Retinai’s Post

My how things have changed since 2006 and my role in introducing the first high resolution OCT images with eye tracking. The images shown in this Retinai post are the things we foresaw at the time, and if they can deliver, this is the path to the future potential of retinal imaging and diagnostics. Stay tuned! #retina #ai #ophthalmology #optometry #imaging #retinai

Clario has partnered with PathAI to enhance diagnostic accuracy and efficiency in GI clinical trials. This collaboration offers a single-vendor solution for anatomical pathology services and video endoscopy analysis. The partnership combines Clario's advanced imaging and AI-supported tools with PathAI’s expertise in GI pathology and AI-driven assessments, streamlining trial processes and improving efficiency. The collaboration aims to enhance ulcerative colitis assessments, reduce variability, and accelerate biomarker discovery, unlocking new opportunities for IBD clinical research. Find out more on Pathology News: https://lnkd.in/gu-s5HvV #digitalpathology #pathologynews

Revolutionizing nAMD Diagnosis: Insights from OCT Imaging Biomarkers and AI by RACHEL HANSON, Archana Airody, Sobha Sivaprasad, Richard P Gale 👁️ Key Findings: Identification of 9 key retinal biomarkers relevant to nAMD. AI models can classify a number of these biomarkers, aiding in early detection and treatment. Intraretinal fluid (IRF) is particularly significant in impacting visual outcomes. 🧠 Implications: The integration of AI in ophthalmology signifies a promising advancement in automated analysis of OCT data. This approach enables more precise diagnosis and predictions of disease progression, offering hope for improved patient outcomes in nAMD. https://lnkd.in/dBYBaF2g #Ophthalmology #MacularDegeneration #AIinHealthcare #MedicalResearch #OCTImaging

📮🥳Just received my April/May issue of Eye News in the post 🥳 The digital version is available here: https://lnkd.in/eM-sqts2 Advocates of the old-school can subscribe here for a print copy (free in the United Kingdom and Republic of Ireland): https://lnkd.in/eTWcnpwC Two features from me - one is a brief summary of our Medical Ophthalmology Society UK (MOSUK) 2024 meeting in the Newsround section, and the second is an early 2024 #Oculomics review, gently adducing the fascinating links between the eye and systemic disease: https://lnkd.in/eNKa5e28 Advancements in technology like imaging, AI, and #bigdata are enabling the detection of previously undiscovered connections and risk factors at earlier stages, and fascinating links are being unveiled. For example, associations between childhood lazy eye and increased risk of hypertension, obesity, and heart attacks in adulthood, as well as links between retinal thickness and gum disease, and the potential for screening rare conditions like #moyamoya disease through retinal imaging. This year, The Royal College of Ophthalmologists (RCOphth) annual congress is including a session on "Oculomics: re-linking the eye and the body" to explore this rapidly evolving field. As more biomarkers are discovered, there is a potential to revolutionize predictive, preventive, and #personalizedmedicine by enabling earlier intervention and tailored treatment strategies. Not only that, but we can develop low-cost screening methods to improve access to preventive care globally. Looking ahead to 2024 and beyond, the focus is on expanding #biomarkers beyond imaging modalities to include molecular and histologic characteristics, offering promise for early detection of diseases like Alzheimer's. The UK Biobank and other global biomedical databases are feeding this research and it is an exciting time. Watch this space. If you are an expert and want to contribute your insights, please feel free to connect (details at the bottom of this article: https://lnkd.in/eNKa5e28)

I'm ecstatic to share that our paper, "Comparing clinical and echocardiographic outcomes following valve-sparing versus transannular patch repair of tetralogy of Fallot: a systematic review and meta-analysis," has recently been published in the Oxford Academic journal "Interdisciplinary Cardiovascular and Thoracic Surgery" (ICVTS). This publication, which I have had the honour of being co-first author on, marks the culmination of a mammoth two-year effort. Our study confirms the well-established increased risk of pulmonary insufficiency following TAP repair while also demonstrating that VS repairs are associated with several improved clinical outcomes. Continued research can identify the criteria for adopting a VS approach as opposed to a traditional TAP repair. Extremely grateful to my mentors, Mahim Malik and Russell Seth Martins, and colleagues for helping this study come to fruition. Check out the full paper here: https://lnkd.in/dM7ghTPB

Spreading Awareness on Extensive Macular Atrophy with Pseudodrusen-like Appearance (EMAP)! EMAP is a severe retinopathy that progressively leads to legal blindness approximately four years after diagnosis. Patients frequently seek medical advice at an age compatible with that of Age-related Macular Degeneration (AMD), underscoring the necessity of an accurate differential diagnosis. Thanks to my colleague Lorenzo Bianco for co-authoring this manuscript with me, and to Prof. Isabelle audo for giving us the opportunity to take a look at the elder EMAP cohort followed at the Quinze-Vingts Hospital. Now accessible in Ophthalmology: https://lnkd.in/d9pBjUTR

