Stammzellnetzwerk.NRW

StN Spotlight series double feature on October 17: Dr. Sarah Rieck Rheinische Friedrich-Wilhelms-Universität Bonn will give a talk entitled "Rapid, reproducible and cost-effective generation of highly enriched endothelial cells by forward programming of hiPSCs via ETV2" and Dr. Kristin Glotzbach, Ruhr-Universität Bochum & Ralf Weberskirch, Technische Universität Dortmund will tell you more about "How cationic charged Hydrogels modulate Neural Stem and Progenitor Cell Behavior”. Looking forward for many of you to join. https://lnkd.in/eJrEQ4P

Very happy to share that our manuscript entitled "Reassessment of marker genes in human induced pluripotent stem cells for enhanced quality control" has been published in Nature Communications! 🎉🥳 Huge congratulations to Jochen Dobner for leading this fantastic work, and special thanks to our great collaborators Alessandro Prigione and Sebastian Diecke! In this study, we leveraged long-read nanopore sequencing to identify 172 new genes associated with iPSC cell states, many of which are absent from current guidelines. We validated 12 unique markers across pluripotency, endoderm, mesoderm, and ectoderm, and developed hiPSCore, a machine learning-based tool that improves iPSC quality control by providing faster and more reliable assessments. hiPSCore accurately classifies pluripotent and differentiated cells and predicts their potential to become specialized 2D cells and 3D organoids. This is a major step forward in ensuring more precise and efficient pluripotency testing, benefiting both scientific research and clinical applications. You can test hiPSCore here: https://lnkd.in/eC4UNS7n International Society for Stem Cell Research Stammzellnetzwerk. NRW German Stem Cell Network (GSCN) Oxford Nanopore Technologies #StemCells #iPSCs #NanoporeSequencing #MachineLearning #QualityControl #Pluripotency #Organoids #RegenerativeMedicine #NatureCommunications #hiPSCore https://lnkd.in/eW-sNKGt

👩🏫 Hey bioinformaticians: we need your help. Join our team now! We offer a position for a bioinformatician working on epigenetics of pluripotent stem cells and aging. Please share this information!

Don't miss the upcoming StN Spotlight talks with Eleni Papanikolaou, Miltenyi Biotec on September 19 and the Double Feature on October 17 with Dr. Sarah Rieck Rheinische Friedrich-Wilhelms-Universität Bonn and Dr. Kristin Glotzbach, Ruhr-Universität Bochum & Ralf Weberskirch, Technische Universität Dortmund

It's out! So happy to share our latest work in Nature Communications. We studied the impact of mutant Huntingtin -causative of #Huntington disease- on human neurodevelopment using brain organoid models. We found that CHCHD2 is early disregulated leading to mitochondrial defects. So CHCHD2 may represent a new interventional target. This was a long project starting quite some years ago and an huge collaborative efforts! Mainly with University of Düsseldorf and Max Delbrück Center but also other labs! Wonderful work from co-first authors Pawel Lisowsky and Selene Lickfett, and co-last author Jakob Metzger. Thanks to all coauthors! https://lnkd.in/egj5dAXP

Join our next StN Spotlight talk on Thursday, August 15, 1 pm by Dr. Kristin Glotzbach and Ralf Weberskirch to find out "How cationic charged Hydrogels modulate Neural Stem and Progenitor Cell Behavior" https://lnkd.in/eJrEQ4P

BioRiverBoost! - celebration - applicants BioRiver Boost! is the prestigious #competition for lifescience #startups and founding projects to win the #feedback and the attention of the #lifescience #industry. Organized by BioRiver to support #founders and to #boost #innovation.   👉 Online application: https://lnkd.in/ef4BmEB5   🏆 The perfect #applicant ?How will you #make #money? incl. #marketneed #businessmodel #team ?What precisely is #unique about your #technology? >all #lifesciences and #biotech >in 2024 special in #immunology, #neurology and #oncology. >regional, national, European startups >startups before, during or shortly after registration as GmbH (app. 2 years before to 2 years after, but there is no limitation set) will have the best benefit for their development if you can answer the above #questions well and fill in the further requirements - you are #ready to apply. 👉 Online application: https://lnkd.in/ef4BmEB5 👨⚖️ 👩⚖️ The BioRiver Boost! jury 2024: Bettina Moeckel (PhD) Anthony Gemmell Ralf Angermund Mariette Mohaupt Dr. Volker Vogel Anna-Lisa Picciolo-Lehrke Karl-Heinz Schneider Karl D Collins Dr. Thomas Raueiser Marek Kozlowski, PhD MScEng Caroline Fichtner & #businessangels 📆Important dates 26.08. End of the #applicationperiod 14.09. Notification of the selected 8 finalists by the jury 18.09. Pitchtraining for finalists 27.09. BioRiverBoost! event, hosted by Johnson & Johnson, Neuss, including pitch- and q&a sessions, reverse pitches, networking and award ceremony for the best startups   Startup-NRW.event The BioRiver Boost! closing event is kindly supported by the Ministerium für Wirtschaft, Industrie, Klimaschutz und Energie des Landes NRW #DWNRW.   Sponsors We thank our sponsors for their valuable financial and in kind contribution: Host: Johnson&Johnson, Platin: Duesseldorf Economic development department, KölnBusiness WIrtschaftsförderungsGmbH, Gold: NRW.Bank. All sponsors see https://lnkd.in/e7Mdxp44. If you are interested to become #sponsor please contact the BioRiver office. #bioriver #biotech #startups #competition #lifesciences #immunology #neurology #oncology and all other fields in biotech and life sciences 👉 Online application: https://lnkd.in/ef4BmEB5 Life Science startups – APPLY NOW!

