Javelin Biotech

⛳ Javelin Biotech Team Outing ⛳ Mini-golf, bumper boats, zip-lines, batting cages, and ice cream at Kimball Farm to celebrate 5 years of Javelin Biotech! It was such a fantastic day filled with laughter, camaraderie, and great memories. We are fortunate to have such an outstanding team, and we deeply appreciate the role each individual plays in making it so exceptional. Cheers to the Javelin team!

Looking forward to seeing our DMPK friends and colleagues next week at the Drug Metabolism Gordon Research Conference! Shiny Amala Priya Rajan, Ph.D., MBA will be presenting on “Closing the Translational Gap in Drug Development: Human Multi-Tissue Chip for Predictive and Mechanistic Preclinical Studies”. We hope to see you there! #livertissuechip #drugdiscoveryhumanized Gordon Research Conferences

This week, Javelin Biotech was showcased at the Massachusetts State House for an animal-free technology demonstration day held by The Humane Society of the United States in support of Bill H.850. This bill, sponsored by Rep. Jack Patrick Lewis, aims to reduce animal testing in cosmetics and household product development, promoting a more humane approach to scientific research. Murat Cirit and Kevin O'Handley demonstrated the Liver Tissue Chip platform and shared how we are humanizing research and product testing. Learn more about bill H850: https://lnkd.in/etayFyz7

Reflecting on an inspiring experience at the 2024 MPS World Summit: What a fantastic opportunity to connect with industry leaders and pioneers in the field of #microphysiologicalsystems and #organsonchips. The exchange of ideas and expertise was truly enriching, and we're excited about the possibilities that lie ahead. Thank you to everyone who visited our booth and engaged with us during the conference. Let's keep the conversation going! Feel free to reach out for more information on our tissue chip platform or to explore potential collaborations. Together, we can take steps to humanize drug discovery. email info@javelinbio.com to connect #MPSWorldSummit #livertissuechip #drugdiscoveryhumanized Murat Cirit Shiny Amala Priya Rajan, Ph.D., MBA James Ferritto Kevin O'Handley

Accurate clinical translation of preclinical research remains challenging, primarily due to species-specific differences and disease and patient heterogeneity. Given this, how do you know how relevant your model is? This study by Javelin Biotech describes the development of pathway-based similarity measurement (PBSM), which leverages RNA-seq data and pathway-based information to assess the human relevance of preclinical models for specific CoU. This figure shows PBSM-based scores for pre-clinical animal models of nonalcoholic fatty liver disease compared to reference human NAFL liver tissue samples for the KEGG NAFL pathway. There is a room for improvement - Stay tuned for more about Javelin’s human healthy and disease models! bioRxiv preprint: https://lnkd.in/dUZVAGCD

Are you at #MPSWorldSummit this week? Stop by Javelin's presentation, poster, or booth to chat about how we're humanizing drug discovery with the Javelin Tissue Chip Platform! If you would like to set up a meeting, send us a message or email info@javelinbio.com. We hope to see you! #livertissuechip #drugdiscoveryhumanized #organonchip #mpsworldsummit2024 #MicrophysiologicalSystems

Celebrating FIVE years of excellence, innovation, and teamwork at Javelin Biotech. A huge thank you to our team, clients, and partners who make it all possible. We’re grateful for the journey and excited for the future!

Our team is gearing up for the 2024 MPS World Summit from 6/10-14. Our Sr. Director of Product, Shiny Amala Priya Rajan, Ph.D., MBA, will be presenting a poster on “Closing the Translational Gap in Drug Development: Humanized Multi-Tissue Chip for Enhanced Pharmacokinetic and Toxicological Profiling" Wednesday June 12th from 10am-11:30am. Stop by poster #412 to chat with Shiny and learn more about how we’re humanizing drug discovery. If you would like to set up a meeting, send us a message or email info@javelinbio.com. We look forward to meeting you! #livertissuechip #drugdiscoveryhumanized #organonchip #mpsworldsummit2024 #MicrophysiologicalSystems

Heading to the MPS World Summit? Interested in how to qualify MPS for a defined context of use and applicability domain? Don't miss Murat Cirit's talk on “Pathway-based Similarity Measurement (PBSM) of Preclinical Models and Clinical Tissue Samples to Define Context of Use (CoU) Applications” in Session 3.1 on Tuesday 6/11 at 11:30am. If you would like to set up a meeting, send us a message or email info@javelinbio.com. We look forward to meeting you! #drugdiscoveryhumanized #organonchip #mpsworldsummit2024 #MicrophysiologicalSystems

Javelin is excited to announce that we will be exhibiting at the upcoming MPS World Summit conference in Seattle from June 10-14th. Make sure to visit us at booth 13 to see our Liver Tissue Chip Platform and learn how we’re humanizing drug discovery. If you would like to set up a meeting, send us a message or email info@javelinbio.com. We look forward to meeting you! #livertissuechip #drugdiscoveryhumanized #organonchip #mpsworldsummit2024 #MicrophysiologicalSystems