Battelle’s Post

Imagine a world where your medication is designed just for you. That world is closer than you think. Battelle's latest blog, 'A Custom Pill for Every Patient,' highlights how 3D printing technology is personalizing medicine to fit unique patient profiles. https://okt.to/ltvNrE #drugdelivery #PersonalizedMedicine

🔬💡 Exciting News in Science & Pharma! 🚀 Additive manufacturing, often referred to as 3D printing, is leading a groundbreaking transformation in the pharmaceutical industry! 🏥💊 Imagine a world where medication isn't one-size-fits-all. Thanks to 3D printing, we're stepping into the era of patient-centric dosage development. 🌟 With this innovative technology, we can create custom-shaped, sized, and timed-release dosage forms right at the patient's bedside. It's like tailor-made medicine! 👩⚕️👨⚕️ This journey began in rapid prototyping and has now firmly entered the biomedical field, revolutionizing the pharmaceutical industry's pace of innovation. 🔄💊 3D printing opens up avenues for personalized medicine, controlled-release dosage forms, organ-on-a-chip models, and even implants! The possibilities are endless. 🌐🩺 Just a few years ago, the idea of using 3D printing in the formulation development pipeline, from preformulation to First-in-Human trials, seemed implausible. 🚫🤔 But today, it's not just a possibility; it's a reality. 3D printing is making its way into front-line clinical trials, offering personalized services to trial patients. 🏨💉 This is a monumental leap forward, and it's an exciting time to be part of the pharmaceutical and scientific community. Let's continue to embrace innovation and shape the future of healthcare together! 🧬 **Personalized Medicine**: 3D printing allows for medications tailored to an individual's unique needs. This means patients can receive treatments that are more effective and have fewer side effects, ultimately improving their quality of life. 🌡 **Controlled Release**: With 3D printing, we can precisely control how and when medications are released in the body. This is a game-changer for conditions that require carefully timed drug delivery, like diabetes or chronic pain management. 🧪 **Organ-on-a-Chip Models**: Researchers can now create miniature models of organs using 3D printing, enabling more realistic testing of new drugs. This speeds up drug development and reduces the need for animal testing. 🩺 **Implants**: 3D printing has revolutionized the creation of medical implants. Custom implants can be designed and produced quickly, leading to faster recovery times and improved patient outcomes. 🔬 **Innovation Acceleration**: The adoption of 3D printing has accelerated the pace of innovation in the pharmaceutical industry. Researchers and companies are constantly exploring new possibilities and pushing the boundaries of what's possible in drug development. 💊 **Clinical Trials**: As mentioned earlier, 3D printing is now being integrated into clinical trials. This allows for the creation of personalized medication doses for trial participants, increasing the chances of successful outcomes and reducing adverse reactions. 🌌🔬🤝 #3DPrinting #PharmaceuticalInnovation #ScienceMatters 🌟🔍🚀 #PharmaInnovation #HealthcareRevolution #additivemanufacturing

The Rise of 3D Printed Drugs. Imagine being able to take personalized 3D printed tablets tailored for you. Researchers from the Centre for Additive Manufacturing (CfAM) at University of Nottingham used Multi-material Inkjet 3D printing (MM-IJ3DP) to create tablets with a variety of medicines timed to be released a specific times, "enbaling highly customized drug delivery sytems with unparalleled precision." This will also simplify medication regimes and allow for highly personalized medicines for specific patients. Work continues to expand the number of drugs that can be printed. 3Dnatives Centre for Additive Manufacturing (CfAM) at University of Nottingham Yinfeng He University of Nottingham Felicity Rose #3dprinting #3dprinteddrugs #personalizedmecidine #medicine #pharmaceuticals #healthcare #customization #research #futurist #trendforecasting

https://lnkd.in/ewzjaiQf "Here are just a few potential advantages of 3D drug printing—a new system for manufacturing drugs and treatments onsite at pharmacies, healthcare facilities, and other remote locations..." Stringent quality controls will of course be required, but there are also enormous advantages including make-to-order.

