SOBHANJAN BHUNIA’s Post

DOTA PEG https://lnkd.in/gj4QuzGX DOTA PEG linkers are an important class of molecules widely used in pharmaceutical research and development. These linkers are composed of a DOTA chelator and a polyethylene glycol (PEG) chain. The DOTA moiety is used to bind to metal ions such as copper, gallium or lutetium, while the PEG chain provides stability and solubility to the resulting conjugate.

Successfully published review artical on Toxicity of Sodium Lauryl Sulphate and Therir good substitutents in Word journal of pharmaceutical research having impact factor of 8.084.

Taming 3-Oxetanyllithium using continuous flow technology in late-stage pharmaceutical analogue synthesis As a useful bioisostere for dimethyl and carbonyl groups for the improvement of physiochemical properties of drug candidates, oxetane ring continues to make its presence felt. https://lnkd.in/gHgmMyv7

I'm happy to share my first review article titled as "Liraglutide innovations: a comprehensive review of patents (2014–2024)" in the journal of Pharmaceutical Patent Analyst, Taylor and Francis. Special thanks to my supervisor Prof.Amit Kumar Goyal. In this article I've mentioned all the patents published related to Glucagon-like peptide-1 agonist "liraglutide". Read the full article here: https://lnkd.in/dXppUsUx

I am happy to inform my paper has been accepted in fluid phase equilibria "UNIFAC and Wilson Models to Correlate Solubility of Pharmaceutical Compounds in Supercritical Carbon Dioxide" https://lnkd.in/ggPTYuQZ

A recent article, published in Pharmaceutical Research, highlighted the problems associated with visible and sub-visible particle formation in protein formulations due to hydrolytic degradation of polysorbate 20. Learn more https://ow.ly/AG2h30szgy9 Find out what we have been doing to help reduce the risk of visible and sub-visible particle formation. Read more here ow.ly/GVPP30synBE

The X-Pulse Broadband Benchtop NMR Spectrometer can easily differentiate between paracetamol and its regioisomers, thanks to its ability to readily detect regioisomerisation, which frequently occurs in pharmaceutical compounds. Want to find out more? Download the application note: https://okt.to/A7bDKm #NMR #NMRSpectroscopy #Pharma #PharmaIndustry #Spectroscopy

New review paper published in European Journal of Pharmaceutical Sciences: 𝗟𝗮𝗽𝗼𝗻𝗶𝘁𝗲 𝗻𝗮𝗻𝗼𝗰𝗹𝗮𝘆𝘀 𝗳𝗼𝗿 𝘁𝗵𝗲 𝘀𝘂𝘀𝘁𝗮𝗶𝗻𝗲𝗱 𝗱𝗲𝗹𝗶𝘃𝗲𝗿𝘆 𝗼𝗳 𝘁𝗵𝗲𝗿𝗮𝗽𝗲𝘂𝘁𝗶𝗰 𝗽𝗿𝗼𝘁𝗲𝗶𝗻𝘀 Laponite, a synthetic nanoclay used alone or combined with various polymers, shows promise for sustained delivery of therapeutic proteins. However, controlling Laponite-protein interactions is challenging due to complex and poorly understood factors. This review aims to clarify these issues by discussing the factors that influence protein loading and release. Thanks a lot to all the people involved: Ainhoa Gonzalez Pujana, Manoli Igartua Olaechea and Rosa Maria Hernandez. Link: https://lnkd.in/d8AVcDFf

𝗕𝗼𝗿𝗼𝗻-𝗖𝗼𝗻𝘁𝗮𝗶𝗻𝗶𝗻𝗴 𝗕𝘂𝗶𝗹𝗱𝗶𝗻𝗴 𝗕𝗹𝗼𝗰𝗸𝘀 𝗳𝗼𝗿 𝗠𝗲𝗱𝗶𝗰𝗶𝗻𝗮𝗹 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵: 𝗕𝗲𝗻𝘇𝗼𝘅𝗮𝗯𝗼𝗿𝗼𝗹𝗲𝘀 Boronic acids are recognized as useful scaffolds for pharmaceutical compounds, due to their unique property to form a reversible covalent bond at the boron center with various nucleophilic functional groups. TCI can offer a wide range of benzoxaboroles with various functional groups on each benzene ring useful for further derivatizations and we also can provide custom synthesis of derivatives including bulk synthesis. 𝗟𝗲𝗮𝗿𝗻 𝗠𝗼𝗿𝗲: https://lnkd.in/gSfn7tGK #bulksynthesis #customsynthesis #pharmaceuticalcompounds #benzoxaboroles #medicinalresearch #boronicacids #researchchemicals #reagents

Article No. 127 Title: Synthesis, Molecular Docking, Molecular Dynamic Simulation Studies, and Antitubercular Activity Evaluation of Substituted Benzimidazole Derivatives Journal:  Advances in pharmacological and pharmaceutical sciences Impact Factor: 2.1 DOI: https://lnkd.in/gB383NHN