Naima Morys’ Post

Fascinating review about dietary regulation in health and disease. still not sure how "easy" / possible the influence in day-to-day setting are... This review, detailed the nutritional molecular mechanisms that result in improved health. They also propose to decipher factors associated with sex, genetics and age that affect responses to dietary intervention. Altogether, they develop an approach to precision-nutrition medicine to elucidate the health-promoting effects of diet-based therapeutics. Nutritive intervention is viewed as an efficient therapy for counteracting morbidities and maintaining health. It would be interesting to see the influence from nutitive intervention, sport therapy and "convential" therapies... https://lnkd.in/dgkZEuyy

📢 𝙉𝙚𝙬 𝙎𝙩𝙪𝙙𝙮 𝙤𝙣 𝙩𝙝𝙚 𝙇𝙞𝙣𝙠 𝘽𝙚𝙩𝙬𝙚𝙚𝙣 𝙑𝙞𝙩𝙖𝙢𝙞𝙣 𝘾 𝙄𝙣𝙩𝙖𝙠𝙚 𝙖𝙣𝙙 𝙂𝙖𝙨𝙩𝙧𝙞𝙘 𝘾𝙖𝙣𝙘𝙚𝙧 𝙍𝙞𝙨𝙠 📢 A groundbreaking analysis from the 𝙄𝙣𝙩𝙚𝙧𝙖𝙘𝙩𝙞𝙤𝙣 𝙤𝙛 𝙂𝙚𝙣𝙤𝙢𝙞𝙘 𝙖𝙣𝙙 𝘿𝙞𝙚𝙩𝙖𝙧𝙮 𝘼𝙨𝙥𝙚𝙘𝙩𝙨 𝙞𝙣 𝙂𝙖𝙨𝙩𝙧𝙞𝙘 𝘾𝙖𝙣𝙘𝙚𝙧 𝙍𝙞𝙨𝙠: 𝙏𝙝𝙚 𝙂𝙡𝙤𝙗𝙖𝙡 𝙎𝙩𝙤𝙋 𝙋𝙧𝙤𝙟𝙚𝙘𝙩, coordinated by Stefania Boccia Boccia from Università Cattolica del Sacro Cuore, has revealed a significant association between high dietary intake of vitamin C and a reduced risk of gastric cancer, particularly in the non-cardia, intestinal, and diffuse subtypes. What makes this study truly remarkable is that the protective effect of vitamin C remains robust even after adjusting for fruit and vegetable consumption. The optimal intake associated with reduced risk is found to be between 150-200 mg/day. This research, funded by the 𝗜𝘁𝗮𝗹𝗶𝗮𝗻 𝗠𝗶𝗻𝗶𝘀𝘁𝗿𝘆 𝗼𝗳 𝗛𝗲𝗮𝗹𝘁𝗵 (𝗚𝗿𝗮𝗻𝘁 𝗡𝘂𝗺𝗯𝗲𝗿 𝗥𝗙-𝟮𝟬𝟮𝟭-𝟭𝟮𝟯𝟳𝟯𝟵𝟱𝟭) and recently published in 𝘎𝘢𝘴𝘵𝘳𝘪𝘤 𝘊𝘢𝘯𝘤𝘦𝘳 (Impact Factor: 7.4), opens new avenues for prevention strategies in oncology. For the article: https://lnkd.in/dKndt89d #Oncology #GastricCancer #VitaminC #Health #Research #StoPProject

📢 Newly Published Paper Sharing: Nutritional effects on mucosal integrity and immune function 👥 Authors: Lindsey B. Cundra, Manasa Vallabhaneni, Kevin Houston, Michael Saadeh, Alejandra Vargas, Steven M. D'Souza , David A. Johnson 🔑 Keywords: #IBD, #diet, #microbiota, #immunity, intestinal barrier 🎯 " ... Herein this is a review of the peer-reviewed literature pertaining to dietary effects on mucosal integrity, including intraepithelial lymphocyte populations and immune function. This review is intended to explore the underlying mechanisms by which macronutrients impact and modulate the mucosal immune system." 🔗 Read the full article: https://lnkd.in/gjpQ8B6k

GOED is pleased to announce the publication of a review the organization commissioned on the state of omega-3 diagnostics testing. "Omega-3 Polyunsaturated Fatty Acid Status Testing in Humans: A Narrative Review of Commercially Available Options," published in The Journal of Nutrition, highlights the landscape of available omega-3 tests and the importance of diagnostics testing for improving EPA and DHA consumption. Harry Rice, PhD, GOED’s Vice-President of Regulatory & Scientific Affairs noted, “Seeing the overview of scientific evidence on omega-3 levels and health outcomes really gives you a sense of where the strongest evidence exists and where there might be gaps. A review like this will undoubtedly be invaluable during a discussion on dietary reference intakes for EPA/DHA.” Read the full review here: https://lnkd.in/eRTQX8fT

Digesting the complex metabolic effects of diet on the host and microbiome PDF: https://lnkd.in/gt4dzXMB The past 50 years of interdisciplinary research in humans and model organisms has delivered unprecedented insights into the mechanisms through which diet affects energy balance. However, translating these results to prevent and treat obesity and its associated diseases remains challenging. Given the vast scope of this literature, we focus this Review on recent conceptual advances in molecular nutrition targeting the management of energy balance, including emerging dietary and pharmaceutical interventions and their interactions with the human gut microbiome. Notably, multiple current dietary patterns of interest embrace moderate-tohigh fat intake or prioritize the timing of eating over macronutrient intake. Furthermore, the rapid expansion of microbiome research findings has complicated multiple longstanding tenets of nutrition while also providing new opportunities for intervention. Continued progress promises more precise and reliable dietary recommendations that leverage our growing knowledge of the microbiome, the changing landscape of clinical interventions, and our molecular understanding of human biology. DOI - https://lnkd.in/g5rfwGjn

