US Pharmacopeia’s Post

Ever imagined a situation where access to your go-to #Painkiller was at risk? Imagine dealing with a muscle sprain after a weekend of physical activity but without your muscle relaxant or painkiller of choice. On another level imagine a situation where your loved one is hospitalized but can't get better because they are suffering from an infection caused by a resistant agent (bacteria). You are out of options with the risk of them succumbing to the disease. All these point to #Sustainability in #Pharmacy and #PharmaceuticalSciences. Key being to conduct research in a way that guarantees reliable access to novel therapies without depleting natural reserves while also not risking access to care for future generations either through irrational use of resources including medicines and managing healthcare waste in a responsible way. Reading this interview by the International Pharmaceutical Federation (FIP) with Mia Sivén on #SustainablePharmacy sparked my interest in the principle of #CircularPharmacy especially in line with the ongoing discussions on #ExtendedProducerResponsibility in #Kenya. How do we ensure we have a circular ecosystem where health products don't get disposed without care while at the same time ensuring communities play an active role in safeguarding their health. Read: https://lnkd.in/dX5e8Tu3 African Pharmaceutical Network (APN) Pharmaceutical Society of Kenya Pharmaceutical Society of Uganda Pharmaceutical Society of Zimbabwe (PSZ) Kenya Association of Pharmaceutical Industry (KAPI)

🏥 😷Lack of access to healthcare, particularly medicines, has led to the rise of opportunists seeking to fill the gaps, resulting in deadly consequences in some cases. Research indicates that one-fifth of medicines in Africa may be substandard or fake, leading to as many as 500,000 deaths a year in sub-Saharan Africa. 💊💉“Substandard medicines" are authorized drugs that do not meet quality standards or specifications, while "falsified medicines" are intentionally misrepresented in terms of their identity, composition, or source. 💀💲In Africa, antibiotics and antimalarial products are among the most frequently falsified medicines, contributing to ineffective treatments and the survival of resistant strains. The World Health Organization estimates that caring for people who have used falsified or substandard medical products for malaria treatment in sub-Saharan Africa costs between $12 million to $44.7 million yearly. 🌍 The African Union, governments, pharmaceutical companies, and patients all have a role to play in strengthening supply chains and improving access to safe, affordable medicine across the continent. This can be achieved by; 1️⃣ introducing or revising legislation to prevent medicine-related offenses. ⚖️👮🏿♂️ 2️⃣ enhancing infrastructure and logistics. ⚙️ 3️⃣ implementing better surveillance and monitoring systems. 🔍 4️⃣ reporting any cases of substandard or falsified medical products to national health authorities. 📝 #medicines #Africa #globalhealth #africanunion #pharmaceuticals #antibiotics #antimalarial #substandardmedicines #falsifiedmedicines #pharmacy

First case of the clade 1b mpox detected in Germany. This is the second case of this variant to be recorded in Europe after a severe outbreak in Africa (DRC) earlier this year. Clade 1b tends to cause a higher number of severe infections, is more transmissible (including through routine close contacts), and displays a higher mortality rate than clade 2 mpox. The German case appears to be acquired abroad. To date, only a handful of cases have been reported for clade 1b outside Africa. In addition to Germany, cases have been reported in Sweden,  Thailand, Pakistan, and the Philippines. Link: https://sco.lt/6E9nHc #monkeypox #mpox #Africa #gemany #health #globalhealth #publichealth #outbreak #medicine #biotechnology #pharmaceuticals #infectiousdiseases #WHO #CDC #FDA #ECDC

🌟This is an great opportunity to accomplish my knowledge regarding GMP, ICH guidelines and historical disaster certified on IPI Academy on 9 th July 2024. 👉1962 - Thalidomide tragedy more than 10 k childrens Born with severe deformities 👉1972 - Contaminated 5 % dextrose ,5 patient died after administration 👉1982 - Tylenol Causing Acetaminophen poisoning seven unexpected peoples were died. 👉1993 - The barr ruling 👉2001 - Baxter Althane disaster with 53 sudden death 👉2004 - vioxx ( rofecoxib) causes increase in heart attack 👉2008 - heparin scandle causes 82 confirmed deaths. 👉2009 - Mypikin An teething mixture causes kidney failure in nigeria and 84 Childers were died. 👉2015 - Sanofi Epilepsy drug valproate attacks over 4000 childrens with deformities. 👉2017 - Peter S. had manipulated at least 14,000 drugs, the quality of which was "not insignificantly" diminished. The offenses took place in in nearby nearby Bottrop between 2012 and 2016. 👉2018 - Valsartan Contaminated with NDMA The U.S. Food and Drug Administration (FDA) stated in a press release on July 13, 2018. 👉2023 - Cough syrups made in India and Indonesia have been linked to the deaths of more than 300 children.

