Symeres

Join the Symeres Team at the Pharma Partnering Summit 2024! We’re excited to announce that Symeres will be attending the Pharma Partnering Summit 2024, taking place from October 16-17th in Boston, MA. Our team, including Rory Curtis, Paul O'Shea and Russell Thomas, will be present, and we invite you to meet with us to discuss how we can support your drug discovery and development programs. Additionally, Paul O'Shea will be delivering a presentation titled: "The Role of CMC in IND Enabling Studies" 🗓 Date: October 16th, 2024 🕒 Time: 9:30 AM This summit brings together senior executives and decision-makers from across the globe to connect, explore new opportunities, and foster meaningful collaborations. We look forward to engaging with you during showcases, meetings, and networking sessions! #collaborations #fundraising #commercial #networking #pharmapartneringsummit

𝗖𝘂𝗿𝗶𝗼𝘂𝘀 𝘁𝗼 𝗸𝗻𝗼𝘄 𝗵𝗼𝘄 𝗺𝗶𝗥𝗡𝗔 𝗮𝗻𝗱 𝗹𝗶𝗽𝗶𝗱𝘀 𝗮𝗿𝗲 𝗰𝗼𝗻𝗻𝗲𝗰𝘁𝗲𝗱? The Nobel Prize in Medicine was recently awarded to Victor Ambros and Gary Ruvkun for their discovery of microRNA (miRNA), crucial for regulating genetic activity. miRNAs are small RNA molecules that bind to messenger RNA (mRNA), inhibiting protein synthesis or degradation. Even though all cells in the body contain identical DNA, it is through this mechanism that there are diverse cell types. miRNAs are also being explored as cancer therapies, functioning as tumor suppressors. Research is focused on safely delivering miRNA or mRNA using lipid nanoparticles, which enhance stability, intracellular delivery, better targeting and dose reduction. At Symeres, in conjunction with Organix, we specialize in: 1) Experience with MC3, a gold standard in ionizable lipids. 2) Production of cationic lipids, lipopeptides, lipoids, biodegradable lipids, arachidonyl lipids, and GalNAc derivatives. 3) Lipid scale-up capabilities, including GMP-compliant processes and the production of microspheres. Symeres has been supporting the global pharma and biotech industry with the synthesis and (ultra)purification of these novel lipids, such as those used in lipid nanoparticles used to deliver RNA-based therapeutics. #NobelPrize #Chemistry #𝗺𝗶𝗥𝗡𝗔 #Lipids #Symeres #CRO Learn more here: https://lnkd.in/eDbWcSrr

#SymeresPolls 🔬 Science is one of our passions. Our >500 researchers face new challenges every day. Their creativity and drive for discovery have helped us maintain our position as a leading CRO. While focusing on the commercial aspects of science, our scientists continually tackle challenges that spark interest across the scientific community. Today, we’d like to hear from you! What do you think is the most interesting unsolved mystery in chemistry right now? We've selected three intriguing options, but we've left the fourth one open for your suggestion in the comments section! 1)    What is the origin of homochirality in biomolecules? 2)    Why are accelerated kinetics observed for some organic reactions at the water-organic interface? 3)    Why do some enzymes exhibit faster-than-diffusion kinetics? 4)    Your option (leave your comments below)

Symeres is present at CPHI 2024 in Fiera Milano, Italy from Oct 8-10th. The Symeres team with Roger McDonald, Karen Damian, Kirill Kulish, Chris Teleha, André de Vries, Göran Verspui, and Russell Thomas look forward to meeting you there. Visit us at booth #5F90 or see you at the Symeres meeting room #5F87! We have soda waters available at our booth too for attendees.   Work with Symeres to leverage the expertise of our 500+ scientists to achieve your development goals. Operating from eight sites across Europe and the USA, we provide specialized support in Process Chemistry, Analytical Chemistry, Formulation Development, Quality Assurance, and Regulatory Affairs. Our full-service CMC Consulting and R&D Laboratories assist in all stages, from IND/IMPD processes to non-GMP scale-up, GMP manufacturing, and GMP starting material supply. With strengths in solid-state chemistry and pre-formulation research, we are also fully equipped to meet your formulation development and clinical manufacturing requirements.   Furthermore, Symeres has open positions in Technical/Operations and Business Development, please stop by booth #5F90 for a chat if interested! We look forward to connecting with industry peers, clients, and potential partners to explore collaborative opportunities in pharmaceutical development. CPHI is a key gathering for professionals involved in pharmaceutical development and manufacturing, offering extensive opportunities for networking and business growth: https://lnkd.in/d4JsqpU   #CPHI2024 #35thanniversary #manufacturing #pharma #impd #cmc #cro

