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In commemoration of Women in Science Day, we shine a spotlight on a recent discovery by Stanford University School of Medicine, which uncovers a significant factor in women's heightened risk for autoimmune diseases. The culprit, Xist, is a long noncoding RNA that exclusively affects females by silencing one X chromosome, thereby initiating complex immune responses not found in males. The longstanding reliance on male cell lines for research has led to a problematic oversight of Xist's role and its implications for women's health. Tragically, the oversight of Xist's crucial role is just the tip of the iceberg. Highlighted by Tjasa Zajc, a mere 4% of biopharma R&D spending is directed towards women's health, underscoring a disconnect that impacts not only health outcomes but also the economic potential. Fierce Pharma's recent podcast reports that addressing this research gap and centering women's health could potentially boost the economy by $1 trillion annually by 2040, signaling an imperative for a shift in medical research and funding towards enhancing women's healthcare. #women #womeninbio #womeninscience #womenshealth

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