European Keto Live Centre

Wie Kohlenhydrate deinen Blutzucker bei Keto beeinflussen Video auf YouTube ansehen: https://lnkd.in/d5EHAz5u In dieser Episode klären wir die Glucose- und Insulinreaktionen nach kohlenhydratreichen Mahlzeiten auf und erläutern, warum Blutzuckeranstiege bei einer ketogenen Diät normal sind. Entdecke die neuesten wissenschaftlichen Erkenntnisse zur Keto-Ernährung und deren Auswirkungen auf deinen Stoffwechsel. #KetoDiät #Blutzucker #ErnährungWissenschaft #GesundeErnährung #StoffwechselFlexibilität #Insulinreaktion #Kohlenhydrate #KetoErkenntnisse #GesundLeben #WissenschaftUndEssen

I'm glad to see this newly published review article that highlights the truly sinister component of type 2 diabetes--hyperinsulinemia (i.e., elevated insulin; #insulinresistance). As much as the clinical focus of T2D has been centered on glucose, that's a later component that has a more modest contribution to chronic disease. If you want to know why #type2diabetes increases the risk of #Alzheimers disease, #heartdisease , fatty liver disease, etc., look at the chronically elevated insulin, not the glucose. Furthermore, any clinical intervention that lowers the glucose by increasing insulin will inevitably promote both weight gain and higher mortality. In both of my books (Why We Get Sick & How Not To Get Sick), this is the central message. Again, glad to see other biomedical scientists coming to the same conclusion. https://lnkd.in/g7crTbRn

A preclinical paper just released adds to the growing body of evidence on ketogenic metabolic therapy for ADPKD and provides insight into the effects of fasting, TRE, and β-hydroxybutyrate as a stand alone intervention. Key points • Polycystic kidney disease leads to increased glycolysis and metabolic disorder • Ketogenic therapy may alter disease outcomes by addressing the central metabolic issue • Both fasting and time-restricted feeding slow or reverse disease progression in rodents • Study demonstrates that β-hydroxybutyrate alone recapitulates the benefits of fasting Torres, J.A. et al. (2024) ‘β-Hydroxybutyrate Recapitulates the Beneficial Effects of Ketogenic Metabolic Therapy in Polycystic Kidney Disease’, iScience, p. 110773. Available at: https://lnkd.in/dN2s8VUA. This recent review looking at the ketogenic diet for kidney disease concludes this approach 'can be safely prescribed in patients with T2D for treating and remitting diabetes even if they have underlying stage 2 or 3 CKD or reduced kidney function'. See the paper for a comprehensive overview of application and considerations. Athinarayanan, S.J. et al. (2024) ‘The case for a ketogenic diet in the management of kidney disease’, BMJ Open Diabetes Research and Care, 12(2), p. e004101. Available at: https://lnkd.in/dzdmHkFj. 'Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a genetic disorder characterized by the development and enlargement of multiple kidney cysts, leading to progressive kidney function decline…this review highlights the latest studies on the use of ketosis, through ketogenic dietary interventions (daily calorie restriction, intermittent fasting, time-restricted feeding, ketogenic diets, and exogenous ketosis), as a potential strategy for patients with ADPKD'. Pezzuoli, C.; Biagini, G.; Magistroni, R. Ketogenic Interventions in Autosomal Dominant Polycystic Kidney Disease: A Comprehensive Review of Current Evidence. Nutrients 2024, 16, 2676. https://lnkd.in/dVuQs-zn #kidneydisease #ADPKD #metabolichealth

GLP-1 receptor agonists, like Ozempic, are shaking up the weight loss game. But beyond the buzz, they present fascinating scientific questions that researchers are eager to explore. 🧠 HOW do GLP-1s affect the brain to reduce cravings? 🤢 WHY does Ozempic cause nausea, and can we mitigate this using neuroscience? 🔥 WHAT quirks of physiology give newer drugs their edge over Ozempic? 🍽 HOW can we address GLP-1 deficits in obesity and metabolic syndrome at the root, i.e. with diet and lifestyle interventions as a primary obesity treatment strategy and/or pharmacotherapy adjuct? Setting aside cultural debates, there’s a lot of intriguing physiology to uncover here! Let’s dive in with a scientific lens👇 #MetabolicHealth #WeightLossScience #Pharmacology #HealthInnovation #ScientificDiscovery https://lnkd.in/e7tT5MuG

My recent conversation with Eric C. Westman MD MHS - a pioneer in the field of metabolic medicine and the first doctor to discover that a #ketodiet could put serious psychotic symptoms into remission in 2009. How far the field of metabolic psychiatry has since come! We share patient stories, discuss my new book, and reflect on the latest developments in the exciting field of #metabolicpsychiatry. 🧠