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From Rugby to Tennis, Football to Track & Field, Gymnastics to Swimming, athletes put their bodies through high levels of vigorous training and push them to the absolute limit. Now, typically I share posts about Biotech companies accelerating the research for new therapies for various diseases and illnesses and this will always remain my top interest when it comes to Biotech advancements. HOWEVER, when it comes to sports I always have a keen interest in knowing what's next? Whether its athletes using wearable devices to understand their performance or understanding the next steps in recovery, I will always try to understand what the next development is. Seeing articles like this really shines a light on technology and research can help athletes break records and make history, which for me is very exciting! #sportsperformance #biotech #geneticprofiling #athleticperformance #OlympicGames2024 #biotechinsports #AspireLifeSciences

🚀 The fusion of biotechnology and sports is transforming athletic performance! From personalized training programs based on genetic testing to cutting-edge injury prevention and recovery methods, athletes are achieving new heights. 🏋️♂️🧬 Discover how innovations like gene editing, regenerative medicine, and wearable tech are redefining the limits of human potential in sports. 🌟 Check out this insightful article to learn more about the groundbreaking ways biotech is revolutionizing sports performance: Read more here: https://lnkd.in/e-x4grnN #Biotechnology #SportsPerformance #Innovation #AthleteHealth #GeneticTesting #WearableTech

#Nanotechnology - Recent advancements in the #medical field, particularly in #cancer treatment, #drug delivery, and #vaccine development. 👉Cancer Treatment - Researchers have developed nanorobots that can target and kill cancer cells more efficiently. One notable study demonstrated the use of a DNA-based nanorobot with a hidden weapon designed to seek out and destroy cancer cells in mice. This nanorobot can be further refined to increase its targeting accuracy by incorporating specific proteins or peptides on its surface, allowing it to bind to particular cancer types. (ScienceDaily) (Phys.org) 👉Nanoparticle-Based Vaccines - At MIT, scientists are exploring the use of metal-organic frameworks to enhance vaccine efficacy. In their studies on mice, they found that MOFs could encapsulate parts of the SARS-CoV-2 spike protein and act as an adjuvant to stimulate a robust immune response. This technology not only promises to improve the effectiveness of vaccines but also offers a potentially cheaper and easier-to-manufacture alternative to current mRNA vaccines, which could enhance global vaccine accessibility (MIT News). 👉Precision Medicine and Drug Delivery - Nanoparticle-based delivery systems are revolutionizing precision medicine. These systems can encapsulate drugs and deliver them directly to specific cells or tissues, minimizing side effects and increasing treatment efficacy. For instance, researchers have developed a microrobot-packed pill that shows promise for treating inflammatory bowel disease by delivering medication directly to the inflamed areas in the gastrointestinal tract. (ScienceDaily) 👉Computational Nanotechnology and Green Nanotechnology - Computational nanotechnology is enhancing the development of intelligent nanoparticles, which can be used in various applications, including drug delivery and environmental monitoring. Additionally, green nanotechnology practices are becoming more prevalent, focusing on sustainable nanoparticle synthesis methods and the use of biodegradable materials. These practices help reduce the environmental impact of nanotechnology while maintaining its benefits. (StartUs Insights) 👉Wearable Health Monitors - Innovations in nanotechnology are also advancing wearable health monitors. A recent development includes a wearable ultrasound patch that allows continuous, non-invasive monitoring of cerebral blood flow. This technology has significant implications for monitoring and managing conditions such as stroke and other cerebrovascular diseases. (ScienceDaily) #healthcare #innovation #technology #nantechnology #nanoparticle #materialscience #nanomaterials #nanorobotics #wearabletech #science #research

**DID YOU KNOW** Did you know that by introducing more stem cells into the body, you can experience a higher rate of healing and regeneration? More stem cells in the blood means that those cells will differentiate into several types of cells needed for repair - lung cells, skin cells, heart tissue, muscle issue, bone and even connective tissue. This is exactly what our company has done with their patented technology with the NATURAL stem cell activation PATCH that’s turns your Dormant Stem Cells back on. Through the process called Photo-Bio-Modulation, this wafer thin wearable patch causes your body to activate your dormant stem cells and it floods your body with young stem cells. The result is an unparalleled level of health and vitality. This is futuristic technology at its best! SEE THE DIFFERENCE, TAKE THE JOURNEY!