World Anticounterfeit Day counterfeit or illegal drugs has been one of the major public health crises in the world especially in Africa there is a rise of counterfeit pharmaceutical sales and the black market is about 8Billion USD killing tens of thousands Africans annually. most of these medications are found along the road, we think roadside medication vendors are doing good but it is causing more harm than good. one of the major ways of stoping this bad practices is to improve pharmaceutical practices , easy access to licensed pharmacies, proper control of pharmaceutical products, strengthen border checks by involving safe Technology innovation into the pharmaceutical space. especially AI it has the potential of breaking the counterfeit chain and reducing the drug black market . at EKOSE Holdings SARL this is our major concern, we envision an Africa where no person dies from counterfeit or expired products . join us on this journey. #worldanticounterfeitday #fightthefakes #africapharmaceuticalcouncil World Health Organization Prof. Ashley George Pan African Health Systems Network Africa CDC Centers for Disease Control and Prevention eliane doumbe Darryl Lerouge AMBU LOIUS NGANG Olivier Ngwe Jean-Patrick KETCHA

📢 Upcoming Industry Discussion Forum For ALL interested African National Medicines Regulatory Authorities #NMRAs Topic: Understanding Swissmedic MAGHP and its Role in Health Product Security in Africa. World Health Organization (WHO) has estimated that nearly two (2) billion people in the world have no access to essential medicines. Factors affecting access to medicines are enormous and vary from one country to another. Within the African context, prevalent factors affecting access to medicines include; high disease burden, limited local manufacturing, weak supply chain systems, weak regulatory systems, circulation of fake and counterfeit medical products just to mention a few. With regard to regulation and approval of medical products in ensuring availability of essential therapeutics, it is imperative for national medicines regulatory authorities to take advantage of existing interventions such as the Swissmedic Marketing Authorisation for Global Health Product (MAGHP) to ensure timely access of essential therapeutics especially in low - and middle- income countries in sub-Saharan Africa. The MAGHP aims at accelerating access for therapeutic products targeting a concrete medical need in endemic regions. In the wake of Africa taking advantage of existing interventions to address regulatory challenges hindering timely access to essential medicines, mortality rate will reduce and the quality of health in the continent will increase. Join us for this industry discussion forum as we shed light on what the Swissmedic MAGHP is, how African NRA's can benefit from using it and why NRA's should consider adopting this intervention for their drug regulation and approvals. Register: https://rb.gy/iy9kcb 🗓 Date: July 19, 2024 ⏲ Time: 2PM EAT #RegulatorySystemsStrengthening #AccessToMedicines

Medicines save lives and improve #health, but their high costs significantly impact #access to health care. In most low- and middle-income countries (LMICs), individuals and households often face direct out-of-pocket payments to obtain necessary medications. Therefore, financing the #pharmaceutical sector is essential for achieving #universal access to health care. APIFA is committed to engaging partners and devising #strategies to enhance pharmaceutical-sector financing, mobilizing stakeholders, and building coalitions, including the private sector to improve access to medicines by strengthening #local production capacities. In Nigeria, APIFA continues to collaborate with Emzor Pharmaceutical and the European Investment Bank (EIB) to expedite the fight against malaria in Africa by supporting the first antimalarial Active Pharmaceutical Ingredients (APIs) #manufacturing plant by the former even as we support more #manufacturers to move upstream On the sidelines of the World Health Organization Global event discussing financing with IFC - International Finance Corporation, African Development Bank Group, Unitaid, African Export-Import Bank (Afreximbank), IQVIA, local manufacturers, and other stakeholders. #APIForAfrica

