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👀Probe-based confocal laser endomicroscopy: Vaporized perfluorocarbons deactivate NLRP3 inflammasomes via the HO-1/NRF1 pathway and can alleviate acute lung injury induced by seawater-drowning! #nrf1 #ho1 #lung #physiology https://loom.ly/Y16ADGM

In a recent highlight from our webinar, "Unlocking Genetic Causes of Sudden Cardiac Death with Scalable Assays of Variant Effect," Dr. Victoria Parikh provided an insightful answer to an important question about utilizing assays of variant effects To hear Dr. Parikh's response and explore more about how scalable assays are transforming our approach to cardiac genetics, click the link to view the entire session. Don't miss these expert insights into advancing precision medicine in cardiology! Watch the Full Webinar Here: https://lnkd.in/d5BFGbn3 hashtag #CardiacGenetics #PrecisionMedicine #Webinar #MAVEvidence #ConstantiamBiosciences

In a recent highlight from our webinar, "Unlocking Genetic Causes of Sudden Cardiac Death with Scalable Assays of Variant Effect," Dr. Victoria Parikh provided an insightful answer to an important question about utilizing assays of variant effects To hear Dr. Parikh's response and explore more about how scalable assays are transforming our approach to cardiac genetics, click the link to view the entire session. Don't miss these expert insights into advancing precision medicine in cardiology! Watch the Full Webinar Here: https://lnkd.in/d5BFGbn3 #CardiacGenetics #PrecisionMedicine #Webinar #MAVEvidence #ConstantiamBiosciences #polygenicconditions

Yet another study demonstrating how physiologically unsound it might be to directly attribute the resting slow flow (outside post-pci or ACS setting) to CMD! https://lnkd.in/d3UCntqt, confirming the previous report from King's College Coronary physiology group( https://lnkd.in/dEc8mQg4) We hope to share the results of an intriguing hemodynamic analysis seeking for the mechanistic explanation for this phenomenon soon Murat Sezer Peter Damman Yaren Alan

🔬Unlocking new frontiers in #CardiologyResearch! Our latest article in Exploration of Cardiology reveals groundbreaking findings: SGI-1027-loaded nanoparticles effectively reduce atherosclerosis in mice and curb inflammation in human macrophages.  A game-changer in epigenetic therapy!  🧬 #Atherosclerosis #Nanotechnology #Epigenetics" 🔗https://lnkd.in/gu9J2d-c

The cumulative evidence available indicates that there can be a prognostic benefit from revascularization in chronic coronary syndrome patients, provided there is significant ischemia, as demonstrated by either imaging or coronary physiology. Trials that have effectively met this criterion consistently demonstrate a reduction in rates of spontaneous myocardial infarction, which holds both prognostic and clinical significance. The prognostic benefit of revascularization in patients with heart failure with reduced ejection fraction remains especially problematic, with a single contemporary trial favouring surgical revascularization. The very recent publication of a trial focused on revascularizing non-flow-limiting "vulnerable" plaques adds further complexity to the field. The ongoing debates surrounding revascularization in chronic coronary syndromes emphasize the importance of personalized strategies. Revascularization, added to the foundational pillar of medical therapy, should be considered, taking into account symptoms, patient preferences, coronary anatomy and physiology, ischemia tests and intra-coronary imaging.

The abstract outlines the evolving management of cardiogenic shock, highlighting the transition to using temporary mechanical circulatory support (t-MCS) like IABP, VA-ECMO, Impella, and ECPELLA, informed by advances in circulatory physiology. #CardiogenicShock #MCS #VAD

The abstract outlines the evolving management of cardiogenic shock, highlighting the transition to using temporary mechanical circulatory support (t-MCS) like IABP, VA-ECMO, Impella, and ECPELLA, informed by advances in circulatory physiology. #CardiogenicShock #MCS #VAD

We see a need for imaging based biomarkers to assess progression of liver fibrosis in patients with Fontan. In patients with Fontan, elevated liver stiffness doesn’t necessarily mean or correlate with fibrosis. In our preliminary study, ultrasound based spleen stiffness also did not correlate with biopsy-determined scoring of liver fibrosis in patients with Fontan physiology. https://lnkd.in/eBk3wSiW

T-wave inversion is one of the most confusing image changes in the ECG because many diseases cause changes in T-wave inversion. Existing ECG (blue waveform): shows that only the T wave is inverted. You cannot recognize in which disease the T wave is inverted. New ECG (saahECG) black waveform - showing ST segment > 150ms, is an ischemic disease caused by CA vessel stenosis or blockage. - Scientific article published in the International Journal of Cardiology in 2016 - 15 million clinical trials completed in 6 countries in 2015 - 53 US & International patents obtained PhysioSign USA #ecg #noninvasive #ep #cardiology #electrophysiology #ai #electrocardiogram #innovation #medtech #heartdisease #heartattack #coronaryarterydisease #cardiovasculardisease #heartfailure #ptca #cag #stent #pci #pacemaker #ablation