Moves to reduce animal testing in Australia and all over the world will change future approaches to clinical research. This global trend will advance the use of non-animal technologies, such as organoids (tissue cultures that replicate organ function). To stay ahead of the curve, NSW Health has created the Non-Animal Technologies Network (NAT-Net), recently announced by the Honourable David Harris MP, Minister for Medical Research. Learn more about NAT-Net and non-animal testing models in NSW: https://lnkd.in/guv-cv8n Image: Anai Gonzalez-Cordero
NSW Medical Research’s Post
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Exploring Progress in Non-Animal Testing 🐶🐭 In the first of a series of interviews, our CEO Dennis Benkmann sat down with Celean Camp, CEO of FRAME Fund for the Replacement of Animals in Medical Experiments, to delve into the transformative strides made in non-animal testing throughout 2023. 🚀 Key highlights include substantial progress in the EU towards phasing out animal testing and the FDA Modernization Act, opening new avenues for utilizing non-animal data. The broader conversation also touched upon the shifting dynamics in the discourse around animal use in research and testing. 🌱 Why does this matter? It goes beyond industry advancements. It's about collectively redefining our approach to research and embracing alternatives that are not just effective but ethical. As part of our commitment, our own brand @ cellQART is at the forefront, developing products aimed at enabling in vitro testing through advanced cell culture applications. Stay tuned for more insights as we continue our interview series with part two next week. #nonanimaltesting #invitro #science #humanandhumane
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Exploring Progress in Non-Animal Testing 🐶🐭 In the first of a series of interviews, our CEO Dennis Benkmann sat down with Celean Camp, CEO of FRAME Fund for the Replacement of Animals in Medical Experiments, to delve into the transformative strides made in non-animal testing throughout 2023. 🚀 Key highlights include substantial progress in the EU towards phasing out animal testing and the FDA Modernization Act, opening new avenues for utilizing non-animal data. The broader conversation also touched upon the shifting dynamics in the discourse around animal use in research and testing. 🌱 Why does this matter? It goes beyond industry advancements. It's about collectively redefining our approach to research and embracing alternatives that are not just effective but ethical. As part of our commitment, our own brand cellQART® is at the forefront, developing products aimed at enabling in vitro testing through advanced cell culture applications. Stay tuned for more insights as we continue our interview series with part two next week. #nonanimaltesting #invitro #science #humanandhumane
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2023 marked a significant milestone for animals used in science, with the passing of legislation to ban cosmetic testing and phase out toxicity testing on animals. While non-animal methods are now being developed and used in these areas, we need to reduce and replace the use of animals in scientific research more generally. In order for this to happen, a system-wide approach to replacement and reduction needs to be applied. Federal funding agencies can lead this charge by promoting the development and use of non-animal methods through setting strategic priorities that shape the future of research. Humane Canada's new Consideration Keystone report delves into this topic and more, seeking to answer the question: What does a humane country look like? Learn more at https://lnkd.in/eW38WAK
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💡 New Insights from #IFER Survey on Funding Challenges for Non-Animal Research 💡 As part of our recent #AnimalMethodsBias survey, we asked IFER researchers about their challenges when seeking funding for non-animal research proposals. The responses reveal significant biases that continue to influence the grant review process. 🔍 Key Findings: • 80% of respondents reported that securing funding for non-animal-based (#NAMS) proposals is harder than animal-based proposals. • 58% of researchers believe the grant review process favors the inclusion of animal experiments. 💬 Researchers shared their perspectives, with many noting that grant reviewers often require proof-of-concept using animal models, even when #NonAnimalModels are available. Medically oriented-funding agencies like the NIH are still heavily invested in animal research to justify clinical relevance. These findings highlight the systemic biases that continue to slow the adoption of #innovative, non-animal research methods. Stay tuned as we continue to explore how these challenges affect the advancement of #ethical, human-relevant science and what steps can be taken to overcome these barriers.