New Article Online! Welcome your read. 🔓 An overview of current advances and pharmaceutical uses of 3D and 4D printing 👤 Authors: Pankaj Sharma, Vinay Jain (Dr Vinay Jain) 📖 Read Online: https://lnkd.in/g2cmnQ8B 📄 PDF: https://lnkd.in/gs3b6_w9 🔖 Included in Special Issue: Exploration of 3D and 4D Printing in the Biomedical and Personalized Medicine Fields: Merits and Challenges (https://lnkd.in/g2Js7b4P)

𝗔𝗺𝗼𝗿𝗽𝗵𝗼𝘂𝘀 𝘀𝗼𝗹𝗶𝗱 𝗱𝗶𝘀𝗽𝗲𝗿𝘀𝗶𝗼𝗻 𝗼𝗳 𝗮 𝗯𝗶𝗻𝗮𝗿𝘆 𝗳𝗼𝗿𝗺𝘂𝗹𝗮𝘁𝗶𝗼𝗻 𝘄𝗶𝘁𝗵 𝗳𝗲𝗹𝗼𝗱𝗶𝗽𝗶𝗻𝗲 𝗮𝗻𝗱 𝗛𝗣𝗠𝗖 𝗳𝗼𝗿 𝟯𝗗 𝗽𝗿𝗶𝗻𝘁𝗲𝗱 𝗳𝗹𝗼𝗮𝘁𝗶𝗻𝗴 𝘁𝗮𝗯𝗹𝗲𝘁𝘀 This study focuses on the combination of three-dimensional printing (3DP) and amorphous solid dispersion (ASD) technologies for the manufacturing of gastroretentive floating tablets. Employing hot melt extrusion (HME) and fused deposition modeling (FDM), the study investigates the development of drug-loaded filaments and 3D printed (3DP) tablets containing felodipine as model drug and hydroxypropyl methylcellulose (HPMC) as the polymeric carrier. Prior to fabrication, solubility parameter estimation and molecular dynamics simulations were applied to predict drug-polymer interactions, which are crucial for ASD formation. Physical bulk and surface characterization complemented the quality control of both drug-loaded filaments and 3DP tablets. The analysis confirmed a successful amorphous dispersion of felodipine within the polymeric matrix. Furthermore, the low infill percentage and enclosed design of the 3DP tablet allowed for obtaining low-density systems. This structure resulted in buoyancy during the entire drug release process until a complete dissolution of the 3DP tablets (more than 8 h) was attained. The particular design made it possible for a single polymer to achieve a zero-order controlled release of the drug, which is considered the ideal kinetics for a gastroretentive system. Accordingly, this study can be seen as an advancement in ASD formulation for 3DP technology within pharmaceutics. Continue reading here: https://lnkd.in/eBY79sp6 by: Gloria Mora Castaño, Mónica Millán-Jiménez, Andreas Niederquell, Monica Schönenberger, Fatemeh Shojaie, Pharm.D, Martin Kuentz, Isidoro Caraballo #3dprinting #excipients #pharmaceuticals

Revolutionizing Medicine with 3D Printing. Dive into the future of personalized medication with MB Therapeutics! #3DPrinting #3DScanning #AdditiveManufacturing #Technology #Innovation #Manufacturing #Engineering #beaconscanner https://lnkd.in/dxP625zR!

Innovating the Future of Pharmaceuticals: A New Chapter in 3D Printing and AI Excited to unveil our latest milestone in pharmaceutical innovation: a book chapter titled "3D Printing of Pharmaceutical Products Using AI Technology," published in a prestigious volume accessible here: https://lnkd.in/dP64K8pT. This chapter represents a significant advance in the field, blending AI with 3D Printing (Additive Manufacturing) to redefine what's possible in drug production and personalized medicine. We delve into how this cutting-edge integration overcomes traditional barriers in 3D printing, such as enhancing production speeds, enabling automation, and facilitating the creation of complex, custom-tailored drug formulas. Our collaborative effort sheds light on the untapped potential of AI and Machine Learning to revolutionize pharmaceutical manufacturing, offering a blueprint for future innovations that prioritize efficiency, precision, and patient-specific care. This work not only paves the way for individualized medication solutions but also sets a new standard for the industry, moving us towards a more personalized, patient-centric healthcare model. I have heartfelt gratitude to my co-authors, Anand Kumar S, Dr. Mitali Pareek, Sneha Sharma, and Dr Rajkumar Velu, for their unwavering dedication and profound insights. We are proud to contribute to this transformative journey in healthcare technology. #3DPrinting #AIinPharma #AdditiveManufacturing #PharmaceuticalManufacturing #DigitalHealth #InnovationInHealthcare