Symeres is excited to participate for the first time at the 37th Annual Congress of the European Association of Nuclear Medicine (EANM) in Hamburg. Sascha Hartmann, Director of Business Development, and Ton Visser, Team Leader at Symeres, are thrilled to be part of this prestigious event. This congress is the perfect platform to engage with leading experts, clinicians, and researchers, exchanging cutting-edge insights and innovations in the field of nuclear medicine. We’re looking forward to the scientific sessions on topics like molecular imaging, radiopharmaceuticals, and theranostics. Curious about Symeres' expertise in the design and synthesis of precursors for positron emission tomography (PET) Interested in learning more about our expertise in labelling? Feel free to reach out to Ton and Sascha—they'll be happy to share more details! #EANM2024 #NuclearMedicine #Radiopharmaceuticals #Symeres #PET

Join Symeres’ US Business Development team at the PDDP in La Jolla, October 17-18! Our Business Development Directors, Bart DeCorte and Leah Haydock are excited to connect with partners and customers in the San Diego area for insightful discussions and new collaborations. Would you like to know about Symeres Drug Discovery and Development services? Curious about our expertise in small molecule R&D, or interested in our comprehensive ADME-Tox profiling and in vivo DMPK platforms? Don’t miss the chance to engage with Bart and Leah at the event or schedule a meeting in advance to discuss how Symeres can support your projects. #Symeres #Admescope #DrugDiscovery #DMPK #ADMETox

Symeres is happy to share that our very own Luc Van HIJFTE, the president of the EFMC - European Federation for Medicinal Chemistry and Chemical Biology, delivered a talk today at the RSC/SCI Symposium on GPCRs in Medicinal Chemistry in Verona, Italy titled ‘A New Dual Mode of Action to Treat Pain - From Scratch to Preclinical Candidate'. We hope that all the attendees enjoyed Luc's warm jokes and this informative lecture!

Creating a viable drug candidate can be a daunting task that requires an interdisciplinary approach of many various expertises. Often pharmaceutical or biotechnology companies do not contain all the required knowledge in-house or have the manufacturing capabilities.   At Symeres, we are able to offer a comprehensive range of CMC and ADME/Tox services to help facilitate your IND/IMPD filing and we provide more than just data by working closely with your team to identify program risks, propose mitigation strategies and coordinate future activities together. With our team of 600+ expert scientists across eight sites in the US/Europe, we can help identify challenges and find solutions for every step of the process. Symeres can provide both the data and knowledge to make sound decisions for your candidate molecules. You will work directly with our scientists every step of the way.   Interested in meeting our team? Symeres will be present at CPHI 2024 in Fiera Milano, Italy from Oct 8-10th. The Symeres team with Roger McDonald, Kirill Kulish, Karen Damian, Chris Teleha, André de Vries, Russell Thomas and Göran Verspui look forward to meeting you there. Visit us at booth #5F90! Furthermore, Symeres has open positions in Technical/Operations and Business Development, please stop by booth #5F90 for a chat if interested!  CPHI is a key gathering for professionals involved in pharmaceutical development and manufacturing, offering extensive opportunities for networking and business growth.    #development #drugs #cmcintegration #indimpd #cphi

Symeres is happy to announce that Sascha Hartmann will be present at "Highlights in Medicinal Chemistry V" organized by SCI's Fine Chemicals Group located in London, UK today. Come join to learn the latest in medicinal chemistry and connect with Sascha to learn more. Our organization specializes in helping with drug discovery from hit lead, hit-to-lead, lead optimization, computational chemistry, rapid analogue synthesis and integrated drug discovery. Our expert team of over 500+ scientists in Europe and the US can help you achieve your goals! Interested? Visit us at: https://lnkd.in/eDtYkuTd

Symeres will be present at BioJapan 2024, an event combined with Regenerative Medicine Japan and healthTECH Japan. Come meet the Symeres team Norimasa Morita and Luc Van HIJFTE! With our team of 500+ experienced scientists in eight locations in Europe and the USA, we offer expertise and provide services in drug discovery and drug development. Our services range from early stage hit finding all the way to delivery of your early clinical drug substance and drug product. Furthermore, we offer a comprehensive range of CMC and ADME/Tox Services that support IND/IMPD filing. This event will be Asia's largest partnering event consisting of three main programs: exhibition, seminar and partnering. Leaders from academia and industry gather here to discuss challenges, innovations and collaborative opportunities together in biopharmaceuticals and biotechnology sectors. We look forward to meeting you there! #partnering #cmc #discovery #PRD #drugdevelopability