mimiX Biotherapeutics’ Post

PhD School projects starting in 2025 #Switzerland 1. Induced quantum dot microscopy of germanium and graphene quantum devices (This position is filled, pleased do not apply anymore) 2. Spin waves get a twist! (project description) 3. Live recording of functional stimuli in single protein molecules using NV-ODMR (project description) 4. Recruiting synthetic metal oxo nanoclusters as enzyme cofactors (project description) 5. Novel mRNA nanotherapeutics against antibiotic-resistant pulmonary infections (project description) 6. Artificial Photosynthesis at Sub-zero Temperatures within Cryo-protective Lipidic Mesophase Nanoconfinement https://lnkd.in/eW2QcBq4

Lillian Gilbreth Post Doctoral Fellowship at Purdue https://lnkd.in/gH674UFH Key Dates for 2024 October 31, 2024: Deadline to receive full application packets with recommendation letters January 2025: the 2025 Lillian Gilbreth postdoc fellows announced; 2025 cohort fellows can start their assignments as early as February 2025 Application Application materials include the following items: Cover letter describing how the Gilbreth Fellowship will help the candidate progress toward their goals in Engineering academia. Curriculum Vitae including list of publications. One-page research statement that includes goals and significance of proposed interdisciplinary work and lists potential Purdue engineering faculty members who can be co-advisors. A one-page essay on the candidate’s proposed broader impact through education/outreach/engagement. Three letters of recommendation that include detailed assessments of (a) the candidate’s qualifications and (b) potential for success in academia through scholarly research and broader impact through research/education/engagement. Apply at Lillian Gilbreth Postdoctoral Fellowships 2025-26 by October 31, 2024. https://lnkd.in/gH674UFH If you have questions about the application process, please email us at coeoaa@purdue.edu.

I'm excited to announce that our latest paper is now available online in Physics in Medicine & Biology! 🎉 🔗 Read it here: https://lnkd.in/eBdQeeeq Key Accomplishments: 1.     Enhanced Understanding of Uncertainties in Ocular Proton Therapy: Our simulations suggest a greater need to control non-systematic uncertainties in ocular proton therapy than previously estimated. 2.     Novel Simulation Model: We've developed a novel simulation model for dose accumulation, which is useful for determining margin requirements in treatment planning. 3.     Introducing OCULARIS: This is the first peer-reviewed publication showcasing the versatility of the open-source OCULARIS treatment planning system—a platform I've developed from scratch as part of my PhD project. #PMB #OCULARPROTONTHERAPY

We are happy to share that VISION affiliate Zsófia Bognár has been awarded a prestigious Postdoctoral Fellowship titled Lipase immobilization for microscopic investigation of enzyme activity (lipaseTEM) through the Marie Sklodowska-Curie Postdoctoral Fellowships (MSCA-PF) 2023. The proposal builds on research carried out by Zsófia Bognár in the Biocatalyst Interactions with Gases (BIG) collaboration involving North Carolina State University and the Technical University of Denmark funded by the Novo Nordisk Foundation: https://biocat.ncsu.edu The project is driven by a shared concern over global water contamination caused by human and industrial activities and the need for a solution to the problem of oily wastewater. We are aiming to develop innovative confocal fluorescent microscopic and transmission electron microscopic methods for the nanoscale imaging of the Thermomyces lanuginosus lipase (TLL), which is known as an effective biocatalyst for lipid removal. Our goal is to gain insights into the structural aspects of enzyme immobilization and identify the attributes that maximize TLL´s biocatalytic reaction rate, which could lead to groundbreaking results and a paradigm shift. By studying lipase-catalyzed chemical reactions, we hope to unlock the gateway of the quantum mechanical world of molecular science. The research will be carried out at laboratories at Novonesis A/S, Topsoe A/S and VISION, DTU Physics. Link to EU Funding & Tenders Portal: https://lnkd.in/dqFKJUWB  #elctronmicroscopy #bioengineering DTU - Technical University of Denmark Novonesis Novo Nordisk Danmarks Grundforskningsfond / The Danish National Research Foundation

Biophysics is a branch of physics that applies physical principles, approaches or methods in studying or understanding a biological problem. [1] Biophysics is a relatively new science that can be attributed to the success of biophysical tools in revealing the molecular structure of deoxyribonucleic acid (DNA).[2] The basis for the study of biophysics began in the 19th century, by a group of physiologists in Berlin, namely Emil du Bois-Reymond, Ernst von Brücke, Hermann von Helmholtz, and Carl Ludwig. Then in 1982, despite the achievements of these four scientists, Karl Pearson introduced the term "Bio-Physics" in his book entitled The Grammar of Science. The book explains the science that connects biology with physics, or what has become known as biophysics.