The Global Interventional Radiology Imaging Market is projected to grow from $25.5 billion in 2024 to $40.0 billion by 2030, registering a #CAGR of 7%. This rapid expansion is fueled by increasing cases of chronic diseases such as #cancer and #cardiovascular conditions, which require precise imaging for accurate diagnosis and treatment. 🔍 Key Market Drivers: Prevalence of #Chronic #Diseases: Rising cases of cancer, cardiovascular diseases, and other chronic conditions are pushing the need for advanced imaging. Technological Advancements: Innovations like high-resolution fluoroscopy, #CTscanners, and #MRI systems are revolutionizing interventional procedures. Minimally Invasive Procedures: The global shift towards minimally invasive interventions is driving demand for sophisticated imaging solutions. 💡 Major Applications: #Cardiology: Imaging plays a crucial role in diagnosing and treating heart conditions. #Oncology: Vital for cancer treatment planning and real-time intervention. #Urology & #Nephrology: Precise imaging aids in kidney and urinary tract interventions. 🚀 Future Outlook: The future of interventional radiology is promising with further AI integration for real-time image analysis and enhanced personalized medicine. Emerging markets in Asia-Pacific and Latin America are set to experience robust growth due to increased healthcare infrastructure investments. 🏢 Top Competitors: Siemens Healthineers GE HealthCare Philips Canon Medical Systems Corporation Hitachi High-Tech Analytical Science Samsung Medison SHIMADZU CORPORATION 🌍 Regional Insights: #NorthAmerica dominates due to advanced healthcare systems and rapid adoption of new technologies. #Europe is growing due to the rise in chronic diseases and regulatory support. #AsiaPacific is the fastest-growing region, driven by healthcare infrastructure expansion and government initiatives. The global interventional radiology imaging market is on a transformative journey, driven by technological innovations and increasing demand for less invasive, highly precise medical procedures. Stay ahead by investing in this rapidly growing sector! Get your FREE SAMPLE REPORT here; https://lnkd.in/d4JUCRp5 #InterventionalRadiology #HealthcareInnovation #MedicalImaging #MarketTrends #HealthcareTechnology #BusinessIntelligence #MarketStudyReport #MarketResearch #Consulting #BusinessReport #MarketInsights #Industrytrends

Ophthopedia Update:LONGITUDINAL ANALYSIS OF MICROVASCULAR CHANGES IN SICKLE CELL DISEASE USING SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY: Purpose: To analyze the changes in macular vascular densities (VDs) and foveal avascular zone (FAZ) over a 6-year period using swept-source optical coherence tomography angiography in patients with sickle cell disease compared with unaffected control subjects. Methods: Thirty eyes of patients with sickle cell disease and 12 eyes of unaffected control subjects matched for age and ethnicity were examined at a 6-year interval using the same imaging protocol, including ultra-wide-field angiography, swept-source OCT, and 3 × 3-mm optical coherence tomography angiography. The macular VD and FAZ were measured on ImageJ software according to previously reported algorithms. Results: In sickle cell eyes, the mean FAZ significantly increased (P < 0.01), and the VD decreased in the foveal (within a circle of 1.5 mm in diameter around the foveal center) and temporal areas in both the superficial and the deep capillary plexuses (P < 0.01). The VD did not change over time in the parafoveal area (annulus between two circles of 1.5 and 3 mm in diameter) and in the superior, inferior, and nasal sectors. No worsening of peripheral retinopathy was observed in the cohort during the follow-up, except for one eye that developed sea-fan. In the control eyes, no microvascular change was observed over time in FAZ size and VD. Conclusion: These longitudinal optical coherence tomography angiography findings in patients with sickle cell disease showed an enlargement of the FAZ and a decrease in VD in the temporal and perifoveal regions despite the absence of progression of peripheral retinopathy, suggesting a worsening of the macular nonperfusion over time in sickle cell disease. #Ophthotwitter #Ophthalmology #Retina

In the field of cardiovacular diseases, quantitative PET and SPECT may enhance possibilities for screening, early diagnosis, therapy prediction, guiding treatment and assessing likelihood of disease recurrence. Are you curious about the recent technical advances that allow for quantitative molecular cardiovascular imaging, its applications, and the challenges that need to be overcome to achieve clinical implementation? Read about it in our recently published open-source paper: 'The clinical value of quantitative cardivoascular molecular imaging: a step towards precision medicine' in the British Journal of Radiology. https://lnkd.in/e_jNZGjy Gijs van Praagh, Pieter Nienhuis, Alwin T., Nick van Rijsewijk, Dik ten Hove, Nouf Mushari, Tonantzin Samara Martínez-Lucio, Oscar Isaac Mendoza-Ibañez, Joyce van Sluis, Charalampos Tsoumpas, Andor Glaudemans, Riemer Slart