We're thrilled to announce that Dr Peter Jandus has joined the GCIR! Dr Jandus brings exceptional expertise in managing and researching #immunodeficiencies and #allergic diseases. His background includes research at Cambridge University Hospitals, UK, where he explored anti-cytokine antibodies, and clinical leadership at the University Hospitals of Geneva (HUG - Hopitaux Universitaires de Genève), where he manages outpatient care for adult immunodeficiency and allergy patients. His current research focuses on advancing diagnostic approaches for primary and secondary immunodeficiencies, and novel investigations into primary immunodysregulation disorders (PIRD). Welcome aboard! Check out his full profile here: https://lnkd.in/dyPAD-ch
Geneva Centre for Inflammation Research - UNIGE
Forschungsdienstleistungen
Our mission is to foster translational projects between fundamental and clinical research in inflammation
Info
Created in 2020 within the Faculty of Medicine at the University of Geneva, the Geneva Centre for Inflammation Research (GCIR) aims to promote scientific collaboration, translational research projects and interaction between academia and industry. The Centre's research focuses on diseases that have a major impact on the health of patients and society, such as rheumatoid arthritis, psoriasis, multiple sclerosis and respiratory infections. To facilitate the sharing and exchange of knowledge, the Centre organises an annual scientific symposium and quarterly seminars on specific topics. Check our website for the upcoming events and latest news: https://www.unige.ch/medecine/gcir/home
- Website
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https://www.unige.ch/medecine/gcir/home
Externer Link zu Geneva Centre for Inflammation Research - UNIGE
- Branche
- Forschungsdienstleistungen
- Größe
- 51–200 Beschäftigte
- Hauptsitz
- Geneva
- Gegründet
- 2020
- Spezialgebiete
- medicine, research, immunology, inflammation, autoimmune diseases, rheumatology, infectious diseases, virology, microbiology, circadian immunology, immunotherapy, multiple sclerosis, psoriasis, neuroinflammation, cell signalling und scientific symposia
Updates
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How can we better predict brain development challenges in extremely preterm infants? 🧠 This study, led by GCIR Professor Olivier Baud, re-evaluates Bronchopulmonary dysplasia (BPD) assessment timing, finding that a 40-week endpoint more accurately predicts neurodevelopmental outcomes at two years. Prophylactic hydrocortisone, shown to reduce BPD, might also help prevent later neurodevelopmental issues, offering a new approach to early care for these infants. #Pediatrics #Prematurity #NICU #NeurodevelopmentalImpairment #ProphylacticHydrocortisone #ProphylacticSteroids Full article in Pediatric Research: https://lnkd.in/dfqdUc9S Summary: https://lnkd.in/dsXyAKVX Faculté de médecine - UNIGE, University of Geneva, HUG - Hopitaux Universitaires de Genève
Bronchopulmonary dysplasia to predict neurodevelopmental impairment in infants born extremely preterm - Pediatric Research
nature.com
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Exciting advances in diagnosis and monitoring of #lupus in #women! Recent findings from the #SwissSLECohortStudy identify B-cell DN3 as a key factor in systemic lupus erythematosus (SLE) in women. The researchers found that cases of active SLE show a marked increase in DN3 cells, with reduced CD19 levels directly correlating with disease severity. With the #TLR7 gene possibly contributing to immune dysregulation, this study opens new doors for targeted therapeutic approaches to SLE. Summary: https://lnkd.in/d9UCShT2 Full: https://lnkd.in/d6DQiPuC In the Journal of Translational Immunology GCIR Professor Stephanie Hugues, Department of Pathology and Immunology, Faculté de médecine - UNIGE, University of Geneva. First author: Professor Carlo Chizzolini #SystemicLupusErythematosus #BCells #DoubleNegativeBCells #AtypicalMemory #CXCR5 #CD11c #TLR7 #ExtrafollicularResponse #AutoimmundeDisease #Immunology #Biomarkers #ScientificArticle #GenderMedicine
