Kate Midden’s Post

AccendoWave - A Pain #Data Company Women are not small men. That may sound obvious, but too often that idea has informed health care, with male physiology the default for research and treatment. From the earliest phases of testing and clinical trials on animals, models have historically been based on male specimens. Questions about sex-based differences were rarely investigated or recorded, with the assumption that other than reproduction, there were few important differences in how organs and biological systems functioned. 80% of Pain Research - Human Men & Male Mice. A Top 4 Global Health Equity Solution and Top 15 Global Remote Monitoring Company, AccendoWave, benchmarks objective brain wave pain data (specialty, gender, age) and has nine #pain databases: Emergency Department, Maternal Health, Oncology, MSK, Medical Surgical, ICU, Women, Adults, Seniors to eliminate bias, improve outcomes and reduce health care costs. If desired, AccendoWave can also create customized pain databases for partners that can be accessed on the Datavant platform.

AccendoWave - A Pain #Data Company #Women spend 25% more of their lives in debilitating health than men, according to a report from the World Economic Forum and the McKinsey Health Institute. The women's health gap includes a persistent #data gap, with women being under diagnosed for certain conditions compared to men. A Top 4 Global Health Equity Solution and Top 15 Global Remote Monitoring Company, AccendoWave, benchmarks objective brain wave pain data (specialty, gender, age) and has nine #pain databases: Emergency Department, Maternal Health, Oncology, MSK, Medical Surgical, ICU, #Women, Adults, Seniors to eliminate bias, improve outcomes and reduce health care costs. If desired, AccendoWave can also create customized pain databases for partners that can be accessed on the Datavant platform.

AccendoWave - A Pain #Data Company Women spend 25% more of their lives in debilitating health than men, according to a report from the World Economic Forum and the McKinsey Health Institute. The women's health gap includes a persistent data gap, with women being underdiagnosed for certain conditions compared to men. Here’s what you need to know about the women’s health gap – and six conditions that highlight it. Top 4 Global Health Equity Solution and Top 15 Global Remote Monitoring Company, AccendoWave, benchmarks objective brain wave pain data (specialty, gender, age) and has nine #pain databases: Emergency Department, Maternal Health, Oncology, MSK, Medical Surgical, ICU, #Women, Adults, Seniors to eliminate bias, improve outcomes and reduce health care costs. If desired, AccendoWave can also create customized pain databases for partners that can be accessed on the Datavant platform.

Reducing the women’s health gap improves lives and can potentially unlock a $ 1 trillion GDP opportunity annually by 2040, according to a new analysis from the World Economic Forum in collaboration with the McKinsey Health Institute. Together, they reveal the incredible avenues for creating meaningful global change. Historically, men have led and been the subject of the study of medicine and biology. Most animal models have been done on male specimens, which still prevails today. Questions around sex-based differences were rarely investigated or recorded, with the assumption – now known to be false – that there are few important differences in the functioning of organs and systems in men and women beyond reproduction. This has resulted in ~65% of interventions (which have sex-disaggregated research) being less effective for women than men https://lnkd.in/d6FqexVu

Exciting news was announced yesterday when the White House announced $100m in dedicated funding for women’s health. While helpful in overcoming some of the health disparities faced by women, it’s not enough for a few reasons: Consider that a study in 2020 estimated that the average cost of getting one new drug into the market was $1.3 billion. (This number was much lower compared to previous studies, which have placed the average cost of drug development as $2.8 billion). Women represent the majority of Alzheimer’s patients and our cardiovascular health is worse than men. Work in these diseases is very expensive. There are still inadequate treatments for women’s health conditions, such as endometriosis and autoimmune conditions. $100m is minimal in comparison to the realistic investment needed to noticeably advance women’s health research. $100m is a small percentage of the total annual NIH budget, which is over $46B. The rounding error is being thrown to women to grab headlines and get votes, but not to make serious change. Recent state actions, such as recent rulings in Alabama on the status of frozen embryos and the resulting discontinuation of IVF services by some hospitals, cause significant harm to women’s health, which is not mitigated by the increased funding. More needs to be done with a comprehensive view of all of the ways in which US women are disadvantaged when it comes to their health. We need a serious commitment and should not be bought so cheaply. #womenshealth #equitableaccess

