Serac Life Sciences’ Post

We are excited to report that an abstract on preliminary data from our DETECT imaging study has been accepted as a Top Rated Oral Presentation at the annual congress of the European Association of Nuclear Medicine (EANM) taking place from 18-23 October 2024 in Hamburg, Germany. The DETECT study is evaluating the potential of maraciclatide to visualise endometriosis, and specifically superficial peritoneal endometriosis, which could have a significant impact on the lives of millions of women suffering with the disease. The study is ongoing and the presentation will include the latest findings and insights into the detection of disease subtypes. Many thanks to authors Munir Ghesani MD, FACNM, FACR, FSNMMI Jon Barnett Tatjana Gibbons Druin Burch; S Cade and R Graham (Royal United Hospitals Bath NHS Foundation Trust); N Patel (John Radcliffe Hospital, Oxford); Krina Zondervan and C Becker (Nuffield Dept of Women's & Reproductive Health, University of Oxford and EndoCaRe Oxford 🎗️ ). Maraciclatide is for investigational use only and is not approved by the FDA or UK and European regulatory authorities. #endometriosis #womenshealth #molecularimaging #diagnosticimaging #medicalimaging #precisionmedicine #nuclearmedicine

【#HotTrend： Scientists conduct world's first transplant of pig liver into human patient👨🏻⚕️】 According to Air Force Medical University, a research team successfully transplanted a gene-edited pig liver into a brain-dead patient to mimic the treatment of liver failure patients🩺. This is the world's first case of pig liver xenotransplantation, demonstrating the potential for gene-edited pig livers to replace human livers in the future. Source：https://bit.ly/4cvizFV  #HongKongLaureateForum #LeeShauKeeFoundation #Science #pigliver #humanpatient #firstcase #xenotransplantation

Management of cardiogenic shock, state-of-the-art: 🩺 definition of CS, pathophysiology, clinical & hemodynamic phenotypes 🌈 heterogeneity of CS clinical syndrome traditional approach: clinical/hemodynamic profiles current/emerging approach: SCAI shock severity staging future approach of CS: biological/biomarker-driven phenotypes diagnosis and laboratory evaluation hemodynamic monitoring contemporary outcomes causal treatment cardiac arrest resource use 💊 pharmacologic management of CS ⚙️ mechanical circulatory support devices 🔮 future directions Open access #FOAMcc 🔓 https://bit.ly/3XipcV3

New CE module - WB2568 Interpreting Pathophysiology through Electronic Fetal Monitoring. Compare and contrast use of physiological interpretation principles and the use of current fetal heart rate tracing classification systems to identify the fetus at risk, summarize the types of intrapartum fetal hypoxia and their features, and outline pathophysiological process and possible mechanisms for fetal heart rate abnormalities in the absence of fetal acidemia.

🫀 Management of cardiogenic shock: open access review providing comprehensive synthesis of contemporary literature regarding definition & classification, pathophysiology, workup, and (personalized) management, including use of temporary mechanical circulatory support #MCS (as #ECMO and microaxial flow pumps) according to latest evidence. Open access #FOAMcc #FOAMecmo 🔓 https://bit.ly/3XipcV3

Climate change poses significant challenges to health care, with radiation oncology being no exception. Educational gaps exist among radiation oncology professionals regarding the implications of climate change on patient care and health care delivery. This study aims to assess the perspectives of US and Canadian radiation oncology program directors (PDs) and associate program directors (APDs) on climate change education and its integration into residency programs. Read more ➡️ https://bit.ly/3U9YQV1

Rehabilitation interventions are complex and studying their effectiveness is methodologically challenging. In our new paper in the European Journal of Physical and Rehabilitation Medicine (part of a series from Cochrane Rehabilitation), we offer an alternative to the randomized control trial when it cannot be conducted. We discuss how the Target Trial Emulation framework can be used to study the effectiveness of rehabilitation interventions. https://lnkd.in/gvhVQkBr

“"What this drug does is it stops those pathways that calcium comes into the brain cells and just hibernates them. "Around 1.9 million brain cells are dying every second that blood flow is stopped and that's why the time frame for receiving a potentially life-saving treatment is so critical." The peptide molecule ARG-007 was developed in the state at the Perron Institute and the University of Western Australia.”- with stroke being one of the leading causes of death worldwide, it’s great to see such drug enter human trials! #strokerecovery #strokeresearch #brainresearch #clinicalresearch #clinicaltrials #insightful

For 30 years, Hytest has been at the forefront of cardiac troponin research, and we remain dedicated to scientific excellence in this field 🫀 🧑🔬 In our new study, we investigated the influence of heparin on the immunodetection of human cardiac troponins. 🔍 There is conflicting data regarding the effects of heparin on the measurement of cardiac isoforms of troponin I (cTnI) and troponin T (cTnT), which are used for the immunodiagnosis of acute myocardial infarction. 💡 The study concluded that heparin binds to the ITC-complex via cTnT, interacting with several sites on the N-terminal and/or central parts of the cTnT molecule, which might influence the immunodetection of analytes in human blood. Read more: https://lnkd.in/dycRf8xP #IVD #CardiacTroponin #heparin #AMI

Concurrent with the initiation of our Phase 2 study of CIN-103 for the treatment of chronic #IrritableBowelSyndrome with predominant diarrhea (IBS-D), Dr. Darren Brenner, Professor of #Gastroenterology at Northwestern University, shared his thoughts on CIN-103's potential to address the unmet medical need for a long-term treatment of IBS-D. Learn more: https://bit.ly/48ug4QW