Locus Fermentation Solutions’ Post

“So Huber, WTH even is a biosurfactant?” Well, I’m glad you asked! Clearly it’s got a cool molecular structure. And that means it does cooler things than a traditional or “bio-based” surfactant. If you really want to get into the details and benefits, let’s talk!

We believe one-size-fits-all solutions don't cut it. That's why we develop optimized biosurfactant technologies tailored to specific #mineralprocessing needs. Here's a look at the molecules that drive the science, courtesy of our parent company, Locus Fermentation Solutions.

Biocatalysts, often in the form of enzymes, are biological molecules that drive chemical reactions in living organisms. These remarkable catalysts play a vital role in numerous biological processes and find extensive applications across various industries. Enzymes are highly specific, three-dimensional structures that catalyze reactions by binding to specific substrates at their active sites, facilitating the conversion of substrates into products. One of the key advantages of biocatalysts is their unparalleled specificity, allowing them to catalyze reactions with remarkable precision. This specificity arises from the complementary shape and chemical properties of the enzyme's active site and the substrate molecules. Biocatalysis offers significant advantages over traditional chemical catalysts in terms of efficiency, selectivity, and sustainability. Enzymes operate under mild conditions of temperature and pH, which are often compatible with biological systems. This mild reaction environment not only reduces energy consumption but also minimizes unwanted side reactions and the generation of hazardous byproducts. Additionally, biocatalytic reactions typically proceed with high selectivity, producing the desired products without the formation of unwanted byproducts. This selectivity is crucial in industries such as pharmaceuticals, where the production of pure compounds is essential. The versatility of biocatalysts extends across various industries, including pharmaceuticals, food and beverage, agriculture, environmental remediation, and bioenergy. In pharmaceutical synthesis, enzymes are employed in the production of drugs and drug intermediates with high purity and efficiency. In the food industry, enzymes are used to improve food texture, flavor, and nutritional value. Enzymes also play a crucial role in environmental engineering, where they are utilized in wastewater treatment, bioremediation of contaminated sites, and the production of biofuels from renewable resources. Moreover, biocatalysts offer promising solutions in the quest for sustainability. Their renewable nature, biodegradability, and minimal environmental impact make them attractive alternatives to traditional chemical catalysts. With advances in enzyme engineering and bioprocess optimization, the potential applications of biocatalysis continue to expand, offering innovative solutions to engineering challenges and contributing to a more sustainable future. #biocatalys #biocatalysis #bioprocess #chemicalengineering #decarbonization #engineering #sustainability

PRODUCTION OF A BIOSTIMULANTS THROUGH AN ENZYMATIC PROCESS FROM AN AGRO-INDUSTRIAL ORGANIC BY-PRODUCT. Product with high absorption and high potential as a bioproduct/biofertilizer/biostimulant #agrisciences…#research for new biofunctional molecules…

Want to reduce costs in bioprocesses? TRY harder! 💪🏻 No no, I don't mean you should try harder, but T-R-Y the yeast out of it! ⚗️ 📉 This article goes into the economic aspects of microbial fermentation processes used in industrial biotechnology. It emphasizes the importance of evaluating production costs through the metrics of Titer, Rate, and Yield (TRY) before scaling up processes for commercial production. 📈 #TRY Metrics Titer, Rate, and Yield are essential for evaluating the economic feasibility of #MicrobialFermentation, measuring product concentration, formation speed, and substrate conversion efficiency. 💰 Production Costs Optimizing these metrics significantly impacts the cost-effectiveness and scalability of #BiochemicalProduction, with yield improvements notably reducing raw material expenses. 🏭 Industrial Applications TRY metrics are pivotal in producing vital industrial biochemicals such as 1,3-propanediol and ethanol, which are foundational in manufacturing products from plastics to #biofuels. Advancements in #MetabolicEngineering and process design are crucial for improving TRY metrics, offering potential for more competitive bio-based production methods. You can also use Reocto to TRY your #bioprocesses, and make #ScaleUp more efficient! Enhanced microbial production efficiencies could lead to sustainable biofuel alternatives and more eco-friendly consumer products, and even #NovelMedicine, potentially lowering costs and environmental impacts. The article: https://lnkd.in/dg-98GeP

📢 Exciting News! Our latest research article titled “Ionic Liquids toward Enhanced Carotenoid Extraction from Bacterial Biomass” has been published in the journal Molecules! In this study, we explored the use of ionic liquids to improve carotenoid extraction from Gordonia alkanivorans strain 1B, a bacterium known for producing valuable pigments. Our new method boosts extraction efficiency by 264%, while reducing processing time and energy consumption. This breakthrough could pave the way for more sustainable carotenoid extraction in industries such as pharmaceuticals, food, and cosmetics. I would like to extend my heartfelt thanks to the incredible team at LNEG. It’s truly gratifying to contribute to science and be part of a project that has the potential to reduce environmental impact while advancing innovation. Check out the full article here: https://lnkd.in/dYNtAubx #Research #IonicLiquids #Sustainability #Biotechnology #Carotenoids #GreenChemistry #MDPI

𝗔 #𝗳𝘂𝗻𝗴𝘂𝘀 𝗰𝗼𝗻𝘃𝗲𝗿𝘁𝘀 𝗰𝗲𝗹𝗹𝘂𝗹𝗼𝘀𝗲 𝗱𝗶𝗿𝗲𝗰𝘁𝗹𝘆 𝗶𝗻𝘁𝗼 𝗮 𝗻𝗼𝘃𝗲𝗹 #𝗽𝗹𝗮𝘁𝗳𝗼𝗿𝗺 #𝗰𝗵𝗲𝗺𝗶𝗰𝗮𝗹: The fungus #Talaromyces #verruculosus can produce the chemical #erythro-#isocitric #acid, which has received little attention on the market to date, directly from cheap plant waste and thus make it interesting for industrial utilization. Using the natural abilities of the non-genetically modified fungus, a research team from Jena has discovered a method for the efficient conversion of cellulose into a form of isocitric acid. The new production method could significantly simplify the previously complex and multi-stage process for obtaining platform chemicals from cellulose by requiring only a single bioprocess. Thanks to the new cost-effective method, the rarely utilized sister molecule of the intensively used citric acid can benefit a sustainable circular economy – provided there is a market for it. The study was published by a research team from the Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute (Leibniz-HKI) in the journal ACS Sustainable Chemistry & Engineering. 𝗔 𝗻𝗲𝘄 𝗽𝗿𝗼𝗰𝗲𝘀𝘀 𝗳𝗼𝗿 𝘁𝗵𝗲 𝗺𝗮𝘀𝘀 𝗽𝗿𝗼𝗱𝘂𝗰𝘁𝗶𝗼𝗻 𝗼𝗳 𝗲𝗿𝘆𝘁𝗵𝗿𝗼-𝗶𝘀𝗼𝗰𝗶𝘁𝗿𝗶𝗰 𝗮𝗰𝗶𝗱 𝗳𝗿𝗼𝗺 𝘄𝗮𝘀𝘁𝗲 𝗰𝗼𝘂𝗹𝗱 𝗺𝗮𝗸𝗲 𝘁𝗵𝗲 𝘀𝘂𝗯𝘀𝘁𝗮𝗻𝗰𝗲 𝗶𝗻𝘁𝗲𝗿𝗲𝘀𝘁𝗶𝗻𝗴 𝗳𝗼𝗿 𝗶𝗻𝗱𝘂𝘀𝘁𝗿𝘆 𝗶𝗻 𝘁𝗵𝗲 𝗳𝘂𝘁𝘂𝗿𝗲: https://lnkd.in/eDhs9vJJ Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie - Hans-Knöll-Institut, American Chemical Society, Ivan Schlembach, Bettina Bardl, Lars Regestein, Miriam A. Rosenbaum

Is Tylenol an environmental headache? Is there a greener path to our aches and pains? 💊 Did you know that acetaminophen or paracetamol- the active ingredient in the ubiquitous pain relieving medicine - is produced industrially by turning benzene compounds into phenols? Benzene comes from #petroleum sources like coal tar and crude oil. 💊 People globally consume over 16,000 metric tons of acetaminophen every year (that’s a lot of aches and pains). Scientists at University of Wisconsin - Madison have developed an alternative, greener way to synthesize this pharmaceutical ingredient using trees, notably poplar #wood. 💊 The alternative process operates continuously, is primarily water-based, and uses environmentaly friendly solvents, potentially making it suitable for industrial scaleup in biorefineries. 💊 Economics compared to established fossil-fuel based acetaminophen production will need further evaluation for the new process, which is available for commercial licensing. #innovation #chemistry #sustainability #climatechange #environment #health

𝐄𝐱𝐩𝐥𝐨𝐫𝐢𝐧𝐠 𝐭𝐡𝐞 𝐏𝐨𝐭𝐞𝐧𝐭𝐢𝐚𝐥 𝐨𝐟 𝐁𝐢𝐨𝐬𝐮𝐫𝐟𝐚𝐜𝐭𝐚𝐧𝐭𝐬: 𝐒𝐮𝐬𝐭𝐚𝐢𝐧𝐚𝐛𝐥𝐞 𝐒𝐨𝐥𝐮𝐭𝐢𝐨𝐧𝐬 𝐟𝐨𝐫 𝐈𝐧𝐝𝐮𝐬𝐭𝐫𝐲 𝐚𝐧𝐝 𝐄𝐧𝐯𝐢𝐫𝐨𝐧𝐦𝐞𝐧𝐭 Biosurfactants are surface-active substances produced by microorganisms, such as bacteria, yeast, and fungi. These compounds have unique properties, including the ability to reduce surface and interfacial tension between individual molecules at the surface and interface. Unlike synthetic surfactants, biosurfactants are biodegradable, less toxic, and often effective at extreme temperatures, pH levels, and salinity. They are categorized into several classes based on their molecular structure, such as glycolipids, lipopeptides, and phospholipids. One of the most studied biosurfactants is rhamnolipid, produced by Pseudomonas aeruginosa, which has applications in bioremediation, enhanced oil recovery, and as an antimicrobial and antifungal agent. 𝐃𝐢𝐬𝐜𝐨𝐯𝐞𝐫 𝐭𝐡𝐞 𝐅𝐮𝐭𝐮𝐫𝐞 𝐨𝐟 𝐆𝐫𝐞𝐞𝐧 𝐂𝐡𝐞𝐦𝐢𝐬𝐭𝐫𝐲 𝐰𝐢𝐭𝐡 𝐁𝐢𝐨𝐬𝐮𝐫𝐟𝐚𝐜𝐭𝐚𝐧𝐭𝐬! 𝐋𝐞𝐚𝐫𝐧 𝐌𝐨𝐫𝐞 𝐚𝐛𝐨𝐮𝐭 𝐓𝐡𝐞𝐢𝐫 𝐒𝐮𝐬𝐭𝐚𝐢𝐧𝐚𝐛𝐥𝐞 𝐁𝐞𝐧𝐞𝐟𝐢𝐭𝐬 𝐓𝐨𝐝𝐚𝐲 @ https://lnkd.in/dgshZ96t The production of biosurfactants has garnered significant interest due to their potential applications in various industries. In environmental management, biosurfactants play a crucial role in the bioremediation of contaminated soils and water, as they can enhance the breakdown of hydrocarbons and heavy metals. In the pharmaceutical and cosmetic industries, they are used for their antimicrobial properties and as emulsifying agents. The food industry benefits from their use as natural preservatives and emulsifiers. Additionally, the agriculture sector employs biosurfactants to enhance soil health and plant growth. The growing awareness and demand for sustainable and eco-friendly products further drive the research and development of biosurfactants, making them a vital component in the shift towards green chemistry and industrial practices. 𝐁𝐢𝐨𝐬𝐮𝐫𝐟𝐚𝐜𝐭𝐚𝐧𝐭𝐬 𝐓𝐨𝐩 𝐂𝐨𝐦𝐩𝐚𝐧𝐢𝐞𝐬: Evonik BASF ecover + method | Europe Jeneil Biotech, Inc. AkzoNobel Lion Givaudan Lavirotte SA Croda Biotensidon s.r.o. Henkel #Biosurfactants #GreenChemistry #SustainableTechnology #EnvironmentalScience #Bioremediation

✳️𝐒𝐨𝐥𝐢𝐝 𝐒𝐭𝐚𝐭𝐞 𝐅𝐞𝐫𝐦𝐞𝐧𝐭𝐚𝐭𝐢𝐨𝐧 (SSF): 🔸Solid-state fermentation (SSF) is a microbial fermentation process that occurs on solid substrates with minimal or no free-flowing liquid. 🔹Microorganisms, including fungi and bacteria, colonize and grow on the surface of solid substrates such as agricultural residues or synthetic materials. 🔸Unlike liquid fermentation, SSF relies on the moisture present in the solid substrate to support microbial growth and metabolism. 🔹SSF is commonly used in various industries, including food, pharmaceuticals, biofuels, and enzyme production. 🔸One of the key advantages of SSF is its ability to utilize inexpensive and abundant agricultural residues as substrates, reducing production costs. 🔹The absence of free-flowing liquid in SSF reduces the risk of contamination, making it a more robust and reliable process. 🔸SSF often leads to higher product yields compared to liquid fermentation, as microorganisms can efficiently utilize the entire surface area of the substrate. 🔹The microbial enzymes and metabolites produced during SSF have diverse applications, including food flavor enhancement, pharmaceutical synthesis, and biofuel production. 🔸The simplicity of SSF setups and the reduced energy requirements make it an attractive option for sustainable bioprocessing. 🔹However, SSF may require longer fermentation times compared to liquid fermentation due to slower diffusion of nutrients in solid substrates. 🔸Monitoring and controlling parameters such as moisture content and temperature are crucial to ensure optimal microbial growth and product formation in SSF. 🔹Advances in bioreactor design and microbial engineering have contributed to the scalability and efficiency of SSF processes. 🔸Overall, SSF offers a promising avenue for the production of valuable bioproducts while utilizing renewable resources and minimizing environmental impact. Image souce: Biotechnology by U.Satyanarayana #biotechnology #biotechnologystudent #biotech #microbiology #science #research #sciencecommunity #lifescience #carrerinbiotech #futureofbiotech #dikshitaramse