Chan Zuckerberg Initiative

“Over the next 20 years, we’re going to see profound changes in how we do science.” CZI’s Head of Science Stephen Quake, D.Phil. shares our vision for using AI to help researchers make discoveries about human biology. We’re building AI tools to uncover new insights about how our cells function to identify and treat disease earlier. #science #AI #biomedicine #tech #SingleCell

Understanding the root causes of diseases is crucial, especially when it comes to unexplained conditions in children. Joe DeRisi is helping unravel these medical mysteries through groundbreaking research and technology as president of the Chan Zuckerberg Biohub San Francisco. When pediatric ICU doctor Aaron Bodansky of UCSF encountered children with severe multi-organ inflammation after mild COVID-19 infections, he reached out to Joe. With the help of PhIPseq technology, they discovered that the condition, known as MIS-C, was caused by molecular mimicry. The children’s immune systems mistakenly attacked their own cells, confusing them for COVID-19. This breakthrough not only unraveled the mystery of MIS-C but also showcased the potential of innovative, collaborative research in understanding human diseases. They have now profiled nearly 40,000 individuals across various autoimmune diseases, providing a rich data landscape for AI and machine learning to uncover new insights. “It's a really exciting time. We've spent years sequencing RNA, but now we're exploring the dynamic immune system and what it can do. This new frontier promises numerous discoveries and collaborations.” #MedicalResearch #COVID19 #PediatricCare #AI #AutoimmuneDisease #InnovationInScience

When we said “show us your excitement for AI in science” this group did not disappoint. Our AI in Single-Cell Biology Workshop brought together experts to explore how AI can revolutionize our understanding of cellular systems, leading to advancements in disease treatment and personalized medicine. This dynamic exchange of ideas from diverse perspectives and expertise sparked innovation and laid the groundwork for future developments at the intersection of AI and single-cell biology. By harnessing AI's power, researchers are decoding cellular complexity and paving the way for groundbreaking discoveries in human health. #AI #SciTech #science #innovation #TeamCZI

Our dream dinner guests? Synthetic biology experts 🤓 This week we hosted 30 at our headquarters to discuss the current state of synthetic biology. From the future of DNA synthesis to exploring the role of AI in gene prediction, we tackled some big challenges. Together, we're working to bridge knowledge gaps and accelerate advancements in this emerging field. #CellBiology #Science #AI #MachineLearning #SyntheticBiology

We love open science! One of many reasons is because we know software that is open source is key for making scientific discoveries that will one day cure, prevent and manage disease. As the largest funder committed to supporting critical open source software for science and 6 funding cycles under our belts, we set out to evaluate what the community needs for sustainability, and the successes funding has already led to. Join us in celebrating the open science community. #Science #OpenSource #Software #SciTech #ComputationalBiology

Teachers and school leaders know their kids best—and know what works in the classroom. This week, Our CEO Priscilla Chan and Common joined together to discuss how in order to build an education system that truly supports all students, we’ve got to have educators' expertise in the conversation. We’re excited to bring together educators, researchers and technologists to develop tools to help unlock student potential through Render—our edtech innovation studio. Learn more about this work: https://lnkd.in/gQ8X5vBp

Join us in welcoming our summer interns! We look forward to collaborating with them to build a more inclusive, just and healthy future for everyone. Can’t wait to see where the journey takes us! #TeamCZI #Interns #CZinterns #SummerInternship

🔉CZ Biohub Chicago is thrilled to announce its first cohort of Investigators, 48 innovative scientists and engineers hailing from our three partner universities, Northwestern University, University of Illinois Urbana-Champaign, and University of Chicago. This funding will enable Investigators to perform high-risk, high-reward research on topics related to instrumented tissues, inflammation, and the functions of the immune system. Meet the inaugural class of #CZBiohubCHI Investigators! University of Illinois Urbana-Champaign Indrani Bagchi, Ph.D., Rohit Bhargava, Ph.D, Qian Chen, Ph.D., Martha Gillette, Ph.D., Bumsoo Han, Ph.D., Amy Wagoner Johnson, Ph.D., Auinash Kalsotra, Ph.D., Hyunjoon Kong, Ph.D., Catherine Murphy, Ph.D.,  M. Taher Saif, Ph.D., Mei Shen, Ph.D.,  Shannon Sirk, Ph.D.,  Bradley Sutton, Ph.D., Jonathan Sweedler, Ph.D.,  Yurii Vlasov, Ph.D., Ayelet Ziv-Gal, Ph.D.   Northwestern University Navdeep Chandel, Ph.D., Jaehyuk Choi, M.D., Ph.D., Lee Cooper, Ph.D., Igor Efimov, Ph.D., Horacio Espinosa, Ph.D., Dominic Fullenkamp, M.D., Ph.D., Yogesh Goyal, Ph.D., Neil Kelleher, Ph.D., John Kessler, M.D., Huiping Lee, M.D., Ph.D., Chad Mirkin, Ph.D., Elizabeth McNally, M.D, Ph.D., Chian-Yu Peng, Ph.D.,  Arthur Prindle, Ph.D.,  Ali Shilatifard, Ph.D.,  Lisa Volpatti, Ph.D. University of Chicago Luis Barreiro, Ph.D., Marcus Clark, M.D., Ph.D., Bryan Dickinson, Ph.D.,  Aaron Esser-Kahn, Ph.D., Margaret Gardel, Ph.D., Aly Khan, Ph.D., Yang Li, Ph.D., Peter Mauer, Ph.D., Alex Pearson, M.D., Ph.D., Samantha Riesenfeld, Ph.D., Benjamin Shogan, M.D., Allison Squires, Ph.D., Melody Swartz, Ph.D.,  Savas Tay, Ph.D., Vincenzo Vitelli, Ph.D., Sihong Wang, Ph.D.

Celebrating our teammates at HQ week and our summer picnic was so fun!  From brainstorming new ideas to sharing laughs, it was a week to remember. It was wonderful to build community across the organization, learn, collaborate and celebrate the progress we’ve made in science, education and in the Bay Area. #TeamCZI #science #education #BayArea

Join us in celebrating Disability Pride Month! Our resource group for CZIers with disabilities and their allies chose Everyone, Everywhere as our theme because it reinforces how accessibility is important to everyone, everywhere, including those with visible and invisible disabilities. They are hosting activities in July to celebrate diversity, promote understanding and awareness, recognize achievements, challenge stigma, and work towards a more inclusive and equitable world for all. #DEI #InclusionMatters #DisabilityAwareness #DisabilityInclusion #TeamCZI