Pratico Lab’s Post

Discover the groundbreaking research at Pratico Lab! 🧪🔬 Led by Dr. Domenico Pratico, the lab is on a mission to bring about the first life-changing Alzheimer’s treatment. Their focus? Oxidized lipids - small molecules that could be the hidden culprits behind aging and disease. Join us in exploring the cellular and molecular aspects of cell oxidative biology and their significance as potential therapeutic targets for neurodegenerative diseases. Together, we can envision a world free from Alzheimer’s fear, harm, and heartbreak, with memories to last a lifetime. Stay tuned for more updates from Pratico Lab! 🌐 www.drdomenicopratico.com | www.thepraticolab.com 📚 https://lnkd.in/ePYMYRWn 🧠 https://lnkd.in/eJjn_Shz 🐦 https://lnkd.in/e-NvsgBK 🖋️ https://lnkd.in/ecVzXE8D #PraticoLab #AlzheimersResearch #NeuroscienceBreakthroughs #OxidizedLipids #LifeChangingTreatment #DomenicoPratico #CellOxidativeBiology #NeurodegenerativeDiseases #ResearchInnovation #MemorySolutions #ScientificDiscovery #FutureofHealthcare #AlzheimersAwareness #BreakingBarriers #HopeForTheFuture #BrainHealth #Neuroscience #PraticoLab #AlzheimersTreatment #domenicopratico #praticodomenico

Can we prevent Alzheimer’s? This is the question that drives the pioneering research at Pratico Lab. Led by Dr. Domenico Pratico, the lab is on a mission to bring about the first life-changing Alzheimer’s treatment. Their focus is on the cellular and molecular aspects of cell oxidative biology, with a keen interest in small molecules like bioactive oxidized lipids. These molecules could play a significant role in the pathogenesis of several neurodegenerative diseases and serve as potential therapeutic targets against them. Join us as we delve into the mysteries of Alzheimer’s, fueled by hope and guided by science. Stay tuned for more updates from Pratico Lab! 🌐 www.drdomenicopratico.com | www.thepraticolab.com 📚 https://lnkd.in/ePYMYRWn 🧠 https://lnkd.in/eJjn_Shz 🐦 https://lnkd.in/e-NvsgBK 🖋️ https://lnkd.in/ecVzXE8D #AlzheimersResearch #brainalzheimer #AlzheimersResearch #BrainHealth #Neuroscience #PraticoLab #OxidativeBiology #BioactiveLipids #NeurodegenerativeDiseases #HopeInScience #AlzheimersTreatment #domenicopratico #praticodomenico #ResearchUpdate

Can we prevent Alzheimer’s? This is the question that drives the pioneering research at Pratico Lab. Led by Dr. Domenico Pratico, the lab is on a mission to bring about the first life-changing Alzheimer’s treatment. Their focus is on the cellular and molecular aspects of cell oxidative biology, with a keen interest in small molecules like bioactive oxidized lipids. These molecules could play a significant role in the pathogenesis of several neurodegenerative diseases and serve as potential therapeutic targets against them. Join us as we delve into the mysteries of Alzheimer’s, fueled by hope and guided by science. Stay tuned for more updates from Pratico Lab! 🌐 www.drdomenicopratico.com | www.thepraticolab.com 📚 https://lnkd.in/ePYMYRWn 🧠 https://lnkd.in/eJjn_Shz 🐦 https://lnkd.in/e-NvsgBK 🖋️ https://lnkd.in/ecVzXE8D #AlzheimersResearch #brainalzheimer #AlzheimersResearch #BrainHealth #Neuroscience #PraticoLab #OxidativeBiology #BioactiveLipids #NeurodegenerativeDiseases #HopeInScience #AlzheimersTreatment #domenicopratico #praticodomenico #ResearchUpdate

🥳 #Session_Chair Announcement We're excited to announce Assoc. Prof. Carla Masala, from the Università degli Studi di Cagliari will be the session chair of Session: Neurodegenerative Diseases. 📑Session Introduction: Different neurodegenerative diseases are associated with olfactory impairment. The degree of olfactory dysfunction may vary among different neurodegenerative diseases, such as Parkinson’s disease, Alzheimer’s disease, and progressive supranuclear palsy. In particular, in Parkinson’s disease, the olfactory deficits may precede the occurrence of motor symptoms; they are, therefore, often underestimated in patients during the early stages of the disease. This section aims to correlate olfactory dysfunction with neurodegenerative diseases, to evaluate the progression of pathology and the quality of life in patients. 🔎Look forward to meeting you in 2024 at 👉 https://brnw.ch/21wKxP9 📅Abstract submission deadline 25th June 2024 Submit the abstract today at 👉 https://brnw.ch/21wKxP6 📅Registration Deadline: 17th October 2024 🔗 Registration for free: 👉 https://lnkd.in/dnceD7Nu MDPI Scilit #ECBS2024 #BrainSciences #OpenAccess #FreeOfCharge #neuroscience #brain

