how much of the tumor could be taken out. We then investigated whether survival correlated with tumor burden a by analyzing tumor cell content at the surgical margin with a rapid qPCR-based method for detection of the TERT promoter hotspot mutations. Our retrospective radiographic and molecular data driven predictive model had an AUC of 0.83 with a sensitivity of 62% and specificity of 90%. We then prospectively analyzed the model in 44 patients and found 89% were correctly predicted to achieve a resection volume of <4.9cc. Of these 44 prospective patients undergoing rapid qPCR TERT promoter mutation analysis at the surgical margin, 7 had undetectable TERT mutation, of which 5 also had a gross total resection. In these 5 patients at 30 months follow up, 75% showed no progression, compared to 0% in the group with TERT mutations detected at the surgical margin (p=0.02). Surgical margins without detectable TERT mutations correlated with increased progression free survival. We thereby describe a novel approach to apply molecular testing for the rare brain tumor cells at the surgical margin. And, importantly, patients with molecular clean margins after supramaximal resection achieved longer survival with local control.  Brain tumor classification relies on molecular testing and this is a novel use case for molecular testing. link to pubmed: https://lnkd.in/e-Vjzhhh link to publication: https://lnkd.in/exkF8SnT Fantastic teamwork by: Elie Massaad, William Smith, Joseph Bradley, Eric Esposito, Mihir Gupta, Evan Burns, Ryan Burns, Jose Vlarde, Inka Berglar, Rajiv Gupta, Maria Martinez-Lage, Jorg Dietrich, Gavin Dunn, Pamela Jones, Bryan Choi, Albert Kim, Matthew Frosch, Fred Barker, William Curry, Bob Carter MD PhD, Brian Nahed MD, MSc. FAANS FACS, Daniel Cahill, and a big shout out to Ganesh Shankar, MD, PhD for his amazing leadership. Massachusetts General Hospital #Neurosurgery #braincancer #cancer #glioblastoma #moleculardiagnostics #diagnostics #biomarker #molecular #precisiononcology

🔍 Revisiting a Pivotal Study in Rectal Cancer Treatment 🔍 Meta-analysis "Comparison of Survival Among Adults With Rectal Cancer Who Have Undergone Laparoscopic vs Open Surgery" remains a cornerstone in our understanding of cancer surgery outcomes. Authored by Meng Kong, Hongyuan Chen, Keshu Shan, Hongguang Sheng, and Leping Li, this study provides invaluable insights into the long-term benefits of laparoscopic surgery for rectal cancer patients. 📈 Highlight: The study found a significantly better overall survival rate for laparoscopic surgery compared to open surgery, challenging previous concerns and advocating for its routine use. 🎓 Earn 1.0 CME Credit: This analysis not only advances our knowledge but also offers CME credits for healthcare professionals seeking to deepen their expertise. 💡 Let's reflect on how these findings continue to influence surgical choices and patient care strategies in oncology. https://lnkd.in/dXcN_CUU #MedicalEducation #CME #Oncology #RectalCancer #LaparoscopicSurgery #HealthcareProfessionals

Doctors At Apollo Cancer Centre Perform Minimally Invasive Robotic Surgery On Patient With Pseudomyxoma Peritonei In a major medical breakthrough, surgical oncologists at Apollo Cancer Centres (ACC) has successfully performed India's first Robotic Cytoreductive Surgery (CRS) with Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for a peritoneal surface cancer. This minimally invasive, robotic-assisted approach marks a paradigm shift in treating Pseudomyxoma Peritonei (PMP), an aggressive appendix cancer, offering patients with a new standard of care, enabling faster recovery and improved quality of life. Dr. Ajit Pai, Senior Consultant in Surgical Oncology and Robotic Surgery, Apollo Cancer Centre, Chennai along with his team, spearheaded this first-of-its-kind approach. The collaborative clinical expertise and unwavering dedication to transformative tech innovations at ACC, were instrumental in achieving this remarkable success. A female patient, aged 51, was diagnosed with bilateral ovarian masses, and had extensive surgical intervention, including the removal of the uterus, ovaries, appendix, and part of the omentum. Subsequent histopathological examination revealed a high-grade mucinous tumour of the appendix with pseudomyxoma peritonei (PMP), necessitating additional surgery. The patient was found to have residual mucinous implants (gelatinous deposits that remain in the abdomen post-surgery for appendicular mucinous tumors) in the pelvis and around the cecum (first part of the colon). #roboticsurgery #PseudomyxomaPeritonei #cancer #appendixcancer #doctors #ApolloCancerCentre #RoboticCytoreductiveSurgery #HyperthermicIntraperitonealChemotherapy