Nanomaterial with potential to tackle multiple global challenges could be developed without risk to human health. A revolutionary nanomaterial with huge potential to tackle multiple global challenges could be developed further without acute risk to human health, research suggests. The study is published in the journal Nature Nanotechnology. Carefully controlled inhalation of a specific type of graphene—the world's thinnest, super strong and super flexible material—has no short-term adverse effects on lung or cardiovascular function, the study shows. The first controlled exposure clinical trial in people was carried out using thin, ultra-pure graphene oxide—a water-compatible form of the material. Researchers from the The University of Edinburgh and The University of Manchester recruited 14 volunteers to take part in the study under carefully controlled exposure and clinical monitoring conditions. The volunteers breathed the material through a face mask for two hours while cycling in a purpose-designed mobile exposure chamber brought to Edinburgh from the National Public Health Institute in the Netherlands. Effects on lung function, blood pressure, blood clotting and inflammation in the blood were measured—before the exposure and at two-hour intervals. A few weeks later, the volunteers were asked to return to the clinic for repeated controlled exposures to a different size of graphene oxide, or clean air for comparison. There were no adverse effects on lung function, blood pressure or the majority of other biological parameters tested. Researchers noticed a slight suggestion that inhalation of the material could influence the way the blood clots, but they stress that this effect was very small. Dr. Mark R. Miller of the The University of Edinburgh's Centre for Cardiovascular Science, said, "Nanomaterials such as graphene hold such great promise, but we must ensure they are manufactured in a way that is safe before they can be used more widely in our lives. ...Professor Kostas Kostarelos, of the The University of Manchester and the Catalan Institut Català de Nanociència i Nanotecnologia (ICN2) in Barcelona, said, "This is the first-ever controlled study involving healthy people to demonstrate that very pure forms of graphene oxide—of a specific size distribution and surface character—can be further developed in a way that would minimize the risk to human health. ... Professor Bryan Williams OBE MD FMedSci, Chief Scientific and Medical Officer at the British Heart Foundation, added, "The discovery that this type of graphene can be developed safely, with minimal short term side effects, could open the door to the development of new devices, treatment innovations and monitoring techniques. We look forward to seeing larger studies over a longer timeframe to better understand how we can safely use nanomaterials like graphene to make leaps in delivering lifesaving drugs to patients." By The University of Edinburgh

Hello, Dear Connections, As someone interested in the biomedical engineering field, I am excited to share some advancements in nanotechnology that are transforming drug delivery systems. The convergence of nanotechnology and medicine is opening up new frontiers for more effective, targeted, and personalized treatments. Here’s how: 🔬 Precision Targeting Nanotechnology enables the development of drug delivery systems that can precisely target diseased cells, minimizing the impact on healthy tissues. This precision reduces side effects and increases the efficacy of treatments, particularly in cancer therapy. Nanoparticles can be engineered to recognize and bind to specific cell receptors, ensuring that the medication reaches its intended destination. 💡 Enhanced Drug Solubility and Bioavailability Many drugs suffer from poor solubility and bioavailability, limiting their effectiveness. Nanotechnology can enhance the solubility of drugs, allowing for better absorption and improved therapeutic outcomes. Nanocarriers, such as liposomes and polymeric nanoparticles, help in delivering hydrophobic drugs in a more soluble form. ⏳ Controlled and Sustained Release Nanotechnology allows for the design of drug delivery systems that provide controlled and sustained release of medication. This means that drugs can be released at a consistent rate over a prolonged period, reducing the need for frequent dosing and improving patient compliance. The controlled release also ensures a steady therapeutic effect, enhancing the overall treatment process. 🌐 Crossing Biological Barriers One of the significant challenges in drug delivery is crossing biological barriers, such as the blood-brain barrier. Nanoparticles have shown promise in overcoming these barriers, enabling the delivery of drugs to previously inaccessible areas of the body. This advancement opens up new possibilities for treating neurological disorders and brain cancers. 🔍 Future Prospects The future of nanotechnology in drug delivery is incredibly promising. Research is ongoing to develop smart nanoparticles that can respond to environmental stimuli, such as pH or temperature changes, for on-demand drug release. Additionally, integrating nanotechnology with other cutting-edge fields like gene therapy and immunotherapy holds the potential for creating highly personalized treatment regimens. Thank you for reading, and let’s keep pushing the boundaries of biomedical engineering! #BiomedicalEngineering #Nanotechnology #DrugDelivery #HealthcareInnovation #TargetedTherapy #ControlledRelease #FutureOfMedicine

