The Alliance applauds the work of The Paul G. Allen Frontiers Group Discovery Center for Human Brain Evolution and the lab of Chris Walsh of Boston Children's Hospital who have found that a third or more of the fastest-evolving regions of the human genome (known as human accelerated regions or HARs) are active during brain development and that mutations in HARs contribute to autism among families with shared ancestry. Read more about it below
The lab of Chris Walsh of Boston Children’s and the The Paul G. Allen Frontiers Group Discovery Center for Human Brain Evolution, has found that a third or more of the fastest-evolving regions of the human genome (known as human accelerated regions or HARs) are active during brain development, and that mutations in HARs contribute to autism among families with shared ancestry. Walsh, Ryan Doan, Ph.D., DABMGG, FACMG Taehwan Shin, Janet Song and other colleagues now extend the HARS–autism link in a larger cohort of smaller families with more diverse ancestry, mainly from the U.S. They also find that mutations in non-coding regions of the genome contribute to autism risk as well. 👇
