GeNeuro SA

Today we announced that the clinical trial against #postCOVID did not meet its primary endpoint. While these results are disappointing, GeNeuro will continue to analyze the data thoroughly to understand the results and explore potential insights.   GeNeuro thanks all the study participants, the investigators and all other site personnel for their commitment that made this novel study possible. The learnings from this study will certainly advance the knowledge of this new disease affecting millions of persons worldwide. https://lnkd.in/eqi8zXzg

GeNeuro is determined to develop GNK-301, an antibody designed to neutralize the #HERV-K ENV neurotoxin, which has been detected in the cerebrospinal fluid of patients with sporadic #ALS. This development is driven by the urgent need for effective treatments and the potential impact GNK-301 could have on improving patient outcomes. #ALS Awareness Day

New article from @kuerypatrick and team showing that W-ENV activates brain microglia and astrocytes fueling #smoulderingMS #temelimab, the anti #HERV W-ENV antibody developed by GeNeuro, has shown benefits on brain atrophy, myelin integrity and GAFP in #MS Phase II trials. https://lnkd.in/eYn9xp9s

Further evidence that #longcovid is a major public health problem affecting millions of patients #covidpersistente #postcovid #PASC https://lnkd.in/e_-PNv87

Congratulations to Patric Küry and team for their important article showing the effects of HERV-W on #MS-related smoldering neuroinflammation. #smolderingMS #HERVs https://lnkd.in/dei54MKE

Interesting article comparing cognitive and fatigue symptoms in #MS and #postCOVID patients. #HERV-W ENV has been found to be activated in both pathologies. #LongCovid #Covidpersistente #neurodegeneration https://lnkd.in/enYBgY7S

Further evidence on the important role of #HERV-W ENV in #MS #temelimab https://lnkd.in/eg72q4MC

Standing with the patients affected by this terrible disease, and hopeful that our efforts to develop a biomarker-based therapeutic solution will soon be fruitful. #LongCovidAwarenessDay #LongCovid #PostCovid #PASC #CovidPersistente #temelimab #HERVs

The evidence keeps building-up on the importance of #HERV-K ENV in #ALS.  GeNeuro's preclincal program is based on detecting this protein in patients and neutralizing its pathogenic effects. HERV-K (HML-2) envelope protein induces mitochondrial depolarization and neurotoxicity via endolysosome iron dyshomeostasis https://lnkd.in/eNgDTgPB