Humanitas Research

🗣️ Yesterday, we had the pleasure of welcoming #YvesDelneste – Head of the Innate Immunity and Cancer Laboratory at the Angers Cancer and Immunology Research Center. Introduced by Sebastien Jaillon, Delneste delivered a compelling seminar titled "Impact of Lactic Acid and Acetoacetate on Human Macrophages." He shared his latest findings on immune metabolism and macrophage polarisation, offering valuable insights into the tumor microenvironment and the immune response to cancer. A heartfelt thank you to Yves Delneste and Sébastien Jaillon for an engaging discussion and an inspiring exchange of ideas! #HumanitasResearch #Hunimed #Immunology #Metabolism #SeminarSeries

🔬🧬 We were thrilled to participate in #BIOEuropeSpring 2025: a truly invaluable event for the life sciences sector! Prof. Matteo G Della Porta – Director of the Center for Accelerating Leukemia/Lymphoma Research and the Leukemia Unit at Humanitas Research Hospital – took part in the roundtable 𝘔𝘪𝘭𝘢𝘯𝘰 & 𝘓𝘰𝘮𝘣𝘢𝘳𝘥𝘺: 𝘢 𝘙𝘦𝘴𝘦𝘢𝘳𝘤𝘩 𝘗𝘰𝘸𝘦𝘳𝘩𝘰𝘶𝘴𝘦, where he delivered a compelling talk on #SyntheticPatients in Cancer Research. Sharing the stage with him were moderator Marica Nobile, PhD – Director of Assobiotec; Prof. Luigi Naldini – Director of San Raffaele Telethon Institute for Gene Therapy (SR-Tiget); Marco Baccanti – Director of FITT - Fondazione Innovazione e Trasferimento Tecnologico; Marco Gorini – Project Head of Digital Health & Innovation at AstraZeneca. 🙌 A huge thank you to all for the inspiring discussions and invaluable insights. We look forward to continuing our journey in advancing innovation and research for the future of healthcare! #HumanitasResearch #Innovation #Networking #Biotech

🔬🤔 Why do some patients resist immunotherapy? Eduardo Bonavita – Junior Group Leader at Humanitas Research and Assistant Professor at Humanitas University, is investigating dendritic cells, key players in priming the immune system against tumours.   Funded by Worldwide Cancer Research, Bonavita’s lab will explore why some patients don’t respond to immunotherapy and develop strategies to reactivate these crucial immune cells. Using cutting-edge technologies, including preclinical models and multi-omics analyses, the research will focus on the transcription factor Bhlhe40, a potential regulator of anti-tumor immune responses.   Find out more 👉 https://shorturl.at/WtO0A   #HumanitasResearch #Hunimed #CancerResearch #Immunotherapy #DendriticCells

🗣️ Yesterday, we were honored to host Laura Baranello from Karolinska Institutet for an insightful seminar on the interaction between the cancer-driving protein MYC and topoisomerases – enzymes that help untangle and relax DNA strands, enabling cells to read and copy genetic information. Introduced by Enrico Lugli, Baranello – recently awarded the prestigious ERC Consolidator Grant – presented her latest research, unveiling how this interaction sustains cancer cell proliferation and how disrupting these processes could help halt disease progression. A huge thank you to Laura for sharing her expertise and advancing our understanding of cancer biology. We look forward to welcoming her back soon! #HumanitasResearch #Hunimed #CancerBiology #SeminarSeries

🚀 Join Our Mission to Transform Digital Health Humanitas Research Hospital! At Humanitas, innovation is at the heart of everything we do. Our Digital, AI & Innovation Team is on a mission to inform, support, and empower patients across Italy, making healthcare more accessible, seamless, and personalized. With over 20 digital platforms and 10M+ monthly users, we are leading the future of digital health—but we’re just getting started. We’re looking for a Digital Specialist to help us shape the next chapter. If you’re passionate about leveraging technology to improve healthcare and want to be part of a team that makes a real difference, this is your opportunity. 🔹 What you’ll do: ✔ Create innovative digital experiences that make healthcare easier for patients ✔ Optimize and expand our digital services & web platforms ✔ Work in a dynamic team driving digital transformation in healthcare 📍 Location: Milan, Italy | 🌍 Impact: Millions of lives Be part of something bigger. Join us in shaping the future of digital health, ai and HealthTech! 👉 Apply here: https://lnkd.in/dGEDDYbN #Hiring #DigitalHealth #Innovation #Ecommerce #HealthcareTech #Humanitas

