Serac Healthcare’s Post

【#HotTrend： Scientists conduct world's first transplant of pig liver into human patient👨🏻⚕️】 According to Air Force Medical University, a research team successfully transplanted a gene-edited pig liver into a brain-dead patient to mimic the treatment of liver failure patients🩺. This is the world's first case of pig liver xenotransplantation, demonstrating the potential for gene-edited pig livers to replace human livers in the future. Source：https://bit.ly/4cvizFV  #HongKongLaureateForum #LeeShauKeeFoundation #Science #pigliver #humanpatient #firstcase #xenotransplantation

Delving into the intricacies of #transfusion #reactions , this webinar, originally presented on October 24, 2023, shines a spotlight on #hyperhemolysis, exploring clinical features, lab investigations, and management hurdles. We're privileged to have distinguished speakers like Dr. Christine Cserti-Gazdewich from Canada, alongside UK's own experts - Dr. Anicee Danaee, Dr. Joseph Sharif, and Tracey Tomlinson. Join this in uncovering valuable resources and essential published literature. A knowledge-sharing session you won't want to miss! #immunohematology_made_easy #TransfusionReactions #MedicalScience #WebinarInsights #Healthcare #Pathophysiology #ClinicalFeatures #MedicalResearch #ExpertSpeakers #KnowledgeSharing #October24 #HealthcareWebinar

New CE module - WB2568 Interpreting Pathophysiology through Electronic Fetal Monitoring. Compare and contrast use of physiological interpretation principles and the use of current fetal heart rate tracing classification systems to identify the fetus at risk, summarize the types of intrapartum fetal hypoxia and their features, and outline pathophysiological process and possible mechanisms for fetal heart rate abnormalities in the absence of fetal acidemia.

Rehabilitation interventions are complex and studying their effectiveness is methodologically challenging. In our new paper in the European Journal of Physical and Rehabilitation Medicine (part of a series from Cochrane Rehabilitation), we offer an alternative to the randomized control trial when it cannot be conducted. We discuss how the Target Trial Emulation framework can be used to study the effectiveness of rehabilitation interventions. https://lnkd.in/gvhVQkBr

Our study shows high B7–H3 expression suppressed the positive impact of HLA class I expression in PDAC survival and that their expression is co-regulated by p65 (RelA). These findings provide the rationale for B7-H3 immunotargeting to elicit T cell-mediated antitumor response in HLA class I positive PDAC. @MGHSurgery Harvard Medical School https://lnkd.in/g9QPCd9S

Concurrent with the initiation of our Phase 2 study of CIN-103 for the treatment of chronic #IrritableBowelSyndrome with predominant diarrhea (IBS-D), Dr. Darren Brenner, Professor of #Gastroenterology at Northwestern University, shared his thoughts on CIN-103's potential to address the unmet medical need for a long-term treatment of IBS-D. Learn more: https://bit.ly/48ug4QW

News Medical: Long COVID and ME/CFS patients could benefit from a coordinated treatment strategy People suffering from Long COVID or Myalgic Encephalomyelitis /Chronic Fatigue Syndrome (ME/CFS) could benefit from a coordinated treatment strategy, a new University of Otago study has found. The pilot study, published in Scientific Reports, a Nature journal, has confirmed what researchers have suspected for some time: the two conditions are closely related. Lead author Emeritus Professor Warren Tate says the research – the first comparative molecular study of the immune cell proteins of both conditions – “strongly affirms” the link between the two. https://lnkd.in/ekRF9WWu #pwME #MECFS #LongCovid

“"What this drug does is it stops those pathways that calcium comes into the brain cells and just hibernates them. "Around 1.9 million brain cells are dying every second that blood flow is stopped and that's why the time frame for receiving a potentially life-saving treatment is so critical." The peptide molecule ARG-007 was developed in the state at the Perron Institute and the University of Western Australia.”- with stroke being one of the leading causes of death worldwide, it’s great to see such drug enter human trials! #strokerecovery #strokeresearch #brainresearch #clinicalresearch #clinicaltrials #insightful

Forging the path to revolutionary drug development and medical breakthroughs! 🚀 Researchers at the National Institute of Standards and Technology (NIST) have developed a #HeartOnAChip system that attacks the limitations of traditional cardiovascular disease research head-on. This innovative microchannel is not just a part of a larger Organ-On-A-Chip network system but a beacon of hope in cardiovascular disease research. Designed to mimic the human heart, it allows experts to manipulate and study the behaviour of cells under controlled conditions, leading to more accurate results. Let's applaud Derrick B. and Darwin Reyes for their remarkable achievement! 👏 Read more about this impressive research here:  https://lnkd.in/dEZiX52F. #MedicalResearch #OrganOnAChip #LabOnAChip #MicroFluidics #Nanostructure #NanoBioTechnology #NanoimprintLithography #UVNIL

Exciting work! Researchers have identified that alterations in AKT2 disrupt lysosome function in the retina, leading to drusen deposits, a hallmark of dry AMD (non-neovascular). This dysfunction, observed in both patient iPSC-derived RPE cells and mice models, results in RPE degeneration and drusen formation. ***The findings suggest that targeting the AKT2/SIRT5/TFEB pathway could be a potential therapy for dry AMD, a major cause of vision loss in the United States***. Worth reading: https://lnkd.in/ejdh4PUs