Protein function is much more dynamic than one gene, one enzyme, one function. Proteins adopt new structures and activities depending on their patterns of modification, their localization, their interactions, and more. On the latest episode of Translating Proteomics, host Parag Mallick and special guest Kathryn Lilley of the University of Cambridge discuss how researchers can dig into the dynamics of protein function and describe the impacts an evolved understanding of protein function will have on the life sciences. Find the episode here: https://lnkd.in/gCxVTqGn #TranslatingProteomics #Proteome #Proteomics #UnleashTheProteome #Biology #LifeSciences
Nautilus Biotechnology
Biotechnology Research
San Carlos, California 9,831 followers
Delivering on the Promise of the Human Proteome
About us
Born from the founders’ recognition that their diverse but complementary skills and experiences would enable them to successfully address challenges that others had not, Nautilus (Nasdaq: NAUT) set about solving a vexing problem: how to bring true proteomics to the world in a way that accelerates therapeutic development, dramatically improves medical diagnostics, and makes personalized and predictive medicine a reality. The extraordinary team at Nautilus represents a wide spectrum of disciplines and expertise, including: protein chemists, chip designers, molecular biologists, data scientists, material scientists, biophysicists, optical engineers, microfluidics engineers, bioinformaticists, software engineers, and more. Nautilus is positioned to revolutionize proteomics, transform the way drugs are developed, and significantly improve the way human health is managed.
- Website
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http://www.nautilus.bio
External link for Nautilus Biotechnology
- Industry
- Biotechnology Research
- Company size
- 51-200 employees
- Headquarters
- San Carlos, California
- Type
- Public Company
- Founded
- 2016
Locations
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Primary
San Carlos, California, US
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Seattle, Washington, US
Employees at Nautilus Biotechnology
Updates
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There are many levers of biological regulation that are not encapsulated in the central dogma. In this clip from #TranslatingProteomics, Parag and Andreas discuss some of these levers of regulation and why it's critical to learn more about them. Tomorrow, we'll release a brand new episode featuring special guest Kathryn Lilley where we'll dive even further into this regulation and what it means for protein function. #Biology #Proteomics #Proteome
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Nautilus Biotechnology reposted this
Great timing for this fascinating discussion about the power and potential of proteoform science in taking precision medicine to the next level in light of the recent announcement of #NobelPrize2024 in Chemistry centering on protein science. Thanks, Parag Mallick for highlighting Chemistry of Life Processes Institute director Neil Kelleher's unwavering dedication to mastering the human proteome for the benefit of all. Save this podcast for your next run, walk or commute! https://t.co/LYfsoj5lG6 #HumanProteoformProject #TranslatingProteomicsPodcast, Nautilus Biotechnology #proteomics Consortium for Top-Down Proteomics
In the season 2 premier of our Translating Proteomics podcast, Nautilus Co-Founder and Chief Scientist Parag Mallick got the exciting opportunity to chat with Northwestern University Professor, proteomics expert, and proteoform pioneer Neil Kelleher. They discuss the need to create new proteomics technologies that enable researchers to explore the diverse and dynamic versions of proteins actually found in biological systems - proteoforms. While most technologies today cannot see proteoforms (are "proteoform unaware"), Neil highlights a growing list of examples showing how proteoforms drive biology and how knowledge of them can accelerate biomarker discovery and drug development. https://lnkd.in/g9nNW3tf #Proteoforms #Proteoform #Proteomics #Proteome #Biotech #Biomarkers #DrugDevelopment #Biology #TranslatingProteomics
Translating Proteomics Episode 9 - Are Proteins a Myth with Neil Kelleher
https://www.nautilus.bio
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For decades, biology’s central dogma has dominated as a simplistic explanation of how proteins get made, but how do we move beyond the central dogma and create better models of biology? Parag Mallick and Andreas Huhmer of Nautilus weigh in on this episode of Translating Proteomics. https://lnkd.in/gvnah2Cm #UnleashTheProteome #NautilusBio #Proteome #ProteomicsRevolution #TranslatingProteomics