🗣️ Yesterday, we had the pleasure of hosting Professor Caroline Dive. CBE – Scientific Director of the Cancer Research UK Manchester Institute and the Cancer Research UK National Biomarker Centre, for a seminar on Small Cell #LungCancer 🫁 biology and biomarkers, hosted by Eduardo Bonavita.   Professor Dive has been a pioneer in the field of #liquidbiopsies, with a strong focus on circulating tumour cells and cell-free DNA. Her research spans tumour biology, preclinical pharmacology, biomarker discovery and validation, bioinformatics, and, more recently, digital clinical trials.   Her outstanding contributions to cancer research have been widely recognised. She was elected a member of the European Molecular Biology Organization and was appointed Commander of the Order of the British Empire by Her late Majesty Queen Elizabeth II.   Thank you for sharing your passion and brilliant work!    #HumanitasResearch #Hunimed #Oncology #SCLC #SeminarSeries

👁️🔬 Intraocular surgery presents unique challenges due to its microscopic scale, requiring extensive hands-on training with models that accurately replicate the biomechanical properties of ocular tissues. To address this need, the #3DInnovationLab at Humanitas Research developed #Eye 3D-Phantom (Eye-3DP): a highly detailed, 3D-printed anatomical model designed to mimic the posterior segment of the eye.    The model was developed by researcher Nada Mansour, Paolo Oliva – Head of the 3D Innovation Lab, and Mario Romano 🇮🇹 – Full Professor of Ophthalmology at Humanitas University.   Using PolyJet Stratasys J850 Digital Anatomy printing technology, the team recreated key structures such as the sclera, choroid, retina, and vitreous humor with customised photopolymer resins, also allowing the subretinal bleb induction between the retina and choroid. As a result, Eye-3DP replicates the mechanical behavior of ocular tissues: a model capable of supporting complex intraocular procedures, essential for training in advanced vitreoretinal surgery, now covered by a patent.   By enhancing simulation realism, we aim to improve surgical proficiency and patient outcomes. 🚀 #HumanitasResearch #Hunimed #3DPrinting #SurgicalTraining #Ophthalmology #PrecisionSurgery #MedicalInnovation #Healthcare

🗣️ Yesterday, we had the pleasure of hosting Jean-Sébastien Hulot from the Paris-Cardiovascular Research Center for an inspiring seminar on the role of #inflammation in HFpEF (Heart Failure with preserved Ejection Fraction), one of the major challenges in modern cardiology. Introduced by Marinos Kallikourdis, Hulot discussed the basic and translational insights gained from the “PACIFIC-PRESERVED” research study he is coordinating. The discovery that inflammation plays a key role in this condition opens new perspectives for both research and clinical practice. A big thank you to Dr. Hulot for sharing his work with us and to our team for the engaging discussion! #HumanitasResearch #Hunimed #Cardiology #Immunology #SeminarSeries

🔬🎉 Congratulations to Dr. Marco Rasile and Dr. Erica Tagliatti for securing an Airalzh Grant for Young Researchers 2024! The team will investigate how the interaction between blood vessels and immune cells in the brain contributes to Alzheimer’s, focusing on gender differences. Their project, #TREASURE, tackles a pressing question: 𝑊ℎ𝑦 𝑑𝑜 𝑤𝑜𝑚𝑒𝑛 𝑚𝑎𝑘𝑒 𝑢𝑝 𝑡𝑤𝑜-𝑡ℎ𝑖𝑟𝑑𝑠 𝑜𝑓 𝐴𝑙𝑧ℎ𝑒𝑖𝑚𝑒𝑟’𝑠 𝑝𝑎𝑡𝑖𝑒𝑛𝑡𝑠? By studying the role of #microglia, the brain’s immune cells, and key proteins like TREM2, their work could pave the way for personalised therapies. Supported by AIRALZH - Associazione Italiana Ricerca Alzheimer Onlus, this research represents a crucial step towards better diagnostics, prevention, and treatments for Alzheimer’s. 🧬💡 Find out more 👉 https://shorturl.at/162xj #HumanitasResearch #Hunimed #Neuroscience #ResearchInnovation

🚀🌟 We are excited to share the launch of #PHOENIX, an EU-funded project set to advance biomedical research with next-generation organ-on-chip (OOC) technologies.   Founded by #Horizon Europe and coordinated by Politecnico di Milano, the project unites top-tier partners from Italy, Germany, the Netherlands, and Spain, integrating four precision technologies into OOC devices, and creating models that mimic human organs and tissues using stem cells.   Elisa Di Pasquale – Head of the Cardiovascular Stem Cell Biology Lab at Humanitas Research, leads the Humanitas unit in PHOENIX. Her team will explore LMNA-dependent cardiomyopathy, a genetic disorder linked to heart failure, using OOC devices to uncover new therapeutic strategies where none currently exist.   PHOENIX represents a leap toward ethical, efficient, and patient-centered biomedical innovation, enabling us to study diseases more accurately and develop therapies faster.   #PHOENIXProject #HumanitasResearch #Hunimed #BiomedicalInnovation