NewBiologix’s Post

Come check out the future of non-viral Cell and Gene Therapy!

If you are planning on attending #OCTWestCoast next week, be sure to swing by and listen to my fantastic colleague Patty talk about how #realworlddata, #realworldevidence and #AI can already and might in the future help address some of our biggest challenges with long term follow up in #cellandgenetherapy trials. #iconplc #biotech #cellandgenetherapy

I had the pleasure of attending #MTIF 's open day yesterday for a networking event. One of the interesting conversations was around the difference between #invention and #innovation My conclusion is that invention is the spark that creates an idea. Innovation is the monetisation of ideas. Invention is relatively easy and innovation is very hard. Edison understood this when he said "Genius is 1 percent inspiration and 99 percent perspiration". At 3P we spend much of our time helping our MedTech clients innovate, by focusing on how to manufacture their products - "design for commercialisation" is much of our DNA. We also innovate for ourselves and here is another example of one of our successful innovations. We had the idea at a conference several years ago in response to client conversations. It then took a lot of effort and tenacity to understand the market need, develop the technology and then to market and finally to monetise. Teaser alert: Watch our feeds for some really cool innovation we plan to publicise early next year which could be a game changer for cost of goods around #ATMP #cellandgene

🙌 Discover how the collaboration and sharing of expertise between BD and Cell and Gene Therapy Catapult helped to advance #flowcytometry panels to support QC of manufacturing process optimisation in the #PATconsortium. 👉 https://bit.ly/3Rc1XK4 #CAR-T #CellTherapy #GeneTherapy #ATMPs #AdvancedTherapies #TCells

Want to learn how to purify different #genetherapy modalities including pDNA, AAV, LV & exosomes? Sign up for the Chromatography + Filtration Virtual Summit to listen and discuss with experts from the gene therapy community on March 7 https://lnkd.in/ebTytJde #chromatography #filtration #genetherapy #viralvector

🚀 **Insight into Cell and Gene Therapy!** 🚀 Industry leaders discuss the evolving landscape of cell and gene therapy, highlighting the challenges in manufacturing and the necessity of better communication and digital tools. Key takeaways include the importance of adapting traditional processes and leveraging technology to enhance patient outcomes and navigate this multi-stakeholder environment. Stay ahead in personalized medicine by understanding these critical insights and the future of CGT! #CellAndGeneTherapy #PersonalizedMedicine #DigitalTransformation #HealthcareInnovation https://deloi.tt/3SdCd0D

The recording of our recent webinar covering the key findings of the paper 'Leveraging platform and process characterization data to accelerate CGT validation and commercialization’ is now available to view. The webinar explores how an increased number of cell and gene therapies comes with an increase in challenges, including problems such as the restricted availability of materials, a limited product understanding and analytics and a high cost of goods. To address some of these, there is a need to create common approaches to manufacturing novel therapies, which in some cases only differ by their genetic payload.   Watch the webinar on demand here https://bit.ly/4eE7bsk The paper is also available to download here https://bit.ly/3RIcjlh #BioPhorum #AdvancedTherapies #CGT #CellTherapy #GeneTherapy #AdvancedTherapy #CostofGoods #Development #Collaboration

Join us for an informative webcast with industry experts as they address critical challenges in viral vector manufacturing that Resilience's Marlborough, MA site was built to overcome. Situated in one of the fastest-growing life sciences hub and engineered to advance the field of viral vectors and gene therapy, this webinar will introduce the site’s innovative and efficient design. Don’t miss this opportunity to hear from key leaders in the viral vector and gene therapy manufacturing space. Tarran Pierfelice John F. Kerwin Shawn Fitzpatrick Marion Glenn CSPO®, CSM® & Malou Jacinto Key Learning Objectives: Gain insights into the versatile capabilities of the Marlborough Site and Resilience Gene Therapy Network, including multi-product support and flexible manufacturing suites, facilitating seamless transitions from clinical to commercial projects. Explore new technologies and contamination control measures that drive efficiency and quality in viral vector manufacturing. Understand the site’s end-to-end capabilities, spanning from cell bank to drug product fill, and how they streamline the supply chain for greater transparency and productivity.

Technology Spotlight 🧬🔎 Introducing Cellular Highways, developers of the fastest gentle, scalable, sterile cell sorting solution, with potential for huge impact within cell & gene therapy manufacturing. With cost being one of the largest barriers to scaling cell & gene therapy, platforms that enable labs to scale up "efficiently and affordably" are key to progress. We sat down with their CEO Alex Jones (PhD / CEO) to hear about how their technology (Highway1) is doing just this - read more below. 👇 #cellsorting #cellandgenetherapy #lifesciences #technologyspotlight

#FastFacts now available! The evolution of #genetherapymanufacturing Here, Rachel Legmann (Senior Director of Technology, Gene Therapy, Repligen Corporation) explores how integrating process intensification by advanced technologies in both upstream and downstream production of viral vectors impacted yield of potent vectors and #vectorrecovery Read this FastFacts to learn about: ·       How to increase the number of cells producing virus with enhanced specific #viralvector productivity ·       The importance of continuous perfusion to intensified #AAV and #lentivirusproduction ·       Streamlining AAV, plasmid DNA, and #mRNA titer determination using variable pathlength analytical technology Read below: