Kuhner Shaker B.V.

Extra, extra! On the 27th of November 2024 EnzyScreen, Kuhner Shaker and Marcel Vieira-Lara (TU Delft) will host a Shaking Day Seminar at the TU Delft. Questions discussed will be: - What shaking parameters should I choose for my microplates cultures? - Reproducibility issues in shaken culture results, what are causes? - The scale-up from shake flask into stirred vessel, what's the issue? - Baffles, working volume, shaking diameter, stopper type, well geometry, why and how does it influence shake flask cultures? - How can I simulate a large-scale fed-batch process on a small-scale? If you would like to join, please register using the QR code below. Costs are associated for participants from industry, registration possible until 10th of November 2024.

🔎 𝐂𝐡𝐞𝐜𝐤 𝐨𝐮𝐭 𝐨𝐮𝐫 𝐭𝐞𝐚𝐬𝐞𝐫 𝐯𝐢𝐝𝐞𝐨 𝐚𝐧𝐝 𝐝𝐢𝐬𝐜𝐨𝐯𝐞𝐫 𝐨𝐮𝐫 𝐧𝐞𝐰, 𝐟𝐮𝐥𝐥𝐲 𝐚𝐮𝐭𝐨𝐦𝐚𝐭𝐞𝐝 𝐌𝐢𝐜𝐫𝐨𝐏𝐥𝐚𝐭𝐞 𝐒𝐡𝐚𝐤𝐞𝐫 𝐌𝐏𝐒-𝐙! 𝐓𝐡𝐞 𝐩𝐞𝐫𝐟𝐞𝐜𝐭 𝐬𝐨𝐥𝐮𝐭𝐢𝐨𝐧 𝐟𝐨𝐫 𝐲𝐨𝐮𝐫 𝐥𝐚𝐛 𝐨𝐟 𝐭𝐡𝐞 𝐟𝐮𝐭𝐮𝐫𝐞! Kuhner shaker’s brand-new and innovative 𝐦𝐢𝐜𝐫𝐨𝐩𝐥𝐚𝐭𝐞 𝐬𝐡𝐚𝐤𝐞𝐫 𝐌𝐏𝐒-𝐙 is the reliable cultivation system for your automated bioprocess: 🔹 Transfer platform with barcode reader allows for seamless integration into a liquid handling or automation platform. 🔹Self-developed SCARA system “Hawk” enables smooth process workflows with short access times. 🔹High-precision control of all essential cultivation parameters: temperature, humidity, shaking speed, and CO2. 🔹Operates up to 16 microtiter plates. 🔹Easy and fast changes of the shaking diameter (3, 6, 12.5, 25, or 50 mm). 🔹Strong, long-lasting & maintenance-free direct drive offers high shaking frequencies up to 1000 rpm (at 3 mm shaking diameter) 🔹Robustness: all MPS-Z components are of high quality and designed for durability and reliability. 🔹Ready for the future: two communication protocols, the state-of-the-art protocol TCP/IP and the new standard for lab automation, SiLA 2 (HTTP/2).   𝑽𝒊𝒔𝒊𝒕 𝒖𝒔 𝒂𝒕 𝒕𝒉𝒆 𝒇𝒐𝒍𝒍𝒐𝒘𝒊𝒏𝒈 𝒕𝒓𝒂𝒅𝒆 𝒇𝒂𝒊𝒓𝒔 𝒕𝒐 𝒔𝒆𝒆 𝒕𝒉𝒆 𝑴𝑷𝑺-𝒁 𝒊𝒏 𝒂𝒄𝒕𝒊𝒐𝒏:   📍 ESACT - European Society for Animal Cell Technology Meeting 2024 in Edinburgh from June 23-26, 𝐛𝐨𝐨𝐭𝐡 𝟔𝟏   📍 Future Labs Live Basel from June 26-27, 𝐛𝐨𝐨𝐭𝐡 𝟏𝟏𝟑   𝑊𝑒 𝑙𝑜𝑜𝑘 𝑓𝑜𝑟𝑤𝑎𝑟𝑑 𝑡𝑜 𝑚𝑒𝑒𝑡𝑖𝑛𝑔 𝑦𝑜𝑢! #kuhnershaker #automation #bioprocess #microtiterplate

𝐖𝐨𝐮𝐥𝐝 𝐲𝐨𝐮 𝐥𝐢𝐤𝐞 𝐭𝐨 𝐡𝐚𝐯𝐞 𝐚 𝐫𝐞𝐥𝐢𝐚𝐛𝐥𝐞 𝐚𝐧𝐚𝐥𝐲𝐬𝐢𝐬 𝐭𝐨𝐨𝐥 𝐭𝐨 𝐞𝐯𝐚𝐥𝐮𝐚𝐭𝐞 𝐚𝐧𝐝 𝐜𝐨𝐦𝐩𝐚𝐫𝐞 𝐭𝐡𝐞 𝐠𝐫𝐨𝐰𝐭𝐡 𝐚𝐧𝐝 𝐩𝐫𝐨𝐝𝐮𝐜𝐭 𝐟𝐨𝐫𝐦𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 𝐝𝐢𝐟𝐟𝐞𝐫𝐞𝐧𝐭 𝐬𝐭𝐫𝐚𝐢𝐧𝐬? 𝐎𝐫 𝐰𝐨𝐮𝐥𝐝 𝐲𝐨𝐮 𝐥𝐢𝐤𝐞 𝐭𝐨 𝐭𝐞𝐬𝐭 𝐝𝐢𝐟𝐟𝐞𝐫𝐞𝐧𝐭 𝐦𝐞𝐝𝐢𝐚 𝐜𝐨𝐦𝐩𝐨𝐬𝐢𝐭𝐢𝐨𝐧𝐬 𝐚𝐧𝐝 𝐜𝐚𝐫𝐛𝐨𝐧 𝐬𝐨𝐮𝐫𝐜𝐞𝐬 𝐭𝐨 𝐟𝐢𝐧𝐝 𝐨𝐮𝐭 𝐰𝐡𝐢𝐜𝐡 𝐩𝐞𝐫𝐦𝐢𝐭𝐬 𝐭𝐡𝐞 𝐛𝐞𝐬𝐭 𝐠𝐫𝐨𝐰𝐭𝐡 𝐚𝐧𝐝 𝐩𝐫𝐨𝐝𝐮𝐜𝐭 𝐟𝐨𝐫𝐦𝐚𝐭𝐢𝐨𝐧 𝐟𝐨𝐫 𝐲𝐨𝐮𝐫 𝐨𝐫𝐠𝐚𝐧𝐢𝐬𝐦?   Austrian biotechnology company Bisy[LR1]  – Biology for Synthesis – which offers customized solutions for Pichia pastoris / Komagataella phaffii protein expression and strain development uses 𝐭𝐡𝐞 𝐊𝐮𝐡𝐧𝐞𝐫 𝐓𝐎𝐌 𝐒𝐲𝐬𝐭𝐞𝐦 to evaluate and analyze the growth and product formation of their P. pastoris / K. phaffii expression system. For instance, on the attached poster you can find scientific data of the comparison of two different K. phaffii strains which were grown in batch culture on glucose, glycerol, and methanol as sole carbon source in shake flasks. Two of the key enzymes of the methanol utilization pathway (Mut) are the alcohol oxidases 1 and 2. In this study, a Mut+ strain expressing both, AOX1 and AOX2, and a MutS (Methanol utilization slow) strain only expressing AOX2 were compared. The growth physiology was analyzed with 𝐭𝐡𝐞 𝐊𝐮𝐡𝐧𝐞𝐫 𝐓𝐎𝐌 𝐒𝐲𝐬𝐭𝐞𝐦, measuring oxygen transfer rate (OTR), carbon dioxide transfer rate (CTR) and respiratory quotient (RQ).   Check out the poster for more scientific data: https://url-r.fr/kPQKs   𝑴𝒐𝒓𝒆 𝒊𝒏𝒇𝒐𝒓𝒎𝒂𝒕𝒊𝒐𝒏 𝒐𝒏 𝒕𝒉𝒆 𝑲𝒖𝒉𝒏𝒆𝒓 𝑻𝑶𝑴 𝑺𝒚𝒔𝒕𝒆𝒎: https://lnkd.in/ef4HmSVp   #kuhnershaker #shakeflask #onlinemonitoring #processdevelopment #pichia #proteinexpression

𝐊𝐮𝐡𝐧𝐞𝐫 𝐅𝐞𝐞𝐝𝐢𝐧𝐠 𝐓𝐞𝐜𝐡𝐧𝐨𝐥𝐨𝐠𝐲 𝐞𝐱𝐩𝐚𝐧𝐝𝐬 𝐰𝐢𝐭𝐡 𝐧𝐞𝐰 𝐩𝐫𝐨𝐝𝐮𝐜𝐭: 𝐬𝐮𝐜𝐫𝐨𝐬𝐞 𝐟𝐞𝐞𝐝𝐢𝐧𝐠 𝐟𝐨𝐫 𝐩𝐥𝐚𝐧𝐭 𝐜𝐞𝐥𝐥 𝐜𝐮𝐥𝐭𝐢𝐯𝐚𝐭𝐢𝐨𝐧. We introduce sucrose for plant cell cultivations as a completely new substrate in our Feeding Technology portfolio. As a start, Feed Beads with 12 mm diameter for shake flask cultivations, Feed Plates with 96 round wells, and Feed Plates with 24 or 96 square wells are available with sucrose as slow-release fed-batch substrate. The products are available with different release rates of sucrose and have a linear release profile over the course of at least 96 hours. Adaptations of the release rates (to a certain extent) are possible, depending on the customer’s requirements. Please contact us for further information or if you have any Feeding Technology related questions: deoffice@kuhner.com. Please also take a view on our website: https://lnkd.in/dVhTcsj   #kuhnershaker #biotechnology #bioprocess #feedingtechnology #fedbatch #shakeflask #microtiterplate #MTP #plantcells #cellculture #processdevelopment #customized

Marcel Passon, congratulations on your great results and nice poster at the PBP world meeting! We are happy to have been able to support your work with the Kuhner #OrbitallyShakenBioreactor

The Kuhner shaker family wishes you a 𝑯𝑨𝑷𝑷𝒀 𝑬𝑨𝑺𝑻𝑬𝑹! 🐰🐣🌸 #kuhnershaker #kuhner #happyeaster

I am so excited to celebrate an incredible milestone for Kuhner Shaker this year. 75 Years delivering the highest quality products and services is certainly reason to celebrate! Follow along all year for many exciting events, collaborations, launches and BIG Giveaways!!! 2024 should be the best year yet!

A very inspiring seminar at the RTWH Aachen! A big thank you to #Enzyscreen, #RWTHAachen, and our visitors and speakers from industry and academia.

📣 Kuhner Shaker will hold the interesting seminar "Scientific and practical aspects of orbital shaking in biology" on the 11th of December in Aachen. A must to check out for BeNeLux researchers that work a lot with micro plate and shake flask cultures. And, maybe it's also a great excuse to visit those famous Aachen Christmas markets afterwards ☃ 😀

Kuhner Shaker is ready for a great week at the European Society of Gene and Cell Therapy Congress 2023 in Brussels (#ESGCT)! We are happy to meet you if you are there and to show our Shaken Cell Culturing solutions.