Winfried Neuhaus’ Post

Merci Yvon. Lemaho Aurélie Tasiemski Fabrice Bertile et Philippe BULET pour ce super article ! #Océan #Biomimétisme #Biomolécule #Biodiversité #Santé "As indicated by the participants of the 2019 #Nobel conference on Bioinspired Medicine in #Stockholm, the main limitation in all countries to investigate wild animals is poor academic funding. Most of the members of academic committees reviewing and selecting grant applications usually are involved in standard research on laboratory animals and are hard to convince of the value of conducting research on “exotic” animals. One reason might be that the #OneHealth concept of a common health denominator is not so widespread. Considering all the projects reviewed in this paper, it took years, sometimes decades, to get an appropriate funding, including for the marine worm project on Arenicola marina which is the most advanced in practical clinical application as indicated above. HEMARINA Académie des sciences Académie Nationale de Chirurgie ACADEMIE NATIONALE DE MEDECINE DE FRANCE Assemblée nationale Sénat Olivier Poivre d'Arvor Emmanuel Macron François Bayrou Yannick NEUDER Philippe Juvin https://lnkd.in/exJ6Btc4 https://lnkd.in/e7SD7kCQ

Last week, a delegation of EU-LIFE attended the #EUResearchArea Conference and the 26th #ERA Forum meeting. Marta Agostinho, EU-LIFE Executive Director, advocated for a constructive policy to #AnimalResearch and the development of new approach methodologies (#NAMs) following the active role of EU-LIFE in the co-creation of the ERA action on this topic. Her main points were: • 𝗔𝘀 𝗿𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗶𝗻𝘀𝘁𝗶𝘁𝘂𝘁𝗲𝘀 𝘄𝗲 𝗮𝗿𝗲 𝗳𝘂𝗹𝗹𝘆 𝗰𝗼𝗺𝗺𝗶𝘁𝗺𝗲𝗻𝘁 𝘁𝗼 𝘁𝗵𝗲 𝗱𝗲𝘃𝗲𝗹𝗼𝗽𝗺𝗲𝗻𝘁 𝗮𝗻𝗱 𝘂𝘀𝗲 𝗼𝗳 𝗡𝗔𝗠𝘀 that help to reduce the use of animals in research and regulatory testing. Likewise, we are fully committed to the Three Rs principle (Replacement, Reduction and Refinement). • Researchers are the ones developing NAMs, so 𝘁𝗵𝗲 𝘀𝗰𝗶𝗲𝗻𝘁𝗶𝗳𝗶𝗰 𝗰𝗼𝗺𝗺𝘂𝗻𝗶𝘁𝘆 𝗶𝘀 𝗮 𝗸𝗲𝘆 𝗽𝗹𝗮𝘆𝗲𝗿 for the success of any policy on NAMs and must be part of it at all stages. • The main value of this ERA action is the capacity to 𝗽𝗿𝗼𝗺𝗼𝘁𝗲 𝗰𝗼𝗼𝗿𝗱𝗶𝗻𝗮𝘁𝗶𝗼𝗻 𝗮𝗺𝗼𝗻𝗴 𝗠𝗲𝗺𝗯𝗲𝗿 𝗦𝘁𝗮𝘁𝗲𝘀, most specially at the regulatory stage; global coordination beyond the EU is also critical. • This action will only contribute to EU competitiveness if it allows the advancement of biomedical research and helps move science forward, 𝗯𝗮𝘀𝗲𝗱 𝗼𝗻 𝘀𝗰𝗶𝗲𝗻𝘁𝗶𝗳𝗶𝗰 𝗰𝗿𝗶𝘁𝗲𝗿𝗶𝗮 and not on political timelines. • The 𝘁𝗿𝗮𝗶𝗻𝗶𝗻𝗴 𝗮𝗻𝗱 𝗲𝗱𝘂𝗰𝗮𝘁𝗶𝗼𝗻 component of the action towards all actors - researchers, regulators, policy makers and citizens - is paramount. Informed policies must be based on broader understanding of the complexity of the biology behind biomedical research and on the potential risks, gains and impacts of the policies. Find out more here 🔗 https://bit.ly/3XUYnI0 #EuropeanResearch #ExcellentResearch

This month we will release our evaluation of the transition-opinion 1.0: transition towards non-animal science innovations, that was published in 2016. During the international conference '3Rs and NAMs: all-inclusive?' on 19 June 2024, our NCad member Jan-Bas Prins presented the preliminary results of this evaluation. Watch his presentation below. #transitionanimalfreeinnovation #animalfree #NAMs

