Yale Child Study Center’s Post

#ThrowbackThursday In 2018, the Comet supercomputer was used by UC San Diego School of Medicine researchers to accelerate the processing and analysis of whole human genomes to detect variants in non-coding #DNA that contribute to inherited autism risk. The findings, published in #Science, are led by Jonathan Sebat, a professor of #psychiatry, cellular and #molecular #medicine, and #pediatrics.

When challenged with trying to help a nonverbal Autistic child become more verbal, one needs to become a “detective” to find out the best combination of therapies that will be most efficacious. The cases I will present share some of the multiple pathways in which I utilize to help reverse the negative traits of ASD and its complications. At the same time, one needs to support the person’s health needs nutritionally to become more neurotypical, have better bowel function, and improve his/her speech capabilities. Join us to hear David Dornfeld DO, speak to our MAPS in Clinical Practice attendees on this intriguing case study. https://lnkd.in/edES22Ji #speechtherapy #speechpathology #speech #asd #apraxia #integrativemedicine #hyperbaricoxygentherapy #conference2024 #specialneeds #pediatrics #neuroscience

MAPS is honored to have Dr Richard Frye, MD, PHD, FMAPS back at our Spring Conference this year! The title of his presentation is: LOCKED-IN NETWORK SYNDROME: FUNCTIONAL RESTING STATE MRI REVEALS INTACT FUNCTIONAL LANGUAGE NETWORKS IN MINIMALLY VERBAL CHILDREN WITH AUTISM SPECTRUM DISORDER Abstract: Resting state functional magnetic resonance imaging (rs-fMRI) has the potential to investigate abnormalities in brain network structure and connectivity on an individual level in neurodevelopmental disorders such as autism spectrum disorder (ASD), paving the way to use this technology for a personalized, precision medicine approach to diagnosis and treatment. For more information on this fascinating lecture, go to the link below. https://lnkd.in/edES22Ji save 20% off by using the code: MAPS2024IN #MAPS #CME #medicalconference #doctor #medmaps #medical #physician #medicaleducation #medicalnews #medicalcme #functionalmedicine #S2C #functionalmedicinedoctor #autoimmunity #translationalmedicine #CMEcredits #neurology #environmentalmedicine #specialneeds #pediatricscme #pediatrics #pediatrician #nurses #integrativehealth #lymedisease #neuropsychiatricspmptoms #downsyndrome #lockedinnetworksyndrome

New procedures for Alzheimer’s (and PANS, PANDAS, ASD?!?) My home state of WV and the WVU Rockefeller Neuroscience Institute (RNI) is pioneering research on memory disorders which may have impacts in the field of Alzheimer’s as well as Autism. WV has one of the highest rates of Alzheimer’s in the US.  Our family is part of this statistic. The team at RNI is studying noninvasive methods such as focused ultrasound, which directs an array of ultrasound beams into the brain to open the blood-brain barrier, the biological seal that limits potential treatments from reaching the targeted area of the brain. When the barrier is temporarily opened, medication can be safely delivered to the specific area of the brain where it’s needed. As the RNI researchers state, “The blood-brain barrier has long presented a challenge in treating the most pressing neurological disorders. The ability to non-invasively open the blood-brain barrier in the brain offers a new potential in developing treatments for Alzheimer’s disease.” In my opinion, this research could also have tremendous implications for those with ASD, PANS, PANDAS!  Stay tuned… https://lnkd.in/eT8MKWjD #alzheimers #PANS #PANDAS #BGE #ASD #autism #pediatrics #pediatrician #functionalmedicine

https://lnkd.in/gHwNECvN       Article title: The complex sexuality of “Italian” Hikikomori and the need for better nosographic framing of psychopathological evidence   Author(s): Giulio Perrotta* and Domenico Piccininno   Journal: Open Journal of Pediatrics and Child Health   Journal ISSN: 2640-7612 Abstract: Objective: The definition of “hikikomori” evokes dysfunctional personality pictures already known in the literature and medical practice. The aim is to refute the hypothesis of the need to identify this clinical condition in a new descriptive framework.   Materials and methods: Pubmed checklist, clinical interview, and psychometric tests.   Results: In the entirety of the selected population, it emerges that the primary disorder is schizoid personality disorder; this is followed by depressive disorder, narcissistic covert disorder, bipolar disorder with depressive prevalence, obsessive disorder, avoidant disorder, and somatic disorder as secondary dysfunctional personality traits. Childhood and/or family trauma, capable of impacting the sexual and affective sphere, is present in almost the entire population.   Conclusion: The syndrome should be framed as a specific phenomenon and not as a new psychopathological disorder, as the symptomatological descriptions are similar to the already known schizoid personality disorder; the symptomatological differences among patients should be framed according to a logic of correctives determined by the presence of one or more secondary psychopathological traits that draw a more complex personality picture than the simple nosographic diagnosis of the DSM-V.   #Hikikomori #Sexuality #SchizoidPersonalityDisorder-19 #PICI-2 #PediatricHospitalistMedicine #DevelopmentalPediatrics #MedicalGenetics #Neonatology #PediatricAllergology #PediatricDermatology #PediatricDiabetes #PediatricRespirology #PediatricIntensiveCare #GeneralPediatrics #TropicalPediatrics #TranslationalPediatrics #PediatricTransplantation #PediatricDrugs #AdolescentMedicine #AllergyAndImmunology #PediatricCardiology #PeertechzPublications #CriticalCareMedicine #DevelopmentalBehavioralMedicine #PediatricEndocrinology #PediatricGastroenterology #PediatricHematologyOncology #PediatricInfectiousDiseases #NeonatalPerinatalMedicine #PediatricNephrology #Peertechz #PediatricNeurology #PediatricEmergencyMedicine #PediatricPulmonology #PediatricRheumatology #PediatricGenetics #PediatricEthics #HealthServiceResearch