📢 Newly Published Paper Sharing: Nutritional effects on mucosal integrity and immune function 👥 Authors: Lindsey B. Cundra, Manasa Vallabhaneni, Kevin Houston, Michael Saadeh, Alejandra Vargas, Steven M. D'Souza , David A. Johnson 🔑 Keywords: #IBD, #diet, #microbiota, #immunity, intestinal barrier 🎯 " ... Herein this is a review of the peer-reviewed literature pertaining to dietary effects on mucosal integrity, including intraepithelial lymphocyte populations and immune function. This review is intended to explore the underlying mechanisms by which macronutrients impact and modulate the mucosal immune system." 🔗 Read the full article: https://lnkd.in/gHjRgaMu

Consuming too much protein is risky for arteries, and this amino acid is to blame: Study The study, which combined small human trials with experiments in mice and cells in a Petri dish, showed that consuming over 22% of dietary calories from protein can lead to increased activation of immune cells that play a role in atherosclerotic plaque formation, driving the disease risk. Furthermore, the scientists showed that one amino acid - leucine - seems to have a disproportionate role in driving the pathological pathways linked to atherosclerosis, or stiff, hardened arteries. #aminoacid | #atheroscleroticplaqueformation | #immunecells | #pathologicalpathways | #Healthnews Read more:

Atherosclerosis is a leading contributor to heart attacks and strokes, accounting for more than 25% of all-cause mortality. Recent animal studies have suggested that high protein intake may exacerbate this issue by activating a specific signaling pathway in macrophages. A new study published in Nature Portfolio has identified leucine as the key amino acid responsible for this activation and discovered a threshold effect of high protein intake on this pathway. Dietary protein intake greater than about 25g per meal (or about ≥22% of energy requirement) can activate this harmful signaling pathway. These findings offer new insights into the relationship between dietary protein intake and atherosclerosis. Read the full study here: https://lnkd.in/gJKkvt_p

Can spinach thylakoids enhance insulin sensitivity? Research suggests that spinach thylakoids may have the potential to enhance insulin sensitivity. Thylakoids are membrane structures found in chloroplasts, which are responsible for photosynthesis in plants like spinach. These thylakoids contain various bioactive compounds, including proteins, lipids, and pigments, which have been shown to have potential health benefits. Several studies have investigated the effects of spinach thylakoids on insulin sensitivity and glucose metabolism. Some of these studies have shown promising results, suggesting that thylakoids may improve insulin sensitivity by influencing the release of hormones involved in appetite regulation and delaying the digestion and absorption of nutrients in the gastrointestinal tract. For instance, a study published in 2015 in the Journal of Nutritional Science and Vitaminology found that supplementation with spinach thylakoids reduced hunger and improved glucose metabolism in overweight women, indicating potential benefits for insulin sensitivity. While these findings are promising, it's important to note that more research is needed to fully understand the mechanisms involved and to determine the optimal dosage and duration of thylakoid supplementation for enhancing insulin sensitivity. Additionally, individual responses to spinach thylakoids may vary, and it's essential to consult with a healthcare professional before incorporating them into your diet, especially if you have diabetes or other metabolic conditions. #diabetes #insulin #insulinresistance #InsulinSupport #diabetesmanagement #DiabetesSupplements #kiptrack #diets #spinach @highlight Everyone

📃Scientific paper: Dietary intake of vitamin C and gastric cancer: a pooled analysis within the Stomach cancer Pooling (StoP) Project Abstract: Background Previous studies suggest that dietary vitamin C is inversely associated with gastric cancer (GC), but most of them did not consider intake of fruit and vegetables. Thus, we aimed to evaluate this association within the Stomach cancer Pooling (StoP) Project, a consortium of epidemiological studies on GC. Methods Fourteen case–control studies were included in the analysis (5362 cases, 11,497 controls). We estimated odds ratios (ORs) and corresponding 95% confidence intervals (CIs) for the association between dietary intake of vitamin C and GC, adjusted for relevant confounders and for intake of fruit and vegetables. The dose–response relationship was evaluated using mixed-effects logistic models with second-order fractional polynomials. Results Individuals in the highest quartile of dietary vitamin C intake had reduced odds of GC compared with those in the lowest quartile (OR: 0.64; 95% CI: 0.58, 0.72). Additional adjustment for fruit and vegetables intake led to an OR of 0.85 (95% CI: 0.73, 0.98). A significant inverse association was observed for noncardia GC, as well as for both intestinal and diffuse types of the disease. The results of the dose–response analysis showed decreasing ORs of GC up to 150–200 mg/day of vitamin C (OR: 0.54; 95% CI: 0.41, 0.71), whereas ORs for higher intakes were close to 1.0. Conclusions The findings of our pooled study suggest that vitamin C is inversely associated with GC, with a potentially beneficial effect also for int... Continued on ES/IODE ➡️ https://etcse.fr/A2WnG ------- If you find this interesting, feel free to follow, comment and share. We need your help to enhance our visibility, so that our platform continues to serve you.