Every year, the last day of February marks rare disease day. Across the globe, over 6000 different rare diseases have been identified, impacting approximately 300 million individuals. With a deepening understanding of the biology of rare diseases and the rapid advancement of novel therapies, an increasing number of enterprises and institutions are contributing to research and development in this field. WuXi Biology offers integrated services for rare disease drug research, from the generation and characterization of animal models to colony management and pre-clinical pharmacology research. Our platform encompasses numerous rare diseases, including hematologic, metabolic, immunologic, and neurologic diseases. #RareDiseases #RareDiseaseDay #RareDiseaseDay2024 #Biotech #DrugDiscovery #DrugDevelopment
WuXi Discovery Services’ Post
More Relevant Posts
-
Degenerative retinal diseases, characterised by photoreceptor loss are a significant cause of global visual impairment. However, there are few treatment options available for these diseases. We are excited to share a recent study using our TRC research chemicals to identify a therapeutic small molecule via phenotypic screening. The study demonstrates efficacy in preclinical disease models, providing promising proof-of-concept results. Learn more about the study published in the International Journal of Molecular Science: https://okt.to/RJP9gj #ProductCitation #ResearchChemicals #ScienceforaSaferWorld
To view or add a comment, sign in
-
🔬 Exciting Update in the World of Healthcare! Join me at [Advances in Molecular Diagnostics & Precision Medicine] for a deep dive into Molecular Diagnostics and Precision Medicine. 🌐 📅 Date: [August 12–13] 📍 Location: [Rome, Italy] 🚀 Explore groundbreaking advancements, connect with industry leaders, and stay at the forefront of healthcare innovation. Don't miss out on the future of personalized medicine! 🔗Website: https://lnkd.in/gUXStGxE Molecular Diagnostics & Precision Medicine See you there! #rome #italy #event #molecularbiology #moleculardiagnostics #proteomics #dna #rna #rnatherapeutics #mutations #microfluidics #genetictesting #genomics #genomicmedicine #pcr #pharmacogenetics #protein #genetics #precisionmedicine #pharmacogenomics #artificialintelligence #clinicaltrials #researchers #therapeutics #pathology #biomedical #bioinformatics #massspectrometry #nutrigenomics #pcr #mutation #pathogens #biomedicalresearch #digitalpathology #sciinovgroup #MDPM2024
To view or add a comment, sign in
-
🔬 Exciting Update in the World of Healthcare! Join me at [Advances in Molecular Diagnostics & Precision Medicine] for a deep dive into Molecular Diagnostics and Precision Medicine. 🌐 📅 Date: [August 12–13] 📍 Location: [Rome, Italy] 🚀 Explore groundbreaking advancements, connect with industry leaders, and stay at the forefront of healthcare innovation. Don't miss out on the future of personalized medicine! 🔗Website: https://lnkd.in/gUXStGxE Molecular Diagnostics & Precision Medicine See you there! #rome #italy #event #molecularbiology #moleculardiagnostics #proteomics #dna #rna #rnatherapeutics #mutations #microfluidics #genetictesting #genomics #genomicmedicine #pcr #pharmacogenetics #protein #genetics #precisionmedicine #pharmacogenomics #artificialintelligence #clinicaltrials #researchers #therapeutics #pathology #biomedical #bioinformatics #massspectrometry #nutrigenomics #pcr #mutation #pathogens #biomedicalresearch #digitalpathology #sciinovgroup #MDPM2024
To view or add a comment, sign in
-
Business Development Executive at i3 Global Research | Healthcare | Biotechnology | Pharma | Oncology
A Complete Guide to “𝐄𝐩𝐢𝐠𝐞𝐧𝐞𝐭𝐢𝐜𝐬” [PDF-Guide] ➤ 𝐂𝐥𝐢𝐜𝐤 𝐡𝐞𝐫𝐞 𝐭𝐨 𝐆𝐞𝐭 𝐏𝐃𝐅: https://lnkd.in/d9nXAGMV #Epigenetics is a mechanism that includes #phenotypic alteration without permanent genotypic change, which occurs through chromatin modification, #DNAmethylation, histone modification, chromatin-regulating proteins, and non-coding #RNAs. These modifications play a significant role in developing and progressing several #oncological and non-oncological diseases. Thus, epigenetic changes are of value in #diagnostic and prognostic terms. The rising incidence of #chronicdiseases due to growth in the global aging population supports the growth of this market. As per United Nations data, the percentage of the population aged 65 years or over is increasing globally. In 2022, about 9.7% of the global population was aged 65 years or over. This number is expected to increase to 11.7% in 2030 and 16.4% in 2050. People from the older population have reduced #immunity and weakened body systems, making them susceptible to chronic diseases, including #cardiovasculardisease (CVD), neurological disorders, #cancer, and metabolic disorders, among others. ➤ 𝐄𝐧𝐝-𝐔𝐬𝐞 𝐈𝐧𝐝𝐮𝐬𝐭𝐫𝐲 : 1 Pharmaceutical & #Biotechnology Companies 2 Academic & #Research Institutes 3 #Hospitals & Diagnostic Laboratories ➤ 𝑮𝒆𝒕 𝑵𝒆𝒘𝒔: https://lnkd.in/dwSZxpQg ➤ 𝑲𝒆𝒚 𝑷𝒍𝒂𝒚𝒆𝒓𝒔: Thermo Fisher Scientific Inc. (U.S.), Merck KGaA (Germany), Illumina, Inc. (U.S.), QIAGEN N.V. (Netherlands), New England Biolabs (U.S.), Epigentek Group Inc. (U.S.) #Epigenomics #GenomicMedicine #DNAmethylation #HistoneModification #EpigeneticTherapies #PrecisionMedicine #EpigeneticResearch #GenomicAnalysis #MolecularBiology #EpigeneticDiagnostics #HealthTech #MedicalResearch #BiotechIndustry #GenomicTesting #Biomarkers #InnovationInHealthcare