**DID YOU KNOW** Did you know that by introducing more stem cells into the body, you can experience a higher rate of healing and regeneration?More stem cells in the blood means that those cells will differentiate into several types of cells needed for repair - lung cells, skin cells, heart tissue, muscle issue, bone and even connective tissue. This is exactly what our company has done with their patented technology with the NATURAL stem cell activation PATCH that’s turns your Dormant Stem Cells back on. Through the process called Photo-Bio-Modulation, this wafer thin wearable patch causes your body to activate your dormant stem cells and it floods your body with young stem cells. The result is an unparalleled level of health and vitality. This is futuristic technology at its best! SEE THE DIFFERENCE, TAKE THE JOURNEY! www.RegenLifePatch.com

Long-Sought CaE2P State Captured: Cryo-EM Illuminates SPCA1's Transport Cycle Secretory-pathway Ca2+-ATPases (SPCAs) are nature's tiny gatekeepers, controlling the flow of calcium ions within cells. These critical molecules ensure proper calcium concentrations, vital for diverse functions like cell signaling, muscle contraction, and protein processing. Understanding how SPCAs work, particularly human SPCA1 (hSPCA1), has remained a scientific puzzle. This research unveils a groundbreaking feat—capturing six snapshots of hSPCA1 in action, using an advanced technique called cryo-electron microscopy (cryo-EM). These snapshots, like frames in a movie, reveal the protein's intricate dance during calcium transport. From Fueling to Release Imagine hSPCA1 as a molecular pump, powered by the energy molecule ATP. The journey unfolds in these key stages: • Calcium Entry: Calcium ions bind to a specific pocket on hSPCA1, ready to be transported. • Fueling Up: ATP binds to the pump, injecting energy into the system. • Phosphorylation Boost: A phosphate group attaches to the pump, triggering conformational changes. • The Twist: An intriguing twist occurs—transmembrane helices shift, squeezing the calcium pocket and pushing the ions toward the other side of the membrane. • Release and Reset: Calcium ions are released into the target compartment, and the pump resets for another round. Unprecedented Moves What's remarkable is that hSPCA1's dance differs from other pumps. Its ATP binding and phosphorylation steps involve unique movements, highlighting the protein's specialized function. Additionally, the helix twist creates a powerful squeeze, a previously unseen mechanism for calcium release. The Missing Piece Found Moreover, this research captures the elusive CaE2P state, a crucial but rarely observed stage in the cycle. This missing piece adds clarity to the entire pumping process. Beyond the Lab Understanding hSPCA1's intricate work has exciting implications beyond basic science. Mutations in this protein are linked to Hailey-Hailey disease, a skin disorder. Deciphering its function paves the way for designing potential therapies and improving diagnosis. Furthermore, insights into SPCA1's unique pumping mechanism could inspire the development of novel biomimetic pumps for nanotechnology and drug delivery applications. In conclusion, this groundbreaking research unveils the hidden choreography of hSPCA1's calcium transport, offering a deeper understanding of cellular processes and opening doors for future innovations in healthcare and beyond. 📝 Article, Open Access https://lnkd.in/e6Cge2j9 📷 EM Map Analysis https://lnkd.in/eQTaWbij 📎 Free Use and License https://lnkd.in/gpbw3cEg 📌 About EM Data Bank https://lnkd.in/ePU9n4kv Wu M, Wu C, Song T, Pan K, Wang Y, Liu Z. Cell Res (2023) #disease #research #structuralbiology #merize