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"#Influenza A virus and host pathology: It takes two to tango (and sometimes more)" Join us for GCIR Prof. Mirco Schmolke's lecture next Thursday! 🗓️Thu 7 Nov 🕛12h 📍CMU A Renold #Flu #InnateImmunity #Virology #Microbiology Department of Microbiology and Molecular Medicine, Geneva Centre for Inflammation Research - UNIGE, Faculté de médecine - UNIGE, University of Geneva https://lnkd.in/drK4FhST
Agenda des événements
agenda.unige.ch
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Join us for an exciting GCIR seminar on Immune Cell Signalling! ✨ 📅 Friday, November 22, 2024 📍 CMU, Müller Auditorium ⏰ 2 pm to 3:30 pm, followed by a coffee reception Programme: Prof. Susanna Zierler, Johannes Kepler Universität Linz, Austria, & Ludwig-Maximilians-Universität München, Germany 🕒 2:00 - 2:30 pm *TRPM7 Channel-Kinase Function: From Cellular Signaling to Immune System Homeostasis* Prof. Zierler will reveal her lab’s fascinating work on the TRPM7 channel-kinase and its dual role in immune system stability. Discover how disruptions in TRPM7 influence immune reactions and pro-inflammatory diseases like multiple sclerosis. Her talk will discuss new insights into TRPM7’s potential as a therapeutic target in controlling inflammatory responses. Prof. Nicolas Demaurex, Geneva Centre for Inflammation Research - UNIGE, Faculté de médecine - UNIGE, University of Geneva 🕒 2:30 - 3:00 pm *Regulation of Innate Immunity by Ion Channels* Join Prof. Demaurex for an exploration into how innate immune cells maintain ionic balance, specifically through calcium channels. His lab's findings on how these channels influence cell function and inflammation control may pave the way for innovative treatments targeting immune cell activity. Discover how STIM, ORAI, and Hv1 proteins impact immune cell performance and combat pathogens. Prof. Yannick Muller, University of Lausanne - UNIL & CHUV | Lausanne university hospital 🕒 3:00 - 3:30 pm *T Regulatory Cell Therapy for Treating Autoimmune Diseases* Prof. Muller will share his research on harnessing regulatory T cells for treating autoimmune diseases. His team is breaking new ground in adoptive cell therapy through genetic engineering and CRISPR technology by modifying T cells to directly target disease-specific antigens. This talk will offer a glimpse into the future of precision immune therapies aimed at restoring immune balance. Connect with experts and peers over coffee after the seminar! Stay with us! ℹ️ All the info is here: https://lnkd.in/dWuYqSAS 🙏 This event is made possible through the generous support of MesenFlow Technologies SARL, Light Chain Bioscience | Novimmune SA, and Amal Therapeutics. #CationChannels #CalciumChannels #InnateImmunity #Immunology #TCells #Physiology #CellSignalling #CellSignaling #Inflammation #CellTherapy #Autoinflammation #MultipleSclerosis #CRISPRCas9 #GeneticEngineering #GCIRSeminar
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🎓 Join us for Margot Piccinno #ThesisDefence! Her research aims to understand the mechanisms by which CD8+ T cells disrupt neuronal metabolic function and how these contribute to neuronal damage in the context of encephalitis. 📅 Monday 4 Nov 🕝 14:30 📍 B02.2526.a CMU Title: Unravelling the neuronal metabolic consequences of CD8+ T cell engagement in a mouse model of encephalitis All the info is here: 🔗 https://lnkd.in/dt6Btb3R Do not miss it out! #Immunology #Neuroimmunology #Encephalitis #Neuron #Brain #Mitochondria #NeuronalMetabolism #MitochondrialDysfunction #SynapticPathology #CentralNervousSystem #WomenInScience #WomenInSTEM #ThesisDefence Director: Professor Doron Merkler, Department of Pathology and Immunology, Faculté de médecine - UNIGE, University of Geneva and HUG - Hopitaux Universitaires de Genève.