To view or add a comment, sign in
-
🎉 Happy #WorldRNADay! Today, we celebrate the world of #RNA, a crucial molecule that plays a key role in encoding, regulating, and expressing our genes. While DNA serves as the instruction manual, RNA takes on the essential job of carrying out those instructions within our cells, helping to build the proteins that keep our bodies functioning On this special day, we’re excited to highlight a groundbreaking advancement in biomedicine using RNA to tackle chronic liver diseases 🌟Dr. Mariluz Martinez-Chantar and her team at the “Liver Disease” lab #CICbioGUNE BRTA - Basque Research & Technology Alliance #CIBERehd are developing an innovative RNA-based therapy. This new treatment targets chronic liver diseases, a leading cause of global mortality exacerbated by rising obesity rates and alcohol abuse The therapy utilizes RNA to specifically target the magnesium transporter in liver cells, aiming to restore magnesium levels and improve liver health. Promising results have been observed in preclinical models for conditions such as alcoholic hepatitis, fatty liver disease, and fulminant liver failure 🚀 With support from Fundación ”la Caixa”, the team is moving forward with pilot batch production and regulatory phases to better understand the treatment's pharmacological behavior, pharmacokinetics, and safety. They’re also forging strategic partnerships with pharmaceutical and biotech companies to enhance the treatment’s visibility and development RNA is showing its potential to transform medicine and improve lives! #GeneExpression #Biotechnology #Health #Disease #MolecularBiology #Genetics #RNAResearch
To view or add a comment, sign in
-
Must read paper for prospective students who are intersex in drug discovery. A good example of case study to be incorporated in Medicinal Chemistry curriculum at undergraduate and postgraduate levels. #medicinalchemistry #curriculum #pharmacy #pharmaceuticalsciences
One of the best Med Chem paper that describes the process for identifying a biological target, identifying the hit/lead compound using computational methods and the proof-of-concept for confirming the activity of the compound. This paper can be considered as a case study for developing personalized medicines. This paper describes the process of developing personalized medicine for the individuals who are inherited with ApoE4 and highly susceptible for developing Alzheimer’s disease. #medicinalchemistry #drugdiscovery #drugdevelopment #alzheimersdisease #pharmaceuticalsciences
Rescue of ApoE4-related lysosomal autophagic failure in Alzheimer’s disease by targeted small molecules
nature.com
To view or add a comment, sign in
-
BD Rhapsody goes spatial 👀. Read a summary of the study at: https://lnkd.in/dRQDGZ6N #BDBiosciences #SingleCellAnalysis #SingleCell #SpatialBiology #Rhapsody #BD
The new Fragment Sequencing approach developed by researchers at ETH Zurich is opening up new insights into single-cell transcriptomics, and expanding the scope of what we know about cell-to-cell interaction, disease progression and tumorigenesis. Read our summary of the study to learn more : 👉 https://lnkd.in/dRQDGZ6N #BDBiosciences #SingleCellAnalysis #SingleCell #SpatialBiology #Rhapsody #BD
To view or add a comment, sign in
-
The new Fragment Sequencing approach developed by researchers at ETH Zurich is opening up new insights into single-cell transcriptomics, and expanding the scope of what we know about cell-to-cell interaction, disease progression and tumorigenesis. Read our summary of the study to learn more : 👉 https://lnkd.in/dRQDGZ6N #BDBiosciences #SingleCellAnalysis #SingleCell #SpatialBiology #Rhapsody #BD
To view or add a comment, sign in
-
📢 We are excited to present our new collection, "Exploring Novel In Vitro Models for Cystic Fibrosis Research," now open for submissions! 🚀🔬 https://lnkd.in/d75Z3Rkq Cystic fibrosis (CF) is a complex genetic disorder affecting the respiratory and digestive systems, often leading to chronic lung inflammation and pathogen infections. Current animal models face limitations in replicating CF's human complexities, highlighting the need for innovative in vitro approaches. With the recent approval of the “FDA Modernization ACT 2.0,” the use of complex in vitro cultures for drug testing is now a reality, offering more accurate research alternatives. This collection, led by Dr. Roberto Plebani, Dr. Yuncheng M. and, Dr. Domenico Mattoscio, welcomes articles focusing on novel in vitro models for CF research, with a particular interest in papers exploring 3D in vitro models, like organoids and organ-on-a-chip technology, which can enhance drug delivery predictions and provide insights into inflammation dynamics. 📃 Register your interest here: https://lnkd.in/di2q-s58 Manuscript Submission Deadline: 31 January 2025 #CysticFibrosis #CFResearch #InVitroModels #Organoids #OrganOnAChip #DrugDiscovery #Pharmacology #Research #InnovativeScience
To view or add a comment, sign in
-
The new Fragment Sequencing approach developed by researchers at ETH Zurich is opening up new insights into single-cell transcriptomics, and expanding the scope of what we know about cell-to-cell interaction, disease progression and tumorigenesis. Read our summary of the study to learn more : 👉 https://lnkd.in/dRQDGZ6N #BDBiosciences #SingleCellAnalysis #SingleCell #SpatialBiology #Rhapsody #BD
To view or add a comment, sign in
8,053 followers