Gain Therapeutics’ Post

Navigating the complexities of the term 'Rainmaker' with Gene Valdez! 💦 Learn the origins, debunk misconceptions, and understand why it matters. Insights shared at www.ceo2rainmkr.com. Book your call for clarity! 🌐💼 #RainmakerClarity #CEO2Rainmaker #BusinessInsights

Join me, Gene Goldman, CFA, and Peter Reardon, AIF® on Thursday at 10AM for our Webinar “Navigating the Market: Portfolio Impacts for 2024.” Learn more below! Register for the webinar here: https://lnkd.in/gRv2cSYc #reachyoursummit #pathtothesummit

Negotiation tip of the week: Put down your cell phone and listen carefully. Use both critical listening (looking for holes in your negotiating partner’s logic) and empathetic listening (building rapport). #negotiation #negotiationskills #business Gene Killian

John Cutlers recently talk with Gene Kim reminded me of the great book; Wiring the winning organization and the earlier podcast; The Idealcast. So much inspiring content. This metaphor about Steve and Gene moving a couch is great in so many ways. (Transcript from their recent talk) Gene: And so you might think that this is all brawn work, no brain work allowed. And yet, you know, there's actually a whole bunch of problems that don't have obvious answers, like, you know, where's the center of gravity, to get through a narrow doorway around which axis do they rotate? And, you know, to get through a narrow winding staircase, who goes first, do they face forwards or backwards? And of course, they don't need consultants or focus groups, right? Just by picking up the couch, fast [00:02:00] trial and error, um, but most importantly, communication coordination, we can have some confidence that Steve and Gene will be able to achieve what they want to do. But there are all these things that we can do as leaders to make their work more difficult. We can turn off all the lights, right? Which makes the work take longer. They can actually, uh, hurt the furniture, hurt themselves. But there's another thing that leaders can do, um, you know, such as introducing a lot of, uh, noise, loud music, or even introducing an intermediary, where Steve and Gene can no longer talk directly with each other. They have to go through work orders, JIRA, tickets, you know, account managers, lawyers, so forth. Suddenly under those conditions, we can imagine scenarios where they will not be able to achieve their goal. So it's so interesting, right? We haven't changed the nature of the couch. We've actually changed what we call the Layer 3 wiring. And so I think the couch is such an interesting metaphor because it really embodies two very important concepts. Coherence. To what degree can Steve and Gene work as a coherent and unified whole? And coupling, right? They are inherently coupled to each other through the couch.

The American Cytogenomics Confernce has been such a wonderful meeting to attend and it's been so valuable connecting with our cytogenetics community and learning about all the new technology and methods emerging. #Cytogenetics #Kromatid #Genomics #StructuralVariations #Karyotyping #Chromosome

In Episode 4 of the Station 4 Negotiation Podcast, we took a look at the tense negotiations that got the world out of the extremely dangerous Cuban Missile Crisis. Please give it a listen (and give the Podcast a follow). One lesson: Always leave the other side a way to save face. #negotiation #negotiationtips #negotiationstrategies

What is the correct shear force position in a pinned connection, and how does it affect the joint behaviour? Join my colleague Gene Vallente this Thursday, August 8, for the third webinar from the IDEA StatiCa Master your connections series. Learn why stiffness is crucial and what the options for shear (pinned) connection design are. 🕐 When? Thursday, August 8th, 1 PM (30 minutes session) SGT (UTC +8) Register for the webinar for FREE here: https://lnkd.in/eEta_7_S #ideastatica #cbfem #steelconnections #pinnedconnections #shearconnections #structuralengineering

How do you negotiate effectively in high-pressure, high-risk situations? How do you keep a cool head when everyone else in the room is pushing for aggressive action? EPISODE 4 OUT NOW. Find your listening platform: https://lnkd.in/eXadRZM3 Gene Killian #negotiationtraining #negotiationskills #negotiation #disputeresolution

It’s a random walk down Wall Street (thanks Louis, Paul, Gene, Paul 2, and Burt). To understand randomness, you must understand Pascal’s Triangle, Galton’s Board, the Binomial Distribution, Independent Identically Distributed (IID) random variables, and the gambler’s fallacy (look them up on Wiki) and also see below. If you don’t speak Riskese, you better find someone who does. Odds are you don’t know what the odds are. See here: https://lnkd.in/g7sSwgFQ

N-nitrosodimethylamine (NDMA) has been identified as a contamination impurity in some commonly used pharmaceuticals, and this has resulted in several drug recalls by regulatory authorities. To improve evidence-based risk assessment, more experimental data is required to understand the link between NDMA exposure, mutation frequency and the sequence of events which may lead to the adverse outcome of carcinogenesis. I’m very pleased to have contributed along with other authors to this recent open access publication. From a pathology perspective, one point of interest was comparing the NDMA-related increased incidence of Ki67-positive hepatocytes, evaluated using a Halo AI-phenotyper model and the increase in mitoses evaluated manually across the different treatment groups. Thanks to @DeonHildebrand for expert help developing the Halo image analysis algorithm!