𝐀 𝐂𝐨𝐦𝐩𝐥𝐞𝐭𝐞 𝐆𝐮𝐢𝐝𝐞 𝐭𝐨 𝟑𝐃 𝐏𝐫𝐢𝐧𝐭𝐞𝐝 𝐃𝐫𝐮𝐠𝐬- [𝐏𝐃𝐅 𝐆𝐮𝐢𝐝𝐞] ➡ 𝐃𝐨𝐰𝐧𝐥𝐨𝐚𝐝 𝐅𝐫𝐞𝐞 𝐏𝐃𝐅 𝐂𝐨𝐩𝐲: https://lnkd.in/dc4ubvjC 3D printed medication or 3D printed drug refers to a #medication that is manufactured using #3D #printing technology which is an #additive #manufacturing approach. 3D printing enables the creation of customized and precise dosage forms tailored to the specific needs of patients. As such, the field of 3D drug printing is a part of #personalized or precision medicine. Furthermore, 3D drug printing is a sub-field of #pharmaceutics. The most common application of 3D printing in pharmaceuticals is the production of pills or tablets. 3D printing offers precise dosing, the ability to design tablets with improved release profiles, and the capability to combine #multiple #medications into a single tablet. Current developments primarily focus on 3D printing drugs for pediatric, geriatric, psychiatry, and neurology patients, where dosage adjustments are often necessary based on a patient's condition, and patient adherence is a challenge. The first 3D-printed tablet to receive FDA approval was #Spritam (#levetiracetam), an anti-epileptic medication. 𝐓𝐞𝐜𝐡𝐧𝐨𝐥𝐨𝐠𝐢𝐞𝐬 𝙑𝙖𝙧𝙞𝙤𝙪𝙨 𝙩𝙚𝙘𝙝𝙣𝙤𝙡𝙤𝙜𝙞𝙚𝙨 𝙝𝙖𝙫𝙚 𝙗𝙚𝙚𝙣 𝙙𝙚𝙫𝙚𝙡𝙤𝙥𝙚𝙙 𝙩𝙤 𝙘𝙧𝙚𝙖𝙩𝙚 3𝘿-𝙥𝙧𝙞𝙣𝙩𝙚𝙙 𝙢𝙚𝙙𝙞𝙘𝙖𝙩𝙞𝙤𝙣𝙨, 𝙞𝙣𝙘𝙡𝙪𝙙𝙞𝙣𝙜: • 𝐒𝐞𝐦𝐢-𝐬𝐨𝐥𝐢𝐝 𝐞𝐱𝐭𝐫𝐮𝐬𝐢𝐨𝐧 • 𝐅𝐮𝐬𝐞𝐝 𝐝𝐞𝐩𝐨𝐬𝐢𝐭𝐢𝐨𝐧 𝐦𝐨𝐝𝐞𝐥𝐢𝐧𝐠 • 𝐒𝐭𝐞𝐫𝐞𝐨𝐥𝐢𝐭𝐡𝐨𝐠𝐫𝐚𝐩𝐡𝐲 • 𝐒𝐞𝐥𝐞𝐜𝐭𝐢𝐯𝐞 𝐥𝐚𝐬𝐞𝐫 𝐬𝐢𝐧𝐭𝐞𝐫𝐢𝐧𝐠 𝐓𝐡𝐞 𝐠𝐥𝐨𝐛𝐚𝐥 #𝟑𝐃 #𝐩𝐫𝐢𝐧𝐭𝐞𝐝 𝐝𝐫𝐮𝐠𝐬 𝐦𝐚𝐫𝐤𝐞𝐭 𝐬𝐢𝐳𝐞 𝐰𝐚𝐬 𝐞𝐱𝐡𝐢𝐛𝐢𝐭𝐞𝐝 𝐚𝐭 𝐔𝐒𝐃 𝟕𝟑.𝟎𝟐 𝐦𝐢𝐥𝐥𝐢𝐨𝐧 𝐢𝐧 𝟐𝟎𝟐𝟑 𝐚𝐧𝐝 𝐢𝐬 𝐩𝐫𝐨𝐣𝐞𝐜𝐭𝐞𝐝 𝐭𝐨 𝐡𝐢𝐭 𝐚𝐫𝐨𝐮𝐧𝐝 𝐔𝐒𝐃 𝟑𝟎𝟒.𝟓𝟐 𝐦𝐢𝐥𝐥𝐢𝐨𝐧 𝐛𝐲 𝟐𝟎𝟑𝟑, 𝐠𝐫𝐨𝐰𝐢𝐧𝐠 𝐚𝐭 𝐚 𝐂𝐀𝐆𝐑 𝐨𝐟 𝟏𝟓.𝟑𝟓% 𝐝𝐮𝐫𝐢𝐧𝐠 𝐭𝐡𝐞 𝐟𝐨𝐫𝐞𝐜𝐚𝐬𝐭 𝐩𝐞𝐫𝐢𝐨𝐝 𝐨𝐟 𝟐𝟎𝟐𝟒 𝐭𝐨 𝟐𝟎𝟑𝟑.

Insightful article in the field of 3D drug printing and thanks for the high regard of Triastek！#3DPrinting #drugdevelopment