How do EMS providers cope with cognitive load during #pediatric #cardiacarrest?🫀 For emergency medical services (EMS) responders, this rare and challenging situation means high cognitive load while performing complex tasks under high stress and time pressure. Two new studies by Bahr et al. and Ivankovic et al. used fNIRS to measure the cognitive load of EMS providers during pediatric cardiac arrest scenarios. The results showed a high cognitive load during key tasks. The findings suggest fNIRS is a useful tool in measuring cognitive load in real-life/naturalistic scenarios and during activities that require freedom to move. Curious to know more? Check out the articles: https://lnkd.in/gDFHCT46 https://lnkd.in/gmEShWB3 #fNIRS #neuroscience #Appliedscience #OctaMon

PhysioTherapist: Exercises is Lifestyle

https://lnkd.in/gq3XfCdM       Article title: New Evolutionary Model on “Autistic Spectrum Disorder” (PEMA), the severity scale (PASS), and the clinical questionnaire for the late teenage years and adults (PTAS-Qa)   Author(s): Giulio Perrotta*   Journal: Open Journal of Pediatrics and Child Health   Journal ISSN: 2640-7612 Abstract: Starting from the concept of “Autism Spectrum Disorder”, as framed in the DSM-V, the present research proposes a new etiological theory (PETA) focused on the evolutionary model of the neurobiological matrix, overcoming the modest or inconsistent psychodynamic or conspiracy theses present in the international scene. Based on this assumption, therefore, a new study model (PEMA) was suggested that can focus on the presence or absence of 9 dysfunctional traits (type-deficit and type-clinical features) centered on the areas of social, emotional, and cognitive-communication and interaction, grading the impairment according to a precise 5-level severity scale (PASS), underpinning the 40-item questionnaire (Perrotta Dysfunctional Traits of the Autistic Spectrum Questionnaire for the late teenage years and Adults, PTAS-Qa) on a binary Y/N scale and based on a total score of 11/11, thus offering a more structured view of the patient’s cognitive and psychological organization, avoiding diagnostic fragmentations that might be inconsistent with the nosographic picture and therefore not perfectly framed. By exemplifying the category, it is, therefore, possible to more easily frame the patient, who would thus be analyzed from a strictly functional point of view, also facilitating the therapeutic interventions to be prepared, according to models already known in the literature (e.g. ABA).   #AutisticSpectrumDisorder #PEMA #PASS #PTAS-Qa #EvolutionaryModel #PediatricHospitalistMedicine #DevelopmentalPediatrics #MedicalGenetics #Neonatology #PediatricAllergology #PediatricDermatology #PediatricDiabetes #PediatricRespirology #PediatricIntensiveCare #GeneralPediatrics #TropicalPediatrics #TranslationalPediatrics #PediatricTransplantation #PediatricDrugs #AdolescentMedicine #AllergyAndImmunology #PediatricCardiology #PeertechzPublications #CriticalCareMedicine #DevelopmentalBehavioralMedicine #PediatricEndocrinology #PediatricGastroenterology #PediatricHematologyOncology #PediatricInfectiousDiseases #NeonatalPerinatalMedicine #PediatricNephrology #Peertechz #PediatricNeurology #PediatricEmergencyMedicine #PediatricPulmonology #PediatricRheumatology #PediatricGenetics #PediatricEthics #HealthServiceResearch

At the Academic Consortium for Integrative Medicine & Health, we work alongside our members as leaders and learners to advance whole health together through action and tangible impact.  In 2021, the Surgeon General of the United States and the American Academy of Pediatrics, the American Academy of Child and Adolescent Psychiatry, and the Children’s Hospital Association made a declaration of national emergency in child and adolescent mental health.  The Academic Consortium answered this call through successful nomination for PCORI funding support, and has created a Clinical Practice Guidelines (CPG) committee to develop a critical CPG on Mindfulness Interventions for Children and Youth.  In partnership with the American Academy of Pediatrics Section on Integrative Medicine leadership, Co-Chairs Sunita Vohra and Erica Sibinga lead the partnership with the Patient-Centered Outcomes Research Initiative (PCORI). PCORI will develop a systematic evidence review on Mindfulness-Based Interventions for Mental Health in Children and Adolescents that the Guideline Development Group will use to inform this clinical practice guideline. On the heels of the leadership of former CPG committee Co-Chairs, Suzanna Zick and Jeff Dusek PhD, CPG development will be further overseen by the Oversight Committee, composed of Sunita Vohra, Heather Boon, Lisa Susan Wieland and Ruth Q. Wolever, PhD.  Once established, the CPG will be disseminated to interested stakeholders including publishing the CPG in a high impact journal. We are honored to take part in this transformative work alongside these Champions of Whole Health.  ➡️Learn More: https://lnkd.in/gZSW5aRh #acimh #championsofwholehealth #clinicalpracticeguidelines #mentalhealth

🌟 Exciting news in Pediatric Epilepsy - https://bit.ly/4aL8CCN 🔍A recent study evaluated the effectiveness of integrated mental health treatment for children and young people with epilepsy, addressing common mental health challenges. 🧠 Discover how this intervention could positively impact pediatric epilepsy care. Stay tuned for more insights! Credit: Lancet 2024 #MentalHealth #Pediatrics #Epilepsy #Healthcare #Neurology #eMedEvents