Alternatives to Laboratory Animals - Latest Publication with Prof. DI Dr. Winfried Neuhaus - European network project IMPROVE COST Actions are European network projects whose work is funded by the European Commission. The aim of the IMPROVE network is to improve the quality of biomedical science with the help of concepts from the 3R area. The 3R principles deal with avoiding, reducing and refining animal testing; the 3R principles are also anchored in national law via European Regulation 2010/63. Within the network, working groups were installed on the scientific quality and translatability of preclinical data to humans, on the implementation of the 3R principles, on the dissemination of the 3R principles and on 3Rs in training. In addition to these main working groups, a cross-group working group on ethical topics has been etsablished. In addition, clearly defined questions are worked on together by the now over 230 participants. The COST Action IMPROVE has been running for 2 years and is led by Prof. DI Dr. Winfried Neuhaus. Details about the presentation of this network project can be found in the journal Alternatives to Laboratory Animals via the following link: https://lnkd.in/dw5DHZ7r #research #3Rs #replacementrefinementreduction  #alternativestoanimaltesting #alternativestolaboratoryanimals #laboratorytesting #biomedicalscience #medicalethics #medizinstudium #medizinstudiumösterreich #medicaldegree #studiereninöserreich #austria #nö #wienerneustadt #krems #danubeprivateuniversity

🚨 Reflecting on an inspiring 2-day workshop in Berlin on Early Warning Systems for vector-borne diseases 🚨 🌍 CLIMOS workshop in Berlin brought together experts from across Europe to tackle the pressing issue of vector-borne diseases, particularly #leishmaniasis. The discussions around co-creating an Early Warning System were both eye-opening and motivating. 🔹 It's essential to engage with #veterinarians and health professionals, highlighting the importance of cross-field collaboration. 🔹 The insights gained and the connections made during this workshop reaffirmed the importance of early warning systems in safeguarding public health. 🙏 A huge thank you to the CLIMOS team and all the experts who contributed. #PublicHealth #EarlyWarningSystem #VectorBorneDiseases Take a look at our partners ⤵ Universidade Nova de Lisboa , Istituto Superiore di Sanità , Charles University , Wageningen University & Research , Karlsruhe Institute of Technology (KIT) , University of Warwick , Research UP IAM and UP FAMNIT (University of Primorska) , Universidad de Murcia , Helmholtz Centre for Environmental Research (UFZ) , Ege University , Zentrix Lab, University of Haifa, F6S Innovation , Irset, Institut de recherche en santé, environnement et travail (UMR_S Inserm 1085), Hacettepe University , Trilateral Research , Université de Reims Champagne-Ardenne , Technical University of Crete , Ministry of Health Israel , Predictia Intelligent Data Solutions , Lancaster University , Ministero della Salute , Medical University of Vienna , Università degli Studi di Napoli Federico II (UniNa) / University of Naples Federico II , CubexLab , Turkish Ministry of Health , The Open Geospatial Consortium (OGC) , Aix-Marseille University , Institute for Medical Research European Climate-Health Cluster ⤵ @BlueAdaptEU, TRIGGER EU Project, #CATALYSE, HIGH Horizons EU, and IDAlert Collaborations  ⤵ Leishmaniasis Advocacy Network