75 million years lost until 2040 There is a health gap between men and women, globally. Until 2040, women will spend 75 million MORE years than men in degrees of disability. By closing the health gap by 2040, the eqivalent of 137 million women would access full time positions, pumping $ 1 trillion into economic productivity. The report “Closing the Women’s Health Gap: A 1$ trillion Opportunity to Improve Lives and Econmies” McKinsey Health Institute and World Economic Forum presents data on the health gap and explains how it impacts women, families and society. We don’t know how many of the 75 million years that vaginal infections count for but Gedea Biotech AB aim to limit the disability caused by vaginal infections. We want women to have access to a reliable solution that is safe and effective, minimizing the impact of vaginal infections on daily life. #femtech #womenshealth #gedeabiotech Read the full report here https://lnkd.in/gfP-2Vsa

Collaboration not competition – that is what will improve outcomes in our field. That’s why on the evening of this #WomensHealthWednesday I want to highlight another report highlighting the challenges, needs, and impact of Women’s Health from (admittedly competitor) Accenture and Springboard Enterprises – "State of Women’s Health" https://lnkd.in/eWc4H6p4 I particularly thought their section called “Under-Researched” was critical to highlight. What are the implications of women being under-represented in clinical trials? Well actually monumental! By now – many know that prior to 1993 women weren’t even mandated to be included in clinical trials. This report shows however, that even over the last 5 years, female representation in clinical trials tends to be 12-27% lower than disease prevalence for each condition (see image below). The report goes on to show a case study of the implications – it took dozens of years and many clinical studies to lower the recommended dosage of sedative zolpidem, which had been causing cognitive deficit in women. Just like children are not small adults, women are not smaller men. Women metabolize drugs differently. Not only that – women metabolize drugs differently throughout the month due to our changing hormonal profile. I love companies like Levana.ai and their fearless leader Dr. Ilana Kwartin that are seeking to uncover these trends and enable providers to modulate care based on these findings. The future of Women’s Health must be personalized. What did you find most impactful?

Addressing the disparities in women's health has the potential to extend and improve the quality of life for women globally and significantly boost the global economy by an estimated $1 trillion annually by 2040. Yet, the women's health gap continues to be an industry issue. Here are 4 Underlying Causes of the Women's Health Gap 👇 1. Science 🔬: Traditional studies of human biology often focus on the male body, leading to a limited understanding of sex-based biological differences. This results in fewer and less effective treatments specifically designed for women. 2. Data 🔢: The health issues affecting women are frequently underestimated, with many datasets excluding or undervaluing critical conditions that predominantly affect women. 3. Care Delivery 👩⚕️: Women frequently encounter barriers to accessing care, experience delays in diagnosis, and often receive suboptimal treatment compared to men. 4. Investment 💰: There has historically been less investment in health conditions that primarily affect women, perpetuating a cycle of inadequate scientific understanding and insufficient data to support new investments. Together, we can close the health gap by prioritizing research, enhancing data collection, and improving care delivery, leading to better health outcomes and economic growth. https://lnkd.in/gZKa2xZ3 #palomahealth #hypothyroidism #hashimotos #thyroidcare Insights from McKinsey Global Institute

While it is not good news that investment in #femtech slid from $2.1B in 2021 to $283M in 2023, there does seem to be increasing support for 2024. (To be fair, all #digitalmedicine funding dropped significantly since 2020, although the percent dedicated to womens health in relation to overall funding is much smaller than in 2020.) There are some encouraging products that address #womenshealth (and not just women only diseases!). I'm looking forward to watching what is emerging. #health #patientcare #digitalhealth #medicaltools #womenandgirlsinscience #womentechsters #womeninvestors https://lnkd.in/eVDcvnrd

Neglecting women's health innovations and access is costly, not just for women. According to the latest Closing Women's Health Gap report from World Economic Forum & McKinsey Health Institute: - Addressing the women’s health gap could potentially boost the global economy by at least $1 trillion annually by 2040. - Women spend 25% more of the lives in debilitating health. No geographic region or age group is unaffected. Recommended five-pronged action across multi-stakeholders: 1. Invest in women's centric research. 2. Systematically collect sex and gender specific research data. 3. Increase access to women-specific care in all areas from prevention to treatment. 4. Create incentives for investment in women's health innovation. 5. Implement policies supporting women's health. ProSeek Bio aims to contribute to better women's health through cancer screening tests, starting with ovarian cancer. Our mass spectrometry-based glycoform-specific biomarker platform is pathology lab-ready, allowing rapid implementation after machine learning algorithm development. We will soon be looking for passionate and skilled team members, advocates and networks. Reach out if interested! #biomarkers #cancerscreening #diagnostics #proteomics #massspec #ovariancancer #womenhealth https://lnkd.in/edNrCEqm