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A new publication by Catharine E. Krebs and Kathrin Herrmann provides a great overview of animal methods bias, a tendency to favor animal-based methods, even when they are unnecessary or when alternative animal-free methods are appropriate. The article examines the evidence and consequences of animal methods bias and discusses efforts to overcome this important issue. Be sure to check it out! #animalmethodsbias #NAMs
🗞️ Hot off the press, a new Coalition to Illuminate and Address Animal Methods Bias publication! "Confronting the bias towards animal experimentation," an introductory overview of animal methods bias for the general public. https://lnkd.in/ettxvX2M New nonanimal research approaches can mimic complex human physiological states and therapeutic responses and are increasingly effective and accessible. They can replace animals in many applications and are becoming a crucial tool for biomedical research and drug development. Acceptance of these new nonanimal methods has been slow and barriers to their broader uptake remain, including: 🐁 Animal methods bias, the preference for animal-based methods where they are not necessary or where animal-free methods are suitable. See our original survey for preliminary evidence: https://lnkd.in/eSFHmKuQ. (Our Evidence Working Group has been hard at work and is excited to present more soon!) Animal methods bias affects the fair assessment of nonanimal studies for publication or proposals for funding, restricting the communication and uptake of these powerful new approaches and standing in the way of improved preclinical predictiveness. Check out the paper for more on the concept of animal methods bias, including an overview of current evidence, how it impacts research assessments, and ongoing efforts to mitigate its harmful effects on human health research! 👇 #animalmethodsbias #scicomm #NAMs #bias
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💡 You want to learn more about #AnimalMethodBias? Read this very important piece and contribution by Catharine E. Krebs and Kathrin Herrmann from the Coalition to Illuminate and Address Animal Methods Bias ⏬
🗞️ Hot off the press, a new Coalition to Illuminate and Address Animal Methods Bias publication! "Confronting the bias towards animal experimentation," an introductory overview of animal methods bias for the general public. https://lnkd.in/ettxvX2M New nonanimal research approaches can mimic complex human physiological states and therapeutic responses and are increasingly effective and accessible. They can replace animals in many applications and are becoming a crucial tool for biomedical research and drug development. Acceptance of these new nonanimal methods has been slow and barriers to their broader uptake remain, including: 🐁 Animal methods bias, the preference for animal-based methods where they are not necessary or where animal-free methods are suitable. See our original survey for preliminary evidence: https://lnkd.in/eSFHmKuQ. (Our Evidence Working Group has been hard at work and is excited to present more soon!) Animal methods bias affects the fair assessment of nonanimal studies for publication or proposals for funding, restricting the communication and uptake of these powerful new approaches and standing in the way of improved preclinical predictiveness. Check out the paper for more on the concept of animal methods bias, including an overview of current evidence, how it impacts research assessments, and ongoing efforts to mitigate its harmful effects on human health research! 👇 #animalmethodsbias #scicomm #NAMs #bias
Confronting the bias towards animal experimentation (animal methods bias)
frontiersin.org
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🗞️ Hot off the press, a new Coalition to Illuminate and Address Animal Methods Bias publication! "Confronting the bias towards animal experimentation," an introductory overview of animal methods bias for the general public. https://lnkd.in/ettxvX2M New nonanimal research approaches can mimic complex human physiological states and therapeutic responses and are increasingly effective and accessible. They can replace animals in many applications and are becoming a crucial tool for biomedical research and drug development. Acceptance of these new nonanimal methods has been slow and barriers to their broader uptake remain, including: 🐁 Animal methods bias, the preference for animal-based methods where they are not necessary or where animal-free methods are suitable. See our original survey for preliminary evidence: https://lnkd.in/eSFHmKuQ. (Our Evidence Working Group has been hard at work and is excited to present more soon!) Animal methods bias affects the fair assessment of nonanimal studies for publication or proposals for funding, restricting the communication and uptake of these powerful new approaches and standing in the way of improved preclinical predictiveness. Check out the paper for more on the concept of animal methods bias, including an overview of current evidence, how it impacts research assessments, and ongoing efforts to mitigate its harmful effects on human health research! 👇 #animalmethodsbias #scicomm #NAMs #bias