In Australia, and around the world, the challenges of aging are becoming more relevant every day and there are teams of amazing researchers trying to understand the science of aging and how to manage this natural stage of life. If this is an areas of your research and you wanted to learn how SomaScan 7000 plex assay could be combined with mass spec, and other omics data, then take some time to listen to the webinar linked below #aging #precisionmedicine #proteomics #neurodegenerativedisease

Ncardia webinar today @10am featuring #ipscs for devt of treatments for #proteinopathies:

🧠 Exciting Update from the Kioloa Neurosciences Colloquium! 🧠 I'm delighted to share insights from my recent talk at the Kioloa Neurosciences Colloquium, where I delved into the intricate neural mechanisms underlying pain in Multiple Sclerosis (MS) and Fibromyalgia. Our preliminary data from our longitudinal study at Western Sydney University shed fascinating light on this complex topic. Understanding pain in MS is crucial for improving the quality of life for patients, and our study is dedicated to achieving that. We're investigating the potential biomarkers reflecting pain in MS and Fibromyalgia patients over time, offering invaluable insights into potential treatments and interventions. But we can't do it alone! We're actively seeking participants to join our study. If you or someone you know is living with MS or an autoimmune disease and is interested in contributing to cutting-edge research that could make a real difference, we'd love to have you on board. Want to learn more about our study or get involved? 👉 Feel free to reach out to me directly or visit the MS Australia website https://bit.ly/3QNSwjN for more information. Let's pave the way for a better understanding and management of pain in Multiple Sclerosis! #MultipleSclerosis #MSResearch #Fibromyalgia #Neuroscience #PainMechanisms #KioloaNeurosciencesColloquium #PhD #WesternSydneyUniversity

📢 Excited to announce the release of "Mechanisms of Disease Pathogenesis in Multiple Sclerosis," edited by Francisco Javier Quintana! This comprehensive book delves into MS, its clinical features, available biomarkers, and the mechanisms driving disease pathogenesis. It also covers the influence of genetic and environmental factors and highlights novel therapies for disease management. A must-read for neurologists, neuroimmunologists, and researchers dedicated to understanding neurodegeneration. Get your copy today: https://bit.ly/4b5WNGK #MultipleSclerosis #Neurodegeneration #NewBook #Neuroscience #ElsevierBooks

Mitophagy in neurodegenerative disease pathogenesis In this latest review, the authors delve into the critical role of #Mitophagy in maintaining cellular energy and ensuring homeostasis within neurons. 🧠 Highlighting mitochondria as the powerhouse of cells, the review emphasizes the importance of their health for neuron vitality. The paper meticulously explores how selective autophagy pathways, including #ERphagy, #Aggrephagy, and notably mitophagy, play pivotal roles in clearing damaged mitochondria, thus supporting the energy demands of neurons and preventing dysfunction. 🔄 The authors examine both #ParkinDependent and #ParkinIndependent mitophagy pathways under normal physiological conditions, shedding light on the complex mechanisms that underpin mitochondrial quality control. 🛠️ The review further discusses the profound implications of mitophagy in the pathogenesis of neurodegenerative diseases such as Alzheimer's, Parkinson's, and ALS, suggesting that mitophagy pathways might offer new avenues for therapeutic intervention. 💡 #Neurodegeneration #CellularBiology #TherapeuticTargets #Neuroscience #ResearchInsights link: https://lnkd.in/gqXB5M_w

🧠 Groundbreaking research offers new insights into Alzheimer’s disease (AD) progression. A study suggests that glucose metabolism in the posterior cingulate cortex (PCC), measured by the standard uptake value ratio (SUVR) from FDG PET imaging, could serve as a supplementary biomarker alongside amyloid-β (Aβ) and tau. Kaplan-Meier survival analyses indicate that combining PCC SUVR with CSF Aβ42 and ptau-181 enhances the predictive performance for the progression from cognitively unimpaired (CU) to AD. This correlation could revolutionize early prediction and prevention strategies in neurodegenerative diseases. #AlzheimersResearch #Neuroscience #Biomarkers https://lnkd.in/g4XcszB9