#goldnanoparticles #colloidalgold #lateralflow The Fascinating Science Behind Gold Particles in Biomedical Applications Gold, a precious metal long prized for its beauty and durability, is undergoing a remarkable transformation in the world of medicine. Forget crowns and jewelry – scientists are now harnessing the unique properties of gold particles at the nanoscale (incredibly tiny, measured in billionths of a meter) to develop innovative biomedical applications. But what makes gold so special in this new realm? The key lies in its interaction with light. When light hits gold nanoparticles, it excites the metal's electrons, causing a collective oscillation known as surface plasmon resonance. This fancy term translates to some pretty cool abilities: Heat Generation: Gold nanoparticles can convert light energy into heat very efficiently. This property has applications in cancer treatment, where gold particles can be directed to tumors and then irradiated with lasers. The heat generated by the particles destroys cancer cells while leaving healthy tissues relatively unharmed. Light Scattering: Gold nanoparticles can scatter light with specific colors depending on their size and shape. This makes them ideal for creating contrast agents in medical imaging techniques like photothermal imaging and computed tomography (CT scans). By attaching these gold particles to molecules of interest, such as antibodies targeting specific diseases, doctors can gain a clearer picture of what's happening inside the body. Drug Delivery: Gold nanoparticles can be used as carriers for drugs. They can be designed to bind to specific molecules, allowing them to deliver their cargo directly to diseased cells and avoid healthy tissues. This targeted approach has the potential to reduce side effects and improve treatment efficacy. The science behind gold nanoparticles in biomedicine is still evolving, but the potential is vast. Researchers are exploring their use in: Gene Therapy: Gold nanoparticles could be used to deliver genetic material into cells, potentially paving the way for new treatments for genetic diseases. Antibacterial Treatments: Certain types of gold nanoparticles exhibit antibacterial properties, offering a potential weapon in the fight against antibiotic-resistant bacteria. Diagnostics: Gold nanoparticles can be used to develop highly sensitive biosensors for detecting diseases at early stages. The journey from a prized metal to a cutting-edge medical tool is a fascinating example of scientific ingenuity. As research continues, gold nanoparticles have the potential to revolutionize healthcare, offering more precise and effective treatments for a wide range of diseases.

A revolutionary nanomaterial with huge potential to tackle multiple global challenges could be developed further without acute risk to human health, research suggests. Carefully controlled inhalation of a specific type of graphene – the world’s thinnest, super strong, and super flexible material – has no short-term adverse effects on lung or cardiovascular function, the study shows. The first controlled exposure clinical trial in people was carried out using thin, ultra-pure graphene oxide – a water-compatible form of the material. Researchers say further work is needed to find out whether higher doses of this graphene oxide material or other forms of graphene would have a different effect. The team is also keen to establish whether longer exposure to the material, which is thousands of times thinner than a human hair, would carry additional health risks. There has been a surge of interest in developing graphene – a material first isolated by scientists in 2004 and which has been hailed as a ‘wonder’ material. Possible applications include electronics, phone screens, clothing, paints, and water purification. Graphene is actively being explored around the world to assist with targeted therapeutics against cancer and other health conditions, and also in the form of implantable devices and sensors. Before medical use, however, all nanomaterials need to be tested for any potential adverse effects. #graphene #safety #inhalation #study #sensors #therapeutics #applications https://lnkd.in/ggc38SG7