Beyond the central dogma - Forging a new era in biological discovery
https://www.nautilus.bio
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We're excited to attend #HUPO2024 in Dresden, Germany! We'll present exciting new data from the Nautilus Platform, dive into our recent work on Tau proteoforms, and answer your questions about all things Nautilus. Our team will be on-site all week at Booth 08 where we'll host AMA sessions with Nautilus Co-Founder and Chief Scientist Parag Mallick, and where you can submit your answers to our protein scavenger hunt for your chance to win a Nintendo® Switch™! You can find our HUPO 2024 talks and posters outlined here: https://lnkd.in/gWYab3ag We look forward to seeing you at the event! #Proteomics #Proteome #UnleashTheProteome #TeamMassSpec #Proteoforms #Proteoform
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We're hiring! Join the Nautilus team as a Manunfacturing Engineer and play a key role in scaling and optimizing the production of our proteomics platform. Learn more and apply here: https://hubs.li/Q02T4MBw0 #Proteomics #Engineer #Engineering #JobInSTEM #Career #ScienceCareer
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Nautilus Biotechnology reposted this
Congratulations to Seattle’s own David Baker on being named a Nobel laureate in Chemistry and his colleagues at the Institute for Protein Design, University of Washington for their tremendous contributions to advancing the understanding of protein folding and the ability to engineer novel proteins. As the co-founder (along with Parag Mallick) and CEO of Nautilus Biotechnology, I am thrilled at the potential that this and other recognition has to continue to build the momentum I’m seeing in protein-related research and investments. On behalf of myself and all of my colleagues at Nautilus, we salute your achievements and look forward to a future where a deeper understanding of proteins and their function lead to significant advancements in human health.
Announced early this morning, University of Washington biochemist and professor David Baker has won the 2024 Nobel Prize in Chemistry for his pioneering work in designing new proteins that can neutralize viruses, target cancer cells, and more. Read more from UW Medicine here: https://lnkd.in/gh7-vDQP
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Nautilus Biotechnology reposted this
So well deserved! Could not be more excited for David Baker for being named a Nobel laureate for computational protein design. David is such a special scientist and an inspiration - to this day you find him knee deep in code at every opportunity. In addition, his commitment to open science and his extensive family tree has transformed the field. Equally thrilled for Demis Hassabis and John M. Jumper being recognized for their work on protein structure prediction. When I (along with Sujal Patel) co-founded Nautilus Biotechnology it was based on a strongly held belief that a deeper understanding of proteins and the proteome held the potential to revolutionize biomedical research and unlock untold advancements in target identification, therapeutic development, and human health. This recognition for David, Demis, and John will contribute to the steadily rising tide that continues to lift so many protein-related research initiatives. Heartiest congratulations to all, including David’s team at the Institute for Protein Design, University of Washington.
This year’s Nobel Prize laureate in chemistry David Baker was born in 1962 in Seattle, WA, USA. He earned his PhD 1989 from the University of California, Berkeley, CA, USA and is currently a professor at the University of Washington, Seattle, WA, USA and a investigator at Howard Hughes Medical Institute (HHMI), USA. https://lnkd.in/eNb9qBz2
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Broadscale proteomics studies are designed to quantify proteins across the wide dynamic range of the proteome. Though difficult with current technologies, we're designing the Nautilus Platform to make broadscale proteomics accessible to many more researchers and hope their studies will launch entire new research programs. Learn more in our latest blog post: https://lnkd.in/d-eFMcXE #Proteomics #BroadscaleProteomics #DiscoveryProteomics #Proteome
What is broadscale proteomics?
https://www.nautilus.bio
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Proteoforms are the active forms of proteins with all their attendant modifications, splicing changes, and more. So are proteins a myth? Neil Kelleher provides his answer in this clip from Translating Proteomics: Learn more about proteoforms and their biological importance in the full episode: https://lnkd.in/g9nNW3tf #Proteomics #Proteoforms #Proteome #TranslatingProteomics #Podcast