Are you ready for this?! SEVEN POSTERS PRESENTATIONS: 1. Esteban (Jimenez) - MS: Prepartum acetylsalicylic acid in over-conditioned and nulliparous cows: Effects on reproductive performance and milk components. Abstract #: 2636 2. Pedram (Zarei) - MS: Effects of postpartum acetylsalicylic acid administration and calcium supplementation on production, reproductive performance, and culling in Holstein dairy cows. Abstract #: 2637 3. Jennine (Lection) – PhD: Effects of prepartum acetylsalicylic acid administration on local reproductive inflammation in postpartum Holstein dairy cattle. Abstract #: 2238  4. Raul (Sorto) - PhD: Prepartum acetylsalicylic acid effects on colostrum and passive immune transfer in neonatal Holstein calves. Abstract #: 2196 5. Raul (Sorto) - PhD: Prepartum acetylsalicylic acid effects on metabolic status and systemic inflammation in preweaned Holstein calves. Abstract #: 2197 6. Lydia (Periconi) - Undergraduate: Prepartum acetylsalicylic acid effects on growth and health during the preweaning period in Holstein calves. Abstract #: 2198 7.  Adrian (Barragan): Metabolic and inflammatory biomarker patterns in high-priority cow groups during the transition period. Abstract #: 2310 TWO ORAL PRESENTATIONS: 1.  Esteban (Jimenez) – MS: Prepartum acetylsalicylic acid in over-conditioned and nulliparous cows: Effects on metabolic stress and inflammatory status. Abstract #: 1593  2.  Pedram (Zarei) – MS: Effects of postpartum acetylsalicylic acid administration and calcium supplementation on metabolism, inflammation, and health in Holstein dairy cows. Abstract #: 1310 TWO 3-MIN SPOTLIGHT INVITED PRESENTATIONS: 1. Jennine’s poster: Abstract #: 2238  2.  Adrian’s poster: Abstract #: 2310 Collaborative presentation – Dr. Pitta’s Lab: 1.  Alexander (Post): Differential effects of prepartum acetylsalicylic acid administration on microbiome composition and volatile fatty acid production in nulliparous and parous cows. Abstract #: 2638 2024 ADSA Annual Meeting, here we go! Please stop by to say Hi and chat about our latest research and future collaborations 😉 ! https://lnkd.in/e7tKbWCQ

We seem to have learnt very little from the global pandemic: 1. A pandemic the world’s leading epidemiologists have been expecting because they knew that humans are vulnerable because the line between us and exotic animals had long been breached for legal trade purposes. 2. Which is now driving up the legal ‘harvesting’ for the trade of primates for the pharmaceutical industry, as they increase research to prepare for the next pandemic. 3. And, as a result, exposing people to stressed and immune-compromised primates, increasing the risk of the next pandemic. I hear you saying, but if business and industry are doing the right thing and only buying from the legal trade what’s the problem? In addition to poor monitoring and regulation, a 2020 survey and report into green crime in company supply chains found of the business respondents who admitted they knew about environmental crime, a substantial 65% know or suspect that third parties they conduct business with may have been involved in a range of illegal, environmentally damaging activities. Only 16% of respondents say that they would report a third-party breach externally; no one is telling the necessary authorities. And, 63% of respondents agree that the economic climate is encouraging organisations to take regulatory risks in order to win new business. The trade in lab animals is booming, and it isn't all legal: https://lnkd.in/gzmVuFZg

What an autumn for COST_TEATIME! So many activities in less than two months! Can't resist summarizing it here, read it or leave it! Meetings: - Sept 2-3: More than 40 experts in #animalwelfare #datascience gathered for two days in Brussels COST Association - European Cooperation in Science and Technology to discuss the challenges and opportunities of automated home-cage monitoring in advancing #animalresearch #3Rs and how to tackle the major hurdles in managing large datasets, scaling technology and how to make it accessible for fast decisions on humane intervention points. Thanks sara wells Hamish Forrest Oliver Stiedl Aurora Brønstad Petra Seebeck and many others! - Sept 23-24: Group of young TEATIME researchers met in Tartu, to present and discuss their research in relaxed and friendly atmosphere - indeed, before shiny success there are a lot of failures, learning from those, difficult decisions, gaining experience, skills - that's what research is, and that's why we need networking and communication. Nicely summarized by Davor Virag in his presentation "PhD-chaos" motivating everyone to speak up! All agreed that such meetings (also training schools) are very valuable and we need to find sustainable ways for supporting early career researchers also in future. - Oct 3-4: Rasneer Bains and Hilary Gates hosted a meeting Mary Lyon Centre at MRC Harwell - where Jan Rozman Otto Kalliokoski Pawel Boguszewski led discussion (together with Leonardo Restivo, MSc, PhD , Michael Ashby , Lars Lewejohann et al) on data sharing, repositories and metadata - essential topics for finalizing a roadmap for innovations in data analysis, data curation and ontologies - deliverable for upcoming, last grant period. The Pathway to Automation - From Home Cages to Animal Welfare. Finally - important funding instrument - Short Term Scientific Missions STSM for learning and sharing skills and knowledge: Adam Brosnan visiting Daniela Domingues in Paris Brain Institute Philipp Villiger visiting Morten Dall in Copenhagen Novo Nordisk Foundation Center for Basic Metabolic Research Aurora Hämäläinen visiting Sabine Hölter-Koch Helmholtz Munich German Mouse Clinic Last but not least - Many Thanks to Angelo Basteris and Aldona Gembalik for excellent support to our Action throughout these years!