Join our team now! We offer a position for a bioinformatician working on epigenetic characterization of pluripotent stem cells. Please share this information! (P.S.: There is also a vacant PhD position of epigenetics of CAR T cells)

Interested to get insights sinto the HEAL EU Project? Then join the StN Spotlight talk by Fabienne Becker from the Heinrich-Heine-Universität Düsseldorf (research group Gesine Koegler) on Thursday July 18, 1 pm. https://lnkd.in/eJrEQ4P

🚨 🚨 𝐕𝐞𝐫𝐥ä𝐧𝐠𝐞𝐫𝐭𝐞 𝐄𝐢𝐧𝐫𝐞𝐢𝐜𝐡𝐮𝐧𝐠𝐬𝐟𝐫𝐢𝐬𝐭 𝐟ü𝐫 𝐙𝐮𝐤𝐮𝐧𝐟𝐭𝐁𝐈𝐎.𝐍𝐑𝐖! 🚨 🚨 Wir freuen uns, bekannt geben zu können, dass die Einreichungsfrist für Projektskizzen im Rahmen von ZukunftBIO.NRW bis zum 𝟹𝟷.𝟶𝟽.𝟸𝟶𝟸𝟺 verlängert wurde! 🌿💡 Hier noch einmal alle wichtigen Infos zu dem Förderaufruf. Nordrhein-Westfalen als Spitzenstandort der Biotechnologie: Unter dem Dach ZukunftBIO.NRW fördert das Ministerium für Wirtschaft, Industrie, Klimaschutz und Energie des Landes NRW biotechnologische Entwicklungen mit den Schwerpunkten biobasierte Industrie und Zukunftsmedizin. 💶 Förderprogramm für KMU und Start-Ups: Das Programm richtet sich vorrangig an KMU und Start-Ups. Darüber hinaus sollen auch Hochschulen und Forschungseinrichtungen in NRW ihr innovatives Potential einbringen, um zukunftsweisende Ideen umzusetzen. ⏰ 𝐕𝐞𝐫𝐥ä𝐧𝐠𝐞𝐫𝐭𝐞 𝐄𝐢𝐧𝐫𝐞𝐢𝐜𝐡𝐮𝐧𝐠𝐬𝐟𝐫𝐢𝐬𝐭: Interessierte Unternehmen und Forschungseinrichtungen haben nun die Möglichkeit, ihre Projektskizze digital bis zum 𝟹𝟷.𝟶𝟽.𝟸𝟶𝟸𝟺 beim Projektträger Jülich (PtJ) hier einzureichen: https://lnkd.in/ewRsWYci 🌾 Biobasierte Industrie: Der Förderaufruf „Biobasierte Industrie“ erkennt die Schlüsselrolle an, die der Aufbau einer biobasierten Industrie auf dem Weg zur Klimaneutralität spielt. Durch innovative Nutzung von biobasierten Rohstoffen und Recycling biologischer Produkte kann die Unabhängigkeit von fossilem Kohlenstoff erreicht werden. Anwendungen aus unterschiedlichen Branchen sind willkommen. 🩺 Zukunftsmedizin: Der Förderaufruf „Zukunftsmedizin“ zielt darauf ab, die allgemeine Gesundheitsversorgung durch personalisierte Medizin zu verbessern, die individuell abgestimmte Diagnostik und Therapien ermöglicht. Neu ist der stärkere Fokus auf biomedizinische Anwendungen wie Zell- und Gentherapie sowie Projekte, die geschlechterspezifische Erkrankungen adressieren. Weitere Informationen finden Sie hier: https://lnkd.in/e36YyWDM Nutzen Sie diese Chance, Ihre innovativen Lösungen voranzubringen! 🚀 Ministerium für Wirtschaft, Industrie, Klimaschutz und Energie des Landes NRW / Michael Massow / Carina Balduin / Projektträger Jülich, Forschungszentrum Jülich GmbH #BIONRW #ZukunftBIONRW #Innovation #Biotechnologie #Förderung #NRW #BiobasierteIndustrie #Zukunftsmedizin