Clinical Practice Points of Sentinel Node Biopsy in Breast Cancer surgery: a.    SLNB is the standard of care for axillary staging in clinically node-negative breast cancer. We all know that the dual-dye technique (technetium-99m radio-colloid and blue dye combination) is the gold standard technique for identification of SLNs with high detection rates (> 90%) and lower false-negative rates (< 5%-10%). Although the dual dye technique is the gold standard, its penetration in clinical practice is limited, owing to practical problems associated with the blue dye and radio-colloid (ie, licensing, establishment, exposure, and disposal). b.   Optical imaging using the near-infrared fluorescence lymphatic tracer ICG has shown promising results as an alternative for, or an addition to, conventional SLN mapping. There has never been a study with a direct comparison of the standard of care with ICG to see if it could replace the existing standard. c.    In our study, ICG fared better than the dual dye with respect to the SLN identification rate, SLNB sensitivity rate, and false- negative rate, which were 96%, 97.6%, and 3.2%, respectively, for ICG compared with dual dye, which was 94%, 93.2%, and 6.2%, respectively. ICG fluorescence imaging permits real- time visualization of lymphatics and provides an additional dimension to the SLN biopsy that is safe and effective. d.   The above results open up a new Pandora’s box of opportunity for developing countries with limited resources and second-tier centers of developed countries to perform SLNB for node-negative early breast cancer where there is limited access to nuclear medicine facility, thus replacing the standard of care with ICG. Source: "Can Low-cost Indo Cyanine Green Florescence Technique for Sentinel Lymph Node Biopsy Replace Dual Dye (Radio-colloid and Blue Dye) Technique in Early Breast Cancer: A Prospective Two-arm Comparative Study" Dr S.P. Somashekhar et al https://lnkd.in/g6c3h8FU www.irillic.com

March is Colorectal Cancer Awareness Month. The second leading cause of cancer death in the United States today is colorectal cancer, and approximately 150,000 people in the US will be diagnosed with the disease this year. The Vattikuti Foundation applauds robotic surgeons like Dr. Somashekhar SP, Dr. Kushal Agrawal, and the team from Aster International Institute of Oncology, Aster Hospital who have found ways to preserve nerve functionality for patients undergoing surgery for colorectal cancer. Surgical methods in the past commonly resulted in a high incidence of organ dysfunction, which severely compromised patient quality of life with complications such as low anterior rectal (LAR) syndrome and urogenital dysfunctions due to intraoperative inadvertent pelvic autonomic nerve damage after rectal cancer surgery. In their video submitted for KS International Innovation Awards 2023, the team from Aster Hospital discusses the current understanding of anatomy, key zones at risk of nerve injury and our experience with robotic platform in rectal surgery. Open call to innovative colorectal robotic surgeons: now's the time to prepare a video with your successful and innovative ways of using technology to help patients beat colorectal surgery. Your 8-minute electronic submission can be entered in the KS International Innovation Awards 2024 competition beginning April 15, 2024. Here is the link to the surgical video: https://lnkd.in/damNmg9Q Dr Kushal Agrawal Aster DM Healthcare ASTER MEDCITY Dr. Somashekhar S P Raj Vattikuti Mahendra Bhandari #colorectalcancer #colorectalcancerawareness #colorectal #roboticsurgeon #roboticsurgery #Surgery #surgeons #robotics #roboticschallenge #roboticsinnovation #KSAwards2024 #vattikutifoundation

Read about how Perimeter Medical Imaging AI is using AI to help surgeons remove all breast cancerous cells on the first surgery. #AI #healthcareinnovations

Robotic-assisted radical prostatectomy (RARP) has indeed revolutionized the treatment of prostate cancer. It utilizes advanced robotic systems to assist surgeons in performing the procedure with greater precision and control. Here are a few reasons why RARP is considered beneficial for prostate cancer patients: 1. **Minimally Invasive**: RARP is a minimally invasive procedure, which generally means smaller incisions, less pain, and a quicker recovery compared to traditional open surgery. 2. **Precision**: The robotic system provides surgeons with enhanced dexterity and precision, which is crucial for navigating around delicate and complex anatomical structures. 3. **Reduced Blood Loss**: Patients often experience less blood loss during robotic surgery, reducing the need for transfusions. 4. **Shorter Hospital Stay**: Due to its minimally invasive nature, patients often have shorter hospital stays and can return to normal activities more quickly. 5. **Potential for Better Outcomes**: Some studies suggest that RARP may lead to better cancer control, with lower rates of positive surgical margins. This can mean a decreased likelihood of cancer recurrence. 6. **Improved Visuals**: The robotic system provides high-definition, 3D visuals that help surgeons operate more effectively. 7. **Reduced Risk of Complications**: There's often a lower risk of complications such as infections and scarring. 8. **Enhanced Recovery of Functions**: Many patients experience quicker recovery of urinary and sexual functions compared to traditional approaches. While Robotic-assisted radical prostatectomy offers these significant advantages, it's important for patients to have a thorough discussion with their healthcare provider regarding the risks, benefits, and appropriateness of the procedure for their individual condition.

📃Scientific paper: Postoperative breast cancer surveillance: Can contrast-enhanced spectral mammography solve the diagnostic dilemma? Abstract: Background For women worldwide, breast cancer is considered a significant public health concern. The development of enormous changes caused by surgery and irradiation makes diagnosing the postoperative breast a complicated procedure. The current study aimed to detect the additive role of contrast-enhanced spectral mammogram (CESM) to digital mammogram and US in the surveillance of postoperative breast cancer patients. Methods This research was conducted on 74 female patients with a prior history of surgery for the treatment of previous breast cancer. All patients had undergone sonomammography and CESM. Benign lesions were followed up, while suspicious lesions were biopsied. Results The current study revealed that CESM can enhance the sensitivity, specificity our overall accuracy of sonomammography in the surveillance of breast cancer patients after surgery. Conclusion Adding CESM to properly selected patients in the surveillance of breast cancer patients after surgical treatment can enhance the diagnostic performance of conventional imaging modalities. Continued on ES/IODE ➡️ https://etcse.fr/RGiwB ------- If you find this interesting, feel free to follow, comment and share. We need your help to enhance our visibility, so that our platform continues to serve you.