"Exciting times at ATNT Laboratories as we prepare to unveil our state-of-the-art Rodent Isolator Facility! 🐁🔬 This facility is dedicated to the breeding of SOPF mice, advancing research and innovation in the field. On 18th October 2024, we will host a Scientific Seminar featuring renowned experts from The Jackson Laboratory, followed by an exclusive tour of our new facility. Stay tuned for insights and updates from this special day! #ATNTInnovation #SPFMice #ScientificExcellence"

#TPcorporate - 𝗪𝗲 𝗵𝗮𝗱 𝘁𝗵𝗲 𝗵𝗼𝗻𝗼𝗿 𝗼𝗳 𝗶𝗻𝘁𝗲𝗿𝘃𝗶𝗲𝘄𝗶𝗻𝗴 𝗗𝗿. 𝗠𝗶𝗿𝗶𝗮𝗺 𝗗𝗶𝗮𝗺𝗲𝗻𝘁, Head of the Vivarium Department of Experimental Cancer at the 𝗜𝗻𝘀𝘁𝗶𝘁𝘂𝘁𝗼 𝗱𝗲 𝗢𝗻𝗰𝗼𝗹𝗼𝗴𝗶́𝗮 '𝗔́𝗻𝗴𝗲𝗹 𝗛. 𝗥𝗼𝗳𝗳𝗼' in Buenos Aires, Argentina. The doctor told us that: "𝗧𝗵𝗲 𝘄𝗲𝗹𝗳𝗮𝗿𝗲 𝗼𝗳 𝗹𝗮𝗯𝗼𝗿𝗮𝘁𝗼𝗿𝘆 𝗮𝗻𝗶𝗺𝗮𝗹𝘀 𝗽𝗹𝗮𝘆𝘀 𝗮 𝗰𝗿𝗶𝘁𝗶𝗰𝗮𝗹 𝗿𝗼𝗹𝗲 𝗶𝗻 𝘁𝗵𝗲 𝗽𝗿𝗼𝗱𝘂𝗰𝘁𝗶𝗼𝗻 𝗼𝗳 𝗿𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗮𝗻𝗶𝗺𝗮𝗹𝘀 𝗮𝗻𝗱 𝘁𝗵𝗲 𝘀𝗰𝗶𝗲𝗻𝘁𝗶𝗳𝗶𝗰 𝗶𝗻𝘁𝗲𝗴𝗿𝗶𝘁𝘆 𝗼𝗳 𝗼𝘂𝗿 𝘄𝗼𝗿𝗸. Any alterations made to the laboratory animal environment must prioritize enhancing their physiological well-being and providing stimuli tailored to their species-specific needs. With this principle in mind, 𝘁𝗵𝗲 𝗻𝗲𝘄 𝗩𝗶𝘃𝗮𝗿𝗶𝘂𝗺 𝗲𝗻𝘀𝘂𝗿𝗲𝘀 𝘁𝗵𝗲 𝗾𝘂𝗮𝗹𝗶𝘁𝘆 𝗮𝗻𝗱 𝗿𝗲𝗽𝗿𝗼𝗱𝘂𝗰𝗶𝗯𝗶𝗹𝗶𝘁𝘆 𝗼𝗳 𝗿𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗲𝗻𝗱𝗲𝗮𝘃𝗼𝗿𝘀. We have the capability to maintain 𝗱𝗶𝗴𝗶𝘁𝗶𝘇𝗲𝗱 𝗿𝗲𝗰𝗼𝗿𝗱𝘀 𝗼𝗳 𝗲𝗻𝘃𝗶𝗿𝗼𝗻𝗺𝗲𝗻𝘁𝗮𝗹 𝗰𝗼𝗻𝗱𝗶𝘁𝗶𝗼𝗻𝘀 in all animal rooms and receive real-time alerts for any deviations. We've also implemented a double-door autoclave in the washing area, as well as a dedicated clean storage area". 𝗗𝗼𝗻'𝘁 𝗺𝗶𝘀𝘀 𝘁𝗵𝗲 𝗳𝘂𝗹𝗹 𝗮𝗿𝘁𝗶𝗰𝗹𝗲. You can find it in our 𝗻𝗲𝘄𝘀𝗹𝗲𝘁𝘁𝗲𝗿 𝗽𝗮𝗻𝗼𝗿𝗮𝗺𝗮 at the following link: https://buff.ly/3vqQyOS #Tecniplast