Intelliseq

❓ Is a heterozygous variant of high pathogenicity with a reported recessive inheritance pattern sufficient to cause disease? ❓ What is the difference in predicting the likelihood of disease development when two pathogenic variants within a single gene are present on the same allele versus different alleles? What is compound heterozygosity? ✅ Learn how to resolve these complexities and how easy it is to obtain this information with the GeneSpect Hereditary Reporter → https://lnkd.in/gTff8DVV 

Whole Exome Sequencing (WES) and Whole Genome Sequencing (WGS) genomic analyses can be used to address a wide range of questions 🧬Applications can range from preventive screening for pathogenic variants to the identification of variants associated with rare diseases or cancer. Given the large amount of data involved, it is essential to define the scope of the analysis accurately to ensure that it addresses the specific clinical question. A critical step in this process is the creation of a customized panel of genes to be analyzed. It is essential to identify which genes or variants may be associated with specific conditions. This process may involve screening databases, scientific literature, and expert guidelines. Fortunately, you don't have to do this manually and all by yourself, find out the link to the full article in the comments section down below 👇

Discover how optimizing phasing in genotyping can improve PGx workflows. Our latest article reveals how accurate haplotype determination with advanced tools like Intelliseq Polygenic boosts precision in drug response predictions, ensuring optimal treatment plans🌟 🔗 Read the full article: https://lnkd.in/eM6cth34 #Pharmacogenomics #PersonalizedMedicine #Genotyping #Phasing

We were delighted to showcase our innovative solutions dedicated to pharmacogenetics and polygenic risk score analysis and reporting at BioMeeting 2024, where we had the opportunity to engage with industry leaders, young researchers, and professionals. The posters focused on solutions within the genomic data processing workflows integrated into our two cutting-edge products: the GeneSpect PGx Reporter and the GeneSpect PRS Reporter. Read more and view full posters here: https://lnkd.in/dw3bxAS3

Explore the complexities of translating phenotypes into clinically actionable recommendations in pharmacogenomics. Learn why PGx testing can guide personalized therapy - optimizing drug dosing and minimizing side effects. See practical examples and learn about Intelliseq's innovative GeneSpect PGx Reporter. Read an insightful article by Monika Opalek, PhD: https://lnkd.in/dX3pcnvE #Pharmacogenomics #PersonalizedMedicine #Genetics #ClinicalPractice #Intelliseq

Our team had an amazing experience at the BioMeeting 2024 conference this past weekend! Organized by Polish Bioinformatics Society event brought together leading minds in biotechnology to discuss groundbreaking advancements and research in genomics. We are incredibly grateful to all the attendees who showed great interest in our posters: 🔍 Application of long-read sequencing to improve genotyping of complex pharmacogenetic regions 🔍 Development of WGS pipelines for computation and reporting of polygenic risk scores A huge thank you to our dedicated team members Maria Paleczny, Mateusz Marynowski, and to Klaudia Szklarczyk-Smolana, for her insightful presentation on the iFlow platform. Special thanks to the Polish Bioinformatics Society for organizing such a fantastic conference. We appreciate the engaging discussions and valuable feedback. Looking forward to future opportunities to share our work and collaborate with such a vibrant community! #BioMeeting2024 #Genomics #Pharmacogenetics #PolygenicRiskScores #iFlowPlatform #PolishBioinformaticsSociety

Blood cancers, which include leukemia, lymphoma, and myeloma, account for approximately 10% of all new cancer diagnoses each year. Advances in medical treatments and early diagnostics have significantly improved survival rates. For instance, the five-year survival rate for leukemia has increased from 34% in the 1970s to over 60% today. At Intelliseq we know that in the fight against blood cancer, innovative solutions for early detection are paramount. That's why we have developed GeneSpect Myeloid Reporter, an automatic bioinformatic pipeline for the analysis and interpretation of next-generation sequencing (NGS) data for blood cancer patients. GeneSpect Myeloid Reporter, driven by iFlow Platform, provides a rapid, comprehensive analysis of NGS data, allowing healthcare professionals to make timely decisions that are critical for effective treatment. By utilizing the detailed molecular profile of a patient's tumor, our workflow can suggest the most effective and personalized therapy options, predict risk categories and support final diagnosis. In a form of a comprehensive report,  GeneSpect Myeloid Reporter provides information about the latest scientific research and clinical guidelines, offering healthcare professionals a clear and actionable understanding of each patient’s condition. By leveraging the power of genomic data, we are helping to transform the landscape of blood cancer treatment, one patient at a time. #WorldBloodCancerDay #WBCD

On May 23, we had the privilege of joining industry leaders and experts to discuss the future of genomics in Poland and Europe. It was an inspiring event focused on paving the way for our country's involvement in European genomic initiatives like +1MG. A big thank you to the organizers for hosting this incredible event. We are thrilled to have attended the inaugural Polish Genomics Day organized by Łukasiewicz - PORT The main topics covered during the event included: ✅ The current technological status and future directions of genomics and related fields such as biobanking in the EU and Poland. ✅ EU programs and genomic policy in Europe. ✅ The development of genomics in Poland over the coming years. ✅ Collaboratively creating a 10-year roadmap for genomics in Poland. We are excited about these initiatives and look forward to contributing to the advancement of genomics in our country and Europe. The collaboration and knowledge shared at this event are crucial steps towards a brighter future in the field of genomics. #Genomics #PolishGenomicsDay #Innovation #Intelliseq

Get to know Marcin Piechota, CTO and Co-Founder of Intelliseq, as he shares insights into the unique advantages of our innovative workflow technology that set us apart in the field of genetic data analysis and interpretation. Watch the full video: https://lnkd.in/dgQFDc59 #Genomics #HealthcareInnovation #PersonalizedMedicine #Intelliseq

If you're a bioinformatics geek (like some of our team members 😉), you might enjoy this recommendation! The Bioinformatics Chat is a podcast focused on bioinformatics, computational biology, and NGS. The topics are very broad, covering tools and models, research and analysis approaches, and biological implications. There are over 60 episodes so far, surely you'll find something that catches your interest!  🤖 🖥️  We hope you enjoy it! We're very curious to see which episode you start with - share your thoughts in the comments! 🙃 🙂 https://lnkd.in/dKVXPYFQ