Two Sigma Ventures

Scent teleportation is here. Games now build themselves in real time as you play. Menopause treatment gets funding to target the source, not symptoms. Osmo teleported scent across their lab & taught computers to smell - first ever working digital olfactory system that can capture & recreate any scent. Plus, their public beta just dropped: imagine any scent in natural language, they'll bring it to life in their lab & send it to you. Etched's Oasis just launched the first fully AI-powered game - generating & running entire playable worlds in real-time, creating new environments as you move. Gameto secured $10M from ARPA-H to advance their menopause program Ameno - moving beyond symptom treatment to address root causes and help women maintain quality of life long-term. TSV portfolio absolutely sprinting into the future over the past week 🔥

In case you missed it… 👀 We’ve launched Remote Equity! 🎉 In partnership with Carta, we’re making global equity compensation easier than ever. Now, companies can grant stock options to direct & EoR employees and contractors across 75+ countries. Catch all the details on TechCrunch👇 https://tcrn.ch/3YFiXwo

Well, we actually did it. We digitized scent. A fresh summer plum was the first fruit and scent to be fully digitized and reprinted with no human intervention. It smells great. Holy moly, I’m still processing the magnitude of what we’ve done. And yet, it feels like as we cross this finish line we are instantly at a new starting line. I’ll have more to share about what’s in store that we’re building on top of this. A huge HUGE congrats to the entire team across scientific, engineering, operational, and creative disciplines. It takes a village named Osmo to do this. I don’t know if this is embarrassing, but I carry the plum scent with me a lot of places and smell it constantly. It makes me smile. I’m curious, if y’all want to smell it? If we made a limited release fragrance of the first teleported scent and dedicated the proceeds to science, would you buy it?

"With six people, we built, from scratch, the fastest laser melting platform on the planet... We did things people said you couldn't do." - Erik Palitsch, Freeform CEO / Co-Founder Since meeting the Freeform team, we've been blown away by their ability to execute - combining AI, supercomputing, and advanced sensing to completely reimagine metal 3D printing. Their momentum continues with today's exciting news –– a $14M raise from NVIDIA and Boeing! They're hiring across engineering and operations - check them out if you want to help shape the future of manufacturing + read the full TechCrunch article below.

Major congrats to TSV portfolio company Terray Therapeutics on their $120M Series B funding round led by Bedford Ridge Capital and nVentures! From Endpoints News: "Terray has generated its own proprietary dataset of protein-molecule interactions 50 times larger than publicly available data. The biotech has used that data to train AI models to discover and design small molecules in a new way for a biopharma company, placing the AI's ideas at the center of its R&D process." We got to see the cornerstone of Terray's data generation process - a chip the size of a nickel - when co-founders Jacob Berlin, PhD and Eli Berlin joined TSV and Dusan Perovic last month to share their vision for the future of drug discovery. For more details on Terray's innovative approach and recent funding, check out the full Endpoints News article below.

🚨 Announcing our latest investment: Arda Therapeutics! Arda is developing a novel approach to chronic disease treatment, starting with fibrosis. Their cell-depleting technology aims to eliminate specific disease-driving cells, rather than just modifying cell behavior. By combining advanced data science with cellular biology, Arda is working to address chronic diseases at their source. Link to Dusan Perovic & Elianna (Elizabeth) Knight's blog post on why we invested in Arda in the comments!

Recently, Gameto’s Co-founder and CEO, Dina Radenkovic (Turner) had the opportunity to present at the Two Sigma Ventures annual conference together with our investor and Board Director Dusan Perovic. They talked about the work that Gameto is doing in the women’s health space, specifically in fertility and menopause, and discussed some of the new data that our team will be presenting over the coming weeks. Thank you to Two Sigma for having us!

Arda is pleased to announce the closing of our $43M Series A financing to accelerate the development of precision cell-depleting biologics to treat chronic diseases. The new capital will be used to drive our existing I&I pipeline toward the clinic, expand into new indications, and scale our single cell discovery platform. Thank you to our investors Andreessen Horowitz, Two Sigma Ventures, RV Invest, Eli Lilly and Company, GV (Google Ventures), Biovision Ventures, Valhalla Ventures, Indicator Ventures, Alumni Ventures, LifeLink Ventures, Mana Ventures, Gaingels, and Exitfund. Learn more about our mission to deplete pathogenic cells to treat disease at www.ardatx.com!

I have news to share - we raised our Series A! It was led by Frances Schwiep and the Two Sigma Ventures team with participation from Andreessen Horowitz Operator Collective 🔆 Oregon Venture Fund Alumni Ventures! Essence Venture Capital and a group of angel investors. We have a huge opportunity, a great team and a lot of momentum - and now have raised $30M within the first year of founding to tackle this important problem. I'm excited for this next phase. Giddy up! https://lnkd.in/gs9wDRSD

We're excited to announce that we’ve led Distributional's $19 million Series A! As AI adoption soars, so do the risks. Distributional is tackling this challenge head-on. They're building an advanced testing suite for enterprise AI applications, designed to bridge the AI Confidence Gap - the tension between innovation and risk in AI deployment. We believe Distributional is uniquely positioned to make enterprise AI not just powerful, but consistently reliable and trustworthy. Congrats to Scott Clark, Nick Payton, and the entire team! Learn why we’re backing Distributional: https://bit.ly/4eSbHTg