Welcome to read our peer-review entry 📰 Biophysics and Quantum Limitation of Photoreceptive Processes 🖇 https://lnkd.in/gJZNzuGY 📑 This entry paper is an attempt to explain how the discrete nature of light (energy discreteness in the form of photons) constrains the light detection process all along the evolutionary path, in the not-fully-understood photoreceptive systems of unicellular microorganisms (nonimaging systems) and in the complex and well-known visual system of higher organisms (imaging systems). All these systems are perfect examples of the interplay between physics and biology, i.e., they are the perfect topic of research for biophysicists. The paper describes how photoreceptive and visual systems achieve the goal of photon counting, which information is conveyed by a finite number of photons, and which noise factors limit light-detecting processes. ✍ Laura Barsanti, Paolo Gualtieri #rhodopsin #retina #eye #Euglena #gracilis #noise #information

🧠 Intrigued by Neuromorphic Computing? This computing paradigm mirrors the brain's functionality. Want to delve deeper? Join us for the panel discussion at the International Conference on Neuromorphic Computing and Engineering (ICNCE 2024) at Eurogress Aachen on June 3rd. Titled "Breaking Silos, Crossing Borders, Making Waves: Interdisciplinary Challenges and Opportunities", the discussion aims to engage a wide audience and will be moderated by science journalist Arndt Reuning. Attendance is free. Register by April 15th here: https://lnkd.in/dgATi_J6 Bachelor's and Master's students can apply for complimentary access to the entire conference (limited grants available). For further details, visit the ICNCE 2024 Website. 👉 www.icnce-2024.de/ Markus Diesmann Bastian Leibe Max Lemme Rainer Waser RWTH Aachen University Peter Grünberg Institut (PGI) #JulichSummerAcademy #NeuromorphicComputing #NeuromorphicEngineering #ComputerScience #ArtificialIntelligence #Neuroscience #ComputationalNeuroscience #ElectricalEngineering #InformationTechnology #neuromorphic /mb

Dr Cosmas Mafusire is a senior postdoctoral fellow in the Biophysics Group. He completed his PhD on laser beam propagation through random media in 2012. He is working on using bioinformatics and chem-informatics to study the role of various complex molecules such as CP24, CP26 and CP29 in photosynthetic systems. 'At the heart of photosynthesis is the remarkable efficiency of the energy-capturing phase, coupled with the ability of photosynthetic organisms to dissipate harmful excess energy through specialized mechanisms. Understanding these processes is crucial for designing efficient solar cells that mimic these natural conditions. My research focuses on investigating methods to accurately model natural systems by developing a quantum mechanical understanding of such processes. Central to our efforts is the calculation of an accurate Hamiltonian, as the success of the model hinges on accurately representing the Hamiltonian of natural systems.' This work can be used in the development of solar systems based on mimicking biological systems. #meettheteam #biophysics #research #science #innovation #universityofpretoria

Dr Towan Nöthling is a postdoctoral fellow in the Biophysics Group. He completed his PhD on spectral modelling of photosynthetic light-harvesting complexes at UP. He is currently working on a variety of projects, mainly focusing on spectroscopic modelling, as well as being involved in projects aiming to improve the quality of laser beams and model fungal spore dispersal. Together with Prof. Krüger, Towan recently authored a book chapter about spectral modelling in the book Quantum Mechanics of Biological Systems that is expected to be published by CRC press soon. 'Photosynthesis begins when microscopic complexes composed of proteins and pigments (chlorophylls) absorb light. By using spectroscopy to study *how* these complexes absorb light, we can gain information about the design principles that make photosynthetic light-harvesting so exceptionally efficient. We can then apply those design principles in artificial systems like solar cells and batteries.' Towan enjoys biophysics because it combines the complex beauty of biology and chemistry with the rigour of mathematics and physics. He especially enjoys doing biophysics with other people in the group because 'We get along well, and everybody's personality and sense of humour makes for a fantastic group dynamic.' #meettheteam #biophysics #research #science #innovation #universityofpretoria

🌐 Academic Endeavors in Cryo-EM Research 🌐 Jun-Prof. Dr. Panagiotis Kastritis, the esteemed ERA Chair leading the Hot4Cryo project at NHRF, is poised to contribute significantly through his expertise in cryo-electron microscopy to two noteworthy events in London: 📅 26th February 2024 - Imperial College, London 🎙️ Talk Title: "Visualising Macromolecular Organisation in Native Cell Extracts with High-Resolution Cryo-Electron Microscopy" Dr. Kastritis initiates the week by delivering an insightful lecture at the Department of Life Sciences, Imperial College London. The focus of the talk is centered around the intricate task and scientific goal of his research group, that of deciphering macromolecular organization in complex mixtures, employing state-of-the-art cryo-electron microscopy techniques. 📅 27-28th February 2024 - Wellcome Trust Workshop, London 📚 Workshop Theme: "Understanding Protein Function at Scale: Future Challenges and Opportunities" On the second day of this Wellcome Trust workshop, Dr. Kastritis will oversee discussions as the session chair on “Investigating protein interactions at scale and in situ”. This is a testament to his leadership and expertise, guiding the discourse towards new horizons in understanding the complexities of protein functions. This workshop serves as a unique platform, fostering dialogue among researchers from diverse fields. The collective aim is to delineate key challenges pivotal in advancing our comprehension of protein function at scale. 👏 Congratulations to Dr. Kastritis on this important role, and to all researchers partaking in such events. The synergy of research, collaboration, and leadership in forums like these propels our collective academic pursuit to greater achievements. #CryoEM #ProteinFunction #ResearchAdvancements #ScienceLeadership #Hot4Cryo #ERAChair #NHRF #WellcomeTrust #ImperialCollegeLondon #AcademicResearch