Confronting the bias towards animal experimentation (animal methods bias)
frontiersin.org
-
A new publication by Catharine E. Krebs and Kathrin Herrmann provides a great overview of animal methods bias, a tendency to favor animal-based methods, even when they are unnecessary or when alternative animal-free methods are appropriate. The article examines the evidence and consequences of animal methods bias and discusses efforts to overcome this important issue. Be sure to check it out! #animalmethodsbias #NAMs
🗞️ Hot off the press, a new Coalition to Illuminate and Address Animal Methods Bias publication! "Confronting the bias towards animal experimentation," an introductory overview of animal methods bias for the general public. https://lnkd.in/ettxvX2M New nonanimal research approaches can mimic complex human physiological states and therapeutic responses and are increasingly effective and accessible. They can replace animals in many applications and are becoming a crucial tool for biomedical research and drug development. Acceptance of these new nonanimal methods has been slow and barriers to their broader uptake remain, including: 🐁 Animal methods bias, the preference for animal-based methods where they are not necessary or where animal-free methods are suitable. See our original survey for preliminary evidence: https://lnkd.in/eSFHmKuQ. (Our Evidence Working Group has been hard at work and is excited to present more soon!) Animal methods bias affects the fair assessment of nonanimal studies for publication or proposals for funding, restricting the communication and uptake of these powerful new approaches and standing in the way of improved preclinical predictiveness. Check out the paper for more on the concept of animal methods bias, including an overview of current evidence, how it impacts research assessments, and ongoing efforts to mitigate its harmful effects on human health research! 👇 #animalmethodsbias #scicomm #NAMs #bias
Confronting the bias towards animal experimentation (animal methods bias)
frontiersin.org
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#callforreading #recommendations in Methods and Protocols MDPI Title: Harnessing Intronic microRNA Structures to Improve Tolerance and Expression of shRNAs in Animal Cells Authors: Kristie A. Jenkins et al. from Deakin University Read and Download for #free at: https://lnkd.in/gncbP8PJ #methods #protocols #article #rna #cellculture #promoters #animal
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Scientific Director @ Tecniplast | Neuropharmacology PhD | 1st Cialdini Certified Professional in Germany and Italy | Keynote Speaker
🐾 The Continued Importance of Animal Models in Biomedical Research 🧬 Why Animal Models Matter in Today’s Research Landscape 🌍 As outlined in the recent Lab Animal article by Michael C. J. Chang & Franziska B. Grieder (Lab Animal, Vol 53, Nov 2024, 295–297), animal models are indispensable for understanding complex human diseases, despite advancements in alternative methods. Their insights are invaluable, particularly when it comes to human disease mechanisms and developing effective medical treatments. Five Key Benefits of Animal Models in Biomedical Research 📌 1. Translational Insights Animal models provide essential data for translating lab findings into real-world solutions for conditions such as cancer, neurodegenerative diseases, and infectious diseases. 2. Diverse Model Relevance Each animal model, from rodents to nonhuman primates, offers unique physiological insights, ensuring studies remain applicable to human health. 3. Ethical & Regulatory Standards Strong ethical frameworks, like the Animal Welfare Act and Institutional Animal Care and Use Committees (IACUCs), guide the humane treatment of animals, ensuring scientific integrity. 4. Complement to Emerging Technologies While promising, in vitro models like organs-on-chips are still developing. They provide additional insights but work best alongside animal models to deliver a fuller picture of human biology. 5. Preparedness for Health Crises The article underscores the role of animal models in the rapid development of COVID-19 vaccines, highlighting the importance of maintaining robust facilities and trained researchers to handle new health challenges. Building a Future-Ready Infrastructure 🏢 Continued support for animal research infrastructure is critical. With well-equipped labs and comprehensive ethical standards, we can drive innovations that enhance human health, bridging basic research with clinical applications. 🔄 Share this post and follow for more on the essential role of animal models in advancing biomedical science. #AnimalResearch #BiomedicalScience #TranslationalMedicine
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