Unmasking the Deadly Counterfeit Drug Crisis in Africa 🌍 The scale of this issue is staggering and has dire implications for public health and safety. 💀500,000 Deaths Annually: Counterfeit drugs are responsible for an estimated 500,000 deaths every year in sub-Saharan Africa. This alarming figure highlights the deadly impact of fake pharmaceuticals on communities. 📈70% of Drugs in Nigeria: In some areas of Nigeria, it is reported that as much as 70% of the drugs in circulation could be counterfeit. These drugs often lack the necessary active ingredients, leading to treatment failures and drug resistance. 📊42% of Fake Drugs Globally: Between 2013 and 2017, Africa accounted for 42% of all fake drugs reported to the World Health Organization (WHO), underscoring the continent’s vulnerability to this crisis. 💸$200 Billion Global Market: The global counterfeit drug market is valued at over $200 billion, with Africa being one of the hardest-hit regions. 🦟40% of Malaria Drugs: Approximately 40% of the malaria drugs sold in Nigeria are fake, contributing significantly to the mortality and morbidity rates associated with this preventable and treatable disease. The proliferation of fake pharmaceuticals undermines trust in healthcare systems, exacerbates health inequalities, and places millions of lives at risk. At ForgeStop, we are dedicated to combating this crisis by deploying cutting-edge consumer authentication technology. Our goal is to empower consumers to easily verify the authenticity of their medications, ensuring that they have access to safe and effective treatments. We believe that through innovation and collaboration, we can protect lives and build a more secure future for healthcare in Africa and beyond. 💻 www.forgestop.com 📧 hello@forgestop.com #CounterfeitDrugs #PublicHealthCrisis #Africa #Nigeria #ForgeStop #HealthcareInnovation #ConsumerSafety

Vivian Nwakah is making a powerful impact in Africa's healthcare industry by tackling the rampant issue of counterfeit drugs. Through her digital platform, Medsaf, founded in 2016, she has created a reliable solution for hospitals and pharmacies in Nigeria to source safe, vetted medications. Medsaf ensures that quality drugs reach healthcare providers, reducing the risk of substandard products and ultimately saving lives. With over 3 million orders financed and 4000+ facilities onboarded, she is transforming the medical supply chain across the continent, starting from Nigeria. Counterfeit drugs pose a significant threat to healthcare in Africa, with the WHO reporting that 42% of such cases are from the African region. Nwakah's leadership in Medsaf is essential to fixing this fragmented supply chain. Her efforts boost confidence in Africa's healthcare system and bring life-saving medications to underserved areas. Her dedication to transparency and safety revolutionises healthcare, one safe medicine at a time. Read up: https://lnkd.in/dQ2M3ADB #HealthcareInnovation #Medsaf #CounterfeitDrugs #AfricaRising #PharmaTech #NigeriaHealth #HealthTech

The #availability of #essentialmedicines with guaranteed #quality plays a crucial role in the #advancement of global health #goals, such as eliminating #preventable deaths of new-borns and children under five, combating waterborne and other #communicablediseases, ending the #epidemics of AIDS, tuberculosis, malaria, and neglected tropical diseases, and achieving universal health coverage (#UHC). There are frequently gaps or #shortages in the #globalsupply of certain essential medicines because there are #few or no #GMP-compliant manufacturers producing it. Encouraging pharmaceutical producers to meet #global quality #standards, like World Health Organization prequalification (#WHOPQ), can assist in resolving concerns about the availability of quality-assured essential medicines.   Through The World Bank-funded #IMPACT project, Bloom Public Health, in #partnership with #NIPRD, worked to #strengthen the capacities and capabilities of local pharmaceutical manufacturers in #Nigeria to produce quality-assured medicines and address critical shortages or gaps in the supply of essential medicines.   In the past ten months, Bloom Public Health, in this landmark pharmaceutical intervention, has been providing #technicalassistance to #five selected local #pharmaceuticalmanufacturers in #Nigeria towards the attainment of #WHOPQ of their #antimalarials and further bioavailability/bioequivalence studies support for one of the pharmaceutical manufacturers.   This #intervention is sure to address issues of #medicinesecurity, and poor-quality essential medicines, while providing local pharmaceutical manufacturers with vast #opportunities to #access the global medicine market, making them #eligible for donor-sponsored tenders for medicines.   Bloom Public Health is taking significant #steps towards #transforming the pharmaceutical manufacturing sector in #Nigeria through diverse interventions, and we will not rest on our oars until we achieve our #goal. 📹:Snippets of the #IMPACT project's capacity-building workshop #TheWorldBank #IMPACTproject #pharmaceuticalmanufacturers #WHOPQ #capacitybuilding #GMP #Standards #qualitymedicines #antimalarials #NIPRD #BloomPublicHealth #Nigeria #Cameroon #Rwanda #Botswana #Zambia