Promega Ireland

NEW Product: Quantify Target Cell Killing with Confidence Introducing HiBiT Target Cell Killing (TCK) Bioassays—an innovative, highly specific method for precisely measuring biologic drugs where target cell lysis is a key mechanism of action. From CAR-T cells to bispecific and monoclonal antibodies, these assays deliver quantitative readouts with unmatched precision and flexibility. Their scalable workflow supports drug development from early discovery right through to commercial lot release, ensuring consistency across your programme. Plus, Raji, Ramos, and H929 HiBiT Target Cells are now available, with even more target and effector cell lines in Early Access! Learn more: https://bit.ly/41CETIZ #Bioassays #ImmunoOncology #CellKilling

Rapid, Same-Day Legionella Testing with Promega’s New GoTaq® Legionella qPCR Kits Promega’s GoTaq® Legionella qPCR Kits deliver fast, accurate, and reliable detection of Legionella spp., including L. pneumophila, providing results within hours instead of days. Ideal for water monitoring laboratories, these kits surpass traditional culture methods thanks to their high sensitivity and specificity. They’re also compatible with standard qPCR instruments and can be paired with Promega’s Viability PCR Reagent System to differentiate between viable and non-viable bacteria—reducing false positives. This ensures cost-effective, high-quality Legionella testing for more efficient water safety management. Learn more: https://bit.ly/4iuPSLI #LegionellaTesting #qPCR #PCR #reagents

Advancing Kinase Drug Discovery with Cellular Target Engagement Kinase inhibitors hold immense therapeutic promise, but selectivity remains a key challenge. A recent SLAS (Society for Laboratory Automation and Screening) Discovery highlights how live-cell assays like NanoBRET™ Target Engagement provide quantitative insights into compound binding and selectivity—crucial for optimising drug candidates. By assessing on-target vs. off-target effects in real time, these assays help streamline hit-to-lead optimisation and improve drug efficacy. If you’re interested in maintaining robust experimental design and reproducible results, this is a must-read. Read the full article: https://bit.ly/3FypX7o #BiochemicalAssays #SLASDiscovery #LifeSciences

Don’t forget—our free webinar is tomorrow, Wednesday, 12 March 2025 at 3.00 p.m. (GMT)! Topic: “Veterinary Diagnostics Simplified: Learn How to Automate High-Throughput Extraction” Speakers: o Subhanjan Mondal, PhD, Sr Research Scientist o Kirk Hetzel, Field Support Specialist o Michael Lisek, Segment Marketing Manager – Applied Markets We’ll cover strategies for streamlining nucleic acid extraction on automated platforms like Hamilton, Tecan, and Beckman Coulter, plus tips for building, validating, and troubleshooting high-throughput workflows. Register here: https://bit.ly/3FuASPc #PCR #biologics #VeterinarySciences

Catch up on the Undruggables 3-day virtual event. It was a fascinating lineup of speakers The videos of presentations are now available on demand (our website) Illuminating New Frontiers: Cracking the Undruggable Code" invites you on a groundbreaking journey across the evolving landscape of drug discovery. This three-day virtual event unites trailblazers in science and industry to explore how innovative approaches are reshaping our ability to tackle 'undruggable' targets. From the complexities of the RAS pathway and the intricacies of protein-protein interactions to the pioneering fields of targeted protein degradation/induced proximity and RNA targeting, each day illuminates a different frontier of therapeutic potential. We stand at the cusp of a new era, where challenges become opportunities for breakthroughs that extend beyond conventional boundaries. This event is a testament to the power of collaboration and innovation in unveiling new therapeutic strategies, offering hope for untreatable conditions. Join us as we navigate the cutting-edge of science, inspiring a future where every target is within our reach, and no patient is left without options.

Free Webinar: “Veterinary Diagnostics Simplified: Learn How to Automate High-Throughput Extraction” Join us next week, Wednesday, 12 March 2025 at 3.00 p.m. (GMT) for an expert-led forum featuring: o Subhanjan Mondal, PhD, Sr Research Scientist o Kirk Hetzel, Field Support Specialist o Michael Lisek, Segment Marketing Manager – Applied Markets Why attend? Advancements in molecular diagnostics are transforming veterinary medicine, companion animal health, and zoonotic disease surveillance. High-throughput, reproducible nucleic acid extraction is crucial yet challenging. Learn core principles of magnetic bead-based extraction and how to optimise your liquid handling platform (Hamilton, Tecan, Beckman Coulter, etc.). Discover proven strategies to build, validate, and troubleshoot high-throughput workflows. Register here: https://bit.ly/4kp8Uo2 #PCR #biologics #VeterinarySciences

✨ The GloMax® Galaxy Bioluminescence Imager is here in Ireland! Released at the start of this year, it’s designed to support your research with exceptional precision and clarity. Key features: • Optimised for NanoLuc® technologies • High sensitivity and resolution for real-time visualisation of protein interactions, cellular dynamics, and more • Reliable detail and performance for advanced applications Learn more: https://bit.ly/4hdJ5Vu #LabInstruments #CellularImaging #Bioluminescence #ResearchInnovation

Automation is revolutionising DNA engineering at the Edinburgh Genome Foundry Hear from Rennos Fragkoudis, on how Promega’s high-throughput plasmid DNA purification kit speeds up and simplifies their workflow. In this short video, learn how they extract 96 samples in just 45 minutes with minimal hands-on time (the full case study video is available on our YouTube channel). #DNAEngineering #EdinburghGenomeFoundry #HighThroughput

Have you seen the Promega blog post on Branched-Chain Amino Acids (BCAAs)? BCAAs are gaining attention in scientific research due to their pivotal roles in metabolic regulation, muscle protein synthesis, and cellular signalling pathways. Recent studies suggest BCAAs may influence metabolic diseases, ageing, and immune function, making them a fascinating area of exploration for a variety of research fields. Read our whistle-stop tour here: https://bit.ly/4kj4wXA #BCAAs #AminoAcids #MetabolicResearch #LifeSciences

We've created a webpage for Front Line Genomics #FoG2025, featuring genomic technical data and educational materials in one convenient place. ‘Mastering Genomic Workflows: Resources by Scientists, for Scientists’ offers practical insights and helps you tackle challenges in genomics—whether you joined the event or missed it. Take a look here: https://bit.ly/433NiHI #LifeSciences #Genomics