For Fabrece Roup, collaboration isn't a buzzword. It's an integral part of his job as a researcher. Hear why this particular value speaks to him, and how the diverse sets of skills, knowledge, and creativity at Janux inspire and motivate him to achieve more each day to address the unmet needs of cancer patients. #Culture #CoreValues #science #LifeAtJanux #collaboration #oncology #cancer
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Unlocking New Perspectives: Join Evan Hoecht on Day 2 of #PIC2024, May 30th, 6:30pm, as he presents: "Looking At Cancer Differentl: In Vivo Imaging." Don't miss this innovative presentation after Session #5 talks: https://lnkd.in/gygc_T2F #Cancer #CancerResearch #Oncology #Preclinical #PreclinicalImaging
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Chief Medical Officer at CLEARA Biotech BV, leading clinical development, translational science and medical affairs in oncology projects
Novel and exciting data from Cleara Biotech B.V.'s research portfolio were presented yesterday by Diana Putavet at the AM poster session of the American Association for Cancer Research 2024 meeting in San Diego. The presentation summarized the effect of a proprietary peptide that profoundly disrupts FOXO4-p53 binding in preclinical models of triple-negative breast cancer (TNBC). The agent's highly innovative MOA pertains to siphoning peptide-bound p53 thus inducing apoptosis. The effect is specific to cancer cells that have undergone 'scarring' post-cell stress. These cells are highly malignant, resistant to standard therapies, and hyperproliferative, despite their SASP phenotype. Metastatic lesions in both humans and rodents are highly enriched in scarred cells, across assorted histologies, with key tumor types - among others- being TNBC, high-grade serous ovarian Ca and GI malignancies. Of note, the potent proapoptotic effects of CLEARA's peptides on the growth of scarred cancer cells in various preclinical models (both in vitro and in vivo) are independent of the transcriptional activity status of the p53 target, or the presence vs absence of p53 mutations. Our international cross-functional team, led by Peter de Keizer in Utrecht, NL is poised to complete the set of fundamental preclinical experiments on CLEARA's flagship asset, CL04183, within the year. I am excited and honored to be leading the plans for entry of this very promising potentially best-in-class agent in the clinics, supported by an enlarging network of clinical and translational scientific leaders both in the EU and US. For more information on CLEARA, please visit: www.clearabiotech.com. #apoptosis #tp53 #foxo4 #cancer #tnbc #breastcancer #clinicaltrials #IND #CTA #celldeath #cancercell #cellbiology #oncology #cancerresearch #translationalmedicine #mutation #metastasis #resistance #targetedtherapy #chemotherapy #xrt #radiotherapy #aacr24
With a background in cancer research, working on drug development within a utrecht-based biotech startup
Had a great time yesterday at AACR, where I shared my research on breast cancer and had insightful discussions with fellow attendees. This work wouldn't have been possible without the invaluable contributions of Marjolein Baar, Esmée Bouma, Johannes Lehmann, and Peter de Keizer. #research #networking #clearabiotech #umcutrecht
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Listen to an #audio reading of a #pressrelease about this #research paper: “Cyclin D1 expression in penile cancer." https://lnkd.in/edxFDE2x #trendingwithimpact #cancer #penilecancer #openaccess #publishing #podcast #soundcloud
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One of the best quick reference texts to use by Dr. Akira Kawai - Herbert Loong, MBBS FRCP FASCO https://lnkd.in/eGpwbtyT National Cancer Center Hospital The Chinese University of Hong Kong #Cancer #CUHKSarcoma #MedOnc #OncoDaily #Oncology
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📢📰 This study, published in International Journal of Molecular Sciences, elucidates multiple synergistic pathways contributing to this enhanced therapeutic effect. READ➡️https://lnkd.in/eXBVfADV #oncology #oncologyresearch #hematology #cancer #cancerresearch
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Uncover the stages of AI integration, from diagnostic support to humanoid robots Dr. Fabio Ynoe de Moraes Queen's University https://lnkd.in/e2J9ge2X #Cancer #OncoDaily #Oncology #PatientCare #CancerTreatment
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It was fascinating to learn about the incredible work of Arturo LoAIza-Bonilla MD and Massive Bio using AI to advance cancer care. Article written for Strategies Oncology Magazine. #cancer #cancercare #clinicaltrials #cancertreatment #oncology #artificialintelligence #aitechnology #massivebio #writer #magazine
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🚀 Excited to share our latest #article titled “A systematic review of machine learning-based tumor-infiltrating lymphocytes analysis in colorectal cancer: Overview of techniques, performance metrics, and clinical outcomes”! In this piece, we reviewed traditional #machine_learning and #deep_learning models conducted to analyze TILs on colorectal #cancer whole-slide images. Whether you are an expert in #computational_pathology or just starting out, I believe there is something interesting for everyone. 😊 Dive into it and share your thoughts with us. Read more: https://lnkd.in/eBTmeDQr
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What's a fast way to get to all of the My Density Matters Resources? What about the Breast Cancer Screening Guide, Check Your Chart, additional screening modalities, downloads, etc... It has never been easier! Find links to everything here: https://lnkd.in/gwCwuJYF #mydensitymatters #checkyourchart #Linktree
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#AACR24 count down mode! Cancer Cell will be represented by Steve Mao and myself. Let’s talk about your exciting #cancerresearch and #oncology research. See you soon! 📷: AACR
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