Quantum-Si

The Quantum-Si team is on our way to the HUPO World Congress 2024 in Dresden! We’re excited to join the global #proteomics community and showcase our latest advancements in Next-Generation Protein Sequencing™. If you’re attending, be sure to check out Gloria Sheynkman’s poster presentation, "Next-Generation Protein Sequencing Resolves Peptide Variants Derived From Tropomyosin Proteoforms" where she’ll dive into groundbreaking proteoform analysis. We can’t wait to connect with you in Dresden and share how our technology is pushing the boundaries of proteomics! #HUPO2024 #Proteomics #NextGenProteinSequencing #QuantumSi #ProteoformAnalysis

Proud to be recognized by The Medicine Maker as a company shaping the future of drug discovery. Thanks to our own Meredith L. Carpenter, PhD for capturing the potential for us! https://lnkd.in/gRAb9vAa

Curious about how the latest tech is transforming protein analysis? Buckle up! In this exciting webinar, Dr. Michael Caldwell from the Northwestern Proteomics Center of Excellence dives deep into the cutting-edge world of top-down mass spectrometry (TD-MS) and Quantum-Si’s Platinum® system, the ultimate duo for precision protein sequencing. If you’re a scientist eager to tackle the intricate challenges of proteoform analysis, this is one webinar you don’t want to miss! Why Does It Matter? Protein variation is a tricky puzzle—it's influenced by everything from biological factors to how samples are prepared and the settings on your instruments. Traditional methods often fall short when it comes to revealing the full complexity of proteoforms. That’s where next-generation tools come in, bringing the precision you need to unlock new insights. Meet Platinum®: Your New Lab Sidekick So, what’s Platinum all about? It’s a powerful benchtop instrument designed to analyze single protein molecules with single amino acid resolution. Imagine being able to decipher the exact sequence of amino acids, one by one, revealing every twist and turn—including tricky post-translational modifications like pyroglutamate (pE). Whether you’re studying proteins like IL-6 or diving into other complex structures, Platinum gives you the complete picture, from top to bottom! The Dynamic Duo: TD-MS + Platinum® Together, TD-MS and Platinum create a dream team for protein analysis. Here’s the magic: TD-MS captures intact proteins in their natural form, minimizing those pesky modifications that can skew results during initial analysis (MS1). Then, in MS2, TD-MS digs deeper, analyzing fragmented ions to reveal hidden modifications or artifacts that could be missed by other techniques. Platinum® takes it a step further! It uses dye-labeled recognizers to identify each amino acid, then deploys aminopeptidases to expose the next one—continuing until the full peptide is mapped out, like a molecular jigsaw puzzle. With this approach, you get unmatched insight into protein structure, spotting both functionally crucial regions and those prone to modifications like pE formation. What’s In It for You? Discover how TD-MS and Platinum® work hand in hand to offer a comprehensive, in-depth view of proteins. Learn the secrets to seamlessly connecting discovery-based research with targeted protein analysis. Gain a new perspective on differentiating between native proteoforms and those altered by experimental conditions. Get ready to level up your protein analysis game! Join us for a journey through the future of proteomics and see how Quantum-Si’s Platinum® can bring precision, clarity, and depth to your research. DMark Biosciences, #Proteomics, #ProteinSequencing, #Genomics See the link in the comments.

Talking protein sequencing at the Apella Center in RTP today 11 - 1:30.

We are looking forward to being part of the 23rd Human Proteome Organization (HUPO) World Congress on October 20-24,2024 in Dresden, Germany. Our team will be on hand to showcase Next-Generation Protein Sequencing™ technology and detail WHY you should be using #Platinum® for deep characterization of your proteins. #HUPO #NGPS Contact us here to secure time with our team! https://lnkd.in/e6hVNEdm

We are seeking an experienced Sr. Principal #SystemsEngineer to lead the development of Next-Gen Protein Sequencing™ systems and manage a team of engineers. This is a critical leadership role driving innovation at the intersection of engineering and life sciences. Consider joining us to shape the future of #proteomics! Apply here: https://lnkd.in/eVd3zR-V #QSI #NGPS #Innovation #Engineering #Careers #Job

I am very pleased to announce that I will be presenting about the Platinum® Next-Generation Protein Sequencing(TM) platform from Quantum-Si at the upcoming Omics by Oxford Global event, NextGen Omics in London. Join me for the presentation on Wednesday, 23rd October at 10.20 in conference room 2. Additionally, visit our booth (#49) at the exhibition where Paru Oatey, Barry Ewen, Matthew Wright, and I will be available to discuss the technology and its applications. #proteomics #multiomics #proteogenomics #NGPS #proteoforms #protein #sequencing #qsi

Did you miss Michael Caldwell, PhD’s deep dive into proteoform analysis? No worries—his webinar, "Integrating Top-Down #MassSpectrometry and Single-Molecule Sequencing for Proteoform Analysis," is now available on-demand. Dr. Caldwell explains how top-down mass spectrometry (TD-MS) and Quantum-Si’s Platinum® instrument work together to analyze proteins with incredible precision. Why watch it? -Understand how TD-MS and Next-Generation Protein Sequencing™ complement each other for comprehensive protein analysis.      -Explore ways to bridge discovery and targeted protein analysis across different platforms.    -Learn to distinguish between native and artifactual proteoforms. Catch the webinar on-demand and take your research to the next level. https://lnkd.in/eBmVEBHg #proteinsequencing #NGPS #QSI #Proteomics

Exciting news! We’re thrilled to announce that Quantum-Si will be showcasing our latest breakthroughs in proteomic research at the #HUPO World Congress 2024 in Dresden, Germany. As pioneers of Next-Generation Protein Sequencing™ (NGPS), our team is excited to share new data from Platinum®, the first NGPS instrument available on the market. John Kudolo will discuss how #QSI's Next-Generation Protein Sequencer™ enables protein detection and peptide characterization, and Gloria Sheynkman from the University of Virginia will highlight the sequencing of proteoform-specific peptides using tropomyosin as a model system. Additionally, on Tuesday, October 22, Meredith L. Carpenter, PhD Carpenter from QSI and Neil Kelleher from Northwestern University will lead a breakfast talk on enhancing proteoform analysis through the combination of NGPS and top-down mass spectrometry. Check out the full press release here: https://lnkd.in/ey9bc3qp #Proteomics #NGPS #HUPO2024 #QuantumSi #ProteinSequencing #Biotech #ScientificInnovation #Platinum Jeff Hawkins