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Read the summary of this article! 🔗 https://lnkd.in/dA8R9D2n
Laboratory of Translational Immunology (LTI). Academic research laboratory at the University of Geneva and University Hospitals
We are absolutely thrilled to announce the latest publication from our lab! This is an incredible methodological work that details how to study the interactions of human natural killer cells with porcine endothelial cells in the context of xenotransplantation. A big congratulations to Thao and Viktoriia for going above and beyond to get this paper published. And a huge thank you to all the co-authors and collaborators who made this work possible. https://lnkd.in/e3b3hWxJ
Assessment of NK cytotoxicity and interactions with porcine endothelial cells by live-cell imaging in 2D static and 3D microfluidic systems - Scientific Reports
nature.com
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Transplant Insights 🩺! A study of 16k+ biopsies highlights distinct types of microvascular inflammation in kidney grafts, some linked to higher graft loss risks. These findings could guide better post-transplant care and diagnosis! #Transplantation #Nephrology #KidneyTransplant With the collaboration of Professor Jean Villard, Geneva Centre for Inflammation Research - UNIGE, Faculté de médecine - UNIGE, HUG - Hopitaux Universitaires de Genève. In The New England Journal of Medicine: https://lnkd.in/dKxUDW7E
Microvascular Inflammation of Kidney Allografts and Clinical Outcomes | NEJM
nejm.org
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Congratulations to the team! Proud to have the LTI University of Geneva among the GCIR members! 👏
Laboratory of Translational Immunology (LTI). Academic research laboratory at the University of Geneva and University Hospitals
We are absolutely thrilled to announce the latest publication from our lab! This is an incredible methodological work that details how to study the interactions of human natural killer cells with porcine endothelial cells in the context of xenotransplantation. A big congratulations to Thao and Viktoriia for going above and beyond to get this paper published. And a huge thank you to all the co-authors and collaborators who made this work possible. https://lnkd.in/e3b3hWxJ
Assessment of NK cytotoxicity and interactions with porcine endothelial cells by live-cell imaging in 2D static and 3D microfluidic systems - Scientific Reports
nature.com
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Interested in Immune Cell Signalling? The next GCIR seminar is already planned! 🚀 Join us on Friday 22 November in Geneva to discuss fundamental and clinical aspects of immune cell signalling, from ion level to cell therapy for allergies, autoimmune diseases and transplantation. 📅 22.11 🕑 14h - 15h30 📍 CMU - Müller Programme: 14h00 - 14h30 Prof. Susanna Zierler, Institute of Pharmacology, Johannes Kepler Universität Linz, Austria. "TRPM7 channel-kinase function: from cellular signalling to immune system homeostasis." 14h30 - 15h00 Prof. Nicolas Demaurex, Geneva Centre for Inflammation Research, Department of Cell Physiology and Metabolism, Faculty of Medicine, UNIGE. "Regulation of innate immunity by ion channels" 15h00 - 15h30 Prof. Yannick Muller, Faculty of Biology and Medicine, University of Lausanne - UNIL. "Development of adoptive cell therapy based on regulatory T lymphocytes for autoimmune diseases, allergies and transplantation" 15h30 Coffee for all the attendees Organised by the Geneva Centre for Inflammation Research - UNIGE, Faculté de médecine - UNIGE, University of Geneva with the support of our seminar sponsors, Light Chain Bioscience | Novimmune SA, Amal Therapeutics and MesenFlow Technologies SARL. All the info is here! 🔗 https://lnkd.in/dWuYqSAS #CellSignalling #CellSignaling #Physiology #Immunology #Pharmacology #IonChannels #CellTherapy #Allergy #AutoimmuneDisease #Transplantation #InnateImmunity #CRISPRCas9 #TranslationalResearch
GCIR Seminar 22 Nov 2024 Immune